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The protein encoded by GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. Additionally we are shipping GTSE1 Kits (4) and GTSE1 Proteins (3) and many more products for this protein.
Showing 10 out of 71 products:
Human Polyclonal GTSE1 Primary Antibody for WB - ABIN526771
Cheeseman, Harry, McAinsh, Prior, Royle: Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension. in Journal of cell science 2013
G2 and S-phase expressed 1 (GTSE1) expression promotes AM progression and correlates with clinical outcomes of patients with acral melanoma (AM), and may represent a promising therapeutic target to suppress AM progression.
GTSE1 is expressed exclusively in late G2 and M phase. From nuclear envelope breakdown until anaphase onset, GTSE1 binds preferentially to the most stable mitotic spindle microtubules and promotes their turnover.
Results indicated for the first time that overexpression of GTSE1 was involved in the progress of HCC (show FAM126A Antibodies), enhancing proliferation and promoting cell invasion in HCC (show FAM126A Antibodies) cells.
GTSE1 inhibition of MCAK (show KIF2C Antibodies) activity regulates the balance of MT stability that determines the fidelity of chromosome alignment, segregation, and chromosomal stability.
Study identifies GTSE1 as a biomarker for cisplatin resistance in gastric cancer cells and suggests its repressive role in cisplatin induced apoptosis making it a potential therapeutic target for better clinical management of gastric cancer patients.
GTSE1 is a microtubule plus-end tracking protein that regulates EB1 (show MAPRE2 Antibodies)-dependent cell migration.
GTSE1 is overexpressed dramatically in lung cancer patients' tissues.
Data show that G2 and S-phase-expressed 1 (GTSE1) protein, a negative regulator of p53 (show TP53 Antibodies), is required for G2 checkpoint recovery and that Plk1 phosphorylation of GTSE1 promotes its nuclear localization.
hGTSE-1 mediated-p21(CIP1/WAF1 (show CDKN1A Antibodies)) stabilization is clearly involved in the ability of cells to counteract cytotoxicity induced by the microtubule poison paclitaxel.
GTSE-1 controls DNA damage-induced apoptosis by affecting p53 (show TP53 Antibodies) function
The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.
G-2 and S-phase expressed 1
, G2 and S phase-expressed protein 1
, G2 and S phase-expressed protein 1-like
, g2 and S phase-expressed protein 1-like
, protein B99 homolog
, G two S phase expressed protein 1