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The protein encoded by FTSJ2 is a member of the S-adenosylmethionine-binding protein family. Additionally we are shipping FTSJ2 Proteins (6) and many more products for this protein.
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Targeted exome sequencing of genes encoding the mitochondrial proteome identified a damaging mutation, c.567 G > A, affecting a highly conserved amino acid residue (p.Gly189Arg) of the MRM2 protein. Our findings establish that defective MRM2 causes a MELAS-like phenotype, and suggests the genetic screening of the MRM2 gene in patients with a m.3243 A > G negative MELAS-like presentation.
miR-542-3p functions as a suppressor gene by targeting and upregulating FTSJ2, thus inhibiting the malignancy of non-small cell lung cancer cells
MRM2 and MRM3 are human mitochondrial methyltransferases involved in the modification of 16S rRNA and are important factors for the biogenesis and function of the large subunit of the mitochondrial ribosome.
Data show that 2'-O-methyltransferases MRM1, MRM2, and RNMTL1 are responsible for modification of large subunit rRNA at residues G1145, U1369, and G1370, respectively.
FTSJ2 possesses suppressive effects on the invasion and migration of cancer cells.
FTSJ2 is a nucleolar RNA methyltransferase involved in eukaryotic RNA processing and modification.
RNMTL1, MRM1, and MRM2 (FtsJ2) as members of the RNA methyltransferase family that may be responsible for the three known 2'-O-ribose modifications of the 16 S rRNA core of the large mitochondrial ribosome subunit.
The protein encoded by this gene is a member of the S-adenosylmethionine-binding protein family. It is a nucleolar protein and it may be involved in the processing and modification of rRNA. This gene has been suggested to be involved in cell cycle control and DNA repair.
FtsJ homolog 2
, MRM2 RNA methyltransferase homolog
, cell division protein FtsJ
, protein ftsJ homolog 2
, putative ribosomal RNA methyltransferase 2
, rRNA (uridine-2'-O-)-methyltransferase
, cell division protein ftsJ
, Cell division protein FtsJ
, FtsJ homolog 2 (E. coli)