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GPR37 is a member of the G protein-coupled receptor family. Additionally we are shipping GPR37 Antibodies (81) and GPR37 Proteins (8) and many more products for this protein.
Showing 6 out of 19 products:
REG4 promotes peritoneal metastasis of gastric cancer through GPR37 and triggers a positive feedback loop.
GPR37 was shown to be a component of the CASPR2-MUPP1 complex in brain.
GPR37 may play an important role in the pathogenesis of hepatocellular carcinoma by affecting the proliferation of HCC cells.
Positive role of GPR37 in the proliferation of multiple myeloma cells.
GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin.
results suggested that some alleles in GPR37 were related to the deleterious effect of ASD. GPR37 is associated with the dopamine transporter to modulate dopamine uptake, and regulates behavioral responses to dopaminergic drugs
results show that panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity
Glup/PACRG suppresses cell death induced by accumulation of unfolded Pael receptor and facilitates the formation of Pael-R inclusions.
These results suggest that 4-PBA suppresses ER stress by directly reducing the amount of misfolded protein, including Pael-R accumulated in the ER.
Parkin-ko/Pael-R-tg mice represents an AR-JP mouse model displaying chronic and selective loss of catecholaminergic neurons.
Data show that GPR37 overexpression can induce cellular autophagy, which may prevent the selective degeneration of GPR37-expressing neurons, as reported for Parkinson's and related neurodegenerative diseases.
GPR37 surface trafficking in heterologous cells can be greatly enhanced by N-terminal truncation, coexpression with other receptors, and coexpression with syntenin-1.
This studies revealed that Gpr37(-)(/)(-) mice exhibit dramatically increased loss of myelin in response to cuprizone.
We conclude that GPR37 is crucial for cellular protein quality control during Wnt signaling.
Data suggest that GPR37 regulates central nervous system myelination by controlling the transition from early-differentiated to mature oligodendrocytes.
Knocking-out GPR37 triggers anxiolytic-like effects and regulates hippocampal A2AR-mediated signaling.
These data show functional association between GPR37, prosaposin, and GM1 ganglioside in the plasma membrane.
GPR37 knockout mice show age and sex specific improvements in olfaction, increased anxiety and depression-like behaviors.
Upregulation of Pael-R in the substantia nigra pars compacta of mice by retrograde infection induced endoplasmic reticulum (ER) stress leads to death of dopaminergic neurons.
GPR37 associates with the dopamine transporter to modulate dopamine uptake and behavioral responses to dopaminergic drugs.
Macroautophagy of the GPR37 orphan receptor and Parkinson disease-associated neurodegeneration
This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease.
, Parkin-associated endothelin receptor-like receptor
, endothelin B receptor-like protein 1
, probable G-protein coupled receptor 37
, parkin-associated endothelin B-like receptor
, G protein-coupled receptor 37 (endothelin receptor type B-like)
, G-protein coupled receptor CNS1