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G Protein-Coupled Receptor MRGX2 Proteins (MRGPRX2)

seven transmembrane domain G-protein coupled receptor\; most often found in sensory neurons [RGD, Feb 2006].. Additionally we are shipping G Protein-Coupled Receptor MRGX2 Antibodies (89) and G Protein-Coupled Receptor MRGX2 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MRGPRX2 117194 Q96LB1
MRGPRX2 243978 Q3UG50
Rat MRGPRX2 MRGPRX2 404640  
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Top G Protein-Coupled Receptor MRGX2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$7,626.01
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,355.45
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Wheat germ Human Un-conjugated   2 μg Log in to see 11 to 12 Days
$491.43
Details

MRGPRX2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for G Protein-Coupled Receptor MRGX2 (MRGPRX2) Interaction Partners

Human G Protein-Coupled Receptor MRGX2 (MRGPRX2) interaction partners

  1. Low levels of MRGPRX2 were detected in non-asthma lung mast cells, but its expression was significantly up-regulated in asthma lung mast cells.

  2. the present study demonstrates that FceRI (show FCER1A Proteins) and MRGPRX2 function can be inversely regulated by SCF (show KITLG Proteins) in an acute scenario, suggesting that the signaling requirements differ profoundly between the routes.

  3. The authors discuss the possibility that MRGPRX2 responds to various as-yet-unidentified endogenous ligands that have specific characteristics, and propose that MRGPRX2 plays an important role in regulating inflammatory responses to endogenous harmful stimuli, such as protein breakdown products released from damaged or dying cells.

  4. these peptides are identified as fragments of albumin (show ALB Proteins). The isolated fragments activate MRGPRX2 and degranulate MRGPRX2 expressing LAD (show DLD Proteins) 2 cells in dose-dependent manner. The isolated basic peptides generated from human albumin (show ALB Proteins) are able to degranulate mast cells via the MRGPRX2.

  5. The results showed a kind of mechanism that sinomenine-induced anaphylactoid reactions were mediated by MRGPRX2 via activating PLC (show HSPG2 Proteins) molecular signaling pathways to provoke mast cells Ca(2 (show CA2 Proteins)+) mobilization and degranulation.

  6. data suggest that mast cells play important roles in both gingival homeostasis and periodontal disease by orchestrating an interaction between gingival epithelial cells and neutrophils via MRGPRX2-mediated degranulation

  7. MRGX2 is related to nociception, adrenal gland secretion and mast cell degranulation. (Review)

  8. Ectopic expression of MrgX2 in rat basophilic leukemia RBL-2H3 cells and murine bone marrow mast cells renders these cells responsive to human beta-defensin (show DEFB1 Proteins) for degranulation.

  9. identified MrgX2 as a novel G protein-coupled receptor for the antibacterial peptide LL-37 and demonstrated that unlike most G protein-coupled receptors it is resistant to agonist-induced receptor phosphorylation, desensitization, and internalization.

  10. cortistatin-14 (show CORT Proteins) shown to be a high affinity ligand for G protein coupled receptor MrgX2 which is expressed in dorsal root ganglion

Mouse (Murine) G Protein-Coupled Receptor MRGX2 (MRGPRX2) interaction partners

  1. The results showed a kind of mechanism that sinomenine-induced anaphylactoid reactions were mediated by MRGPRX2 via activating PLC (show HSPG2 Proteins) molecular signaling pathways to provoke mast cells Ca(2 (show CA2 Proteins)+) mobilization and degranulation.

G Protein-Coupled Receptor MRGX2 (MRGPRX2) Protein Profile

Protein Summary

seven transmembrane domain G-protein coupled receptor\; most often found in sensory neurons

Gene names and symbols associated with MRGPRX2

  • MAS related GPR family member X2 (MRGPRX2)
  • MAS-related GPR, member X2 (Mrgprx2)
  • MAS related GPR family member X2 (Mrgprx2)
  • G370024M05Rik protein
  • MrgB1 protein
  • MrgB10 protein
  • Mrgprb1 protein
  • Mrgprb10 protein
  • MRGX2 protein

Protein level used designations for MRGPRX2

G protein-coupled receptor MRGX2 , mas-related G-protein coupled receptor member X2 , MAS-related GPR, member B10 , mas-related G-protein coupled receptor member B10 , MAS-related G protein-coupled receptor, member B1 , MAS-related gene B1

GENE ID SPECIES
117194 Homo sapiens
243978 Mus musculus
404640 Rattus norvegicus
466465 Pan troglodytes
100434444 Pongo abelii
692078 Macaca mulatta
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