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GPR22 is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein. Additionally we are shipping GPR22 Proteins (3) and many more products for this protein.
Showing 10 out of 72 products:
Phosphatidylserine mediated hyperactivation of TYRO3 (show TYRO3 Antibodies).TYRO3 (show TYRO3 Antibodies) promotes epithelial cell efferocytosis in a tyrosine kinase (show TXK Antibodies)-dependent manner.TYRO3 role in AKT (show AKT1 Antibodies)-dependent drug resistance.
Taken together, our data indicate that elevated plasma Gas6 (show GAS6 Antibodies) levels is associated with the severity of disease during HTNV infection in humans, suggesting that Gas6 (show GAS6 Antibodies) may play an important role by binding with Tyro3 (show TYRO3 Antibodies) on monocytes.
Study identified the Gas6 (show GAS6 Antibodies)/TAM (show CCNA1 Antibodies) receptor pathway with Tyro3 (show TYRO3 Antibodies) and Mer (show MERTK Antibodies) as novel targets in colorectal cancer.
These results show that TYRO3 (show TYRO3 Antibodies), AXL (show AXL Antibodies) and GAS6 (show GAS6 Antibodies) are expressed at higher levels in LMS and expression of its ligands correlates to a worse PFS in LMS patients.
Patients with macroalbuminuria diabetes had higher circulating levels of sMer and more urinary soluble Tyro3 (show TYRO3 Antibodies) and sMer than normoalbuminuric diabetics. Increased clearance of sTyro3 and sMer was associated with loss of tubular Tyro3 (show TYRO3 Antibodies) and Mer (show MERTK Antibodies) expression in diabetic nephropathy tissue. During in vitro diabetes, human kidney cells had down-regulation of Tyro3 (show TYRO3 Antibodies) and Mer (show MERTK Antibodies) mRNA and increased shedding of sTyro3 and sMer.
TYRO3 (show TYRO3 Antibodies) is overexpressed in the early stage of colon cancer development and aberrant expression of TYRO3 (show TYRO3 Antibodies) promotes tumorigenesis and induces EMT (show ITK Antibodies) through the regulation of SNAI1 (show SNAI1 Antibodies).
In this paper, we review the biology of the Gas6 (show GAS6 Antibodies)/Tyro3 (show TYRO3 Antibodies), Axl (show AXL Antibodies), and MerTK (show MERTK Antibodies)(collectively named TAM (show CCNA1 Antibodies) system)and the current evidence supporting its potential role in the pathogenesis of multiple sclerosis .
these data suggest that Tyro3 (show TYRO3 Antibodies) contributes significantly to tumor growth, aggressiveness and liver dysfunction
Tyro3 (show TYRO3 Antibodies) gene dosage modulates Mertk (show MERTK Antibodies)-associated retinal degeneration, provide strong evidence for a direct role for TYRO3 (show TYRO3 Antibodies) in RPE (show RPE Antibodies) phagocytosis, and suggest that an eQTL (show EQTN Antibodies) can modify a recessive Inherited photoreceptor degenerations.
The mRNA expression levels of Tyro-3 (show TYRO3 Antibodies), Axl (show AXL Antibodies) were decreased in pSS (show CDSN Antibodies) patients. When considering the plasma level, increased levels of soluble Mer (show MERTK Antibodies) was observed with statistically significant difference.
Demonstrate GRR22 expression in mouse heart. Identified a protective role for GPR22 in response to hemodynamic stress resulting from increased afterload.
Gpr22 does not act upstream of the two cilia master regulators, Foxj1a and Rfx2 (show RFX2 Antibodies).
The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.
probable G-protein coupled receptor 22
, tyrosine-protein kinase DTK
, tyrosine-protein kinase RSE
, tyrosine-protein kinase SKY
, tyrosine-protein kinase TIF
, tyrosine-protein kinase byk
, tyrosine-protein kinase receptor TYRO3
, G protein-coupled receptor 22