GPS2 Proteins
GPS2 encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades.
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G Protein Pathway Suppressor 2 (GPS2) (AA 1-327) protein (His tag) Protein
G Protein Pathway Suppressor 2 (GPS2) (AA 1-327) protein (GST tag) Protein
G Protein Pathway Suppressor 2 (GPS2) (AA 228-327) protein (GST tag) Protein
G Protein Pathway Suppressor 2 (GPS2) protein (Myc-DYKDDDDK Tag) Protein
GPS2 Protein Profile
Protein Summary
This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.
Gene names and symbols associated with GPS2
- G protein pathway suppressor 2 (gps2) antibody
- G protein pathway suppressor 2 L homeolog (gps2.L) antibody
- G protein pathway suppressor 2 (GPS2) antibody
- G protein pathway suppressor 2 (Gps2) antibody
- AI505953 antibody
- AMF-1 antibody
- GPS2 antibody
- MGC63588 antibody
- MGC68832 antibody
- MGC133909 antibody
- zgc:63588 antibody
Protein level used designations for GPS2
G protein pathway suppressor 2 , G-protein pathway suppressor 2 , GPS-2
GENE ID | SPECIES |
---|---|
379878 | Xenopus laevis |
393948 | Danio rerio |
403370 | Xenopus laevis |
455229 | Pan troglodytes |
518494 | Bos taurus |
100135707 | Xenopus (Silurana) tropicalis |
100529005 | Ictalurus punctatus |
2874 | Homo sapiens |
56310 | Mus musculus |
497941 | Rattus norvegicus |
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