G-Rich RNA Sequence Binding Factor 1 (GRSF1) ELISA Kits

The protein encoded by GRSF1 is a cellular protein that binds RNAs containing the G-rich element. Additionally we are shipping GRSF1 Antibodies (34) and GRSF1 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GRSF1 2926 Q12849
GRSF1 231413 Q8C5Q4
Anti-Rat GRSF1 GRSF1 305256  
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Top GRSF1 ELISA Kits at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human
  96 Tests 15 to 18 Days
$875.60
Details
Mouse
  96 Tests 15 to 18 Days
$875.60
Details

More ELISA Kits for GRSF1 Interaction Partners

Human G-Rich RNA Sequence Binding Factor 1 (GRSF1) interaction partners

  1. our results indicate that GRSF1 helps preserve mitochondrial homeostasis, in turn preventing oxidative DNA damage and the activation of mTOR and NF-kappaB, and suppressing a transcriptional pro-inflammatory program leading to increased IL6 production.

  2. These findings suggest that Twinkle is essential for RNA organization in granules, and that mtSSB is involved in the recently proposed GRSF1-mtRNA degradosome pathway, a route suggested to be particularly aimed at degradation of G-quadruplex prone long non-coding mtRNAs.

  3. These findings indicate that the decline in GRSF1 levels during cellular senescence contributes to impairing mitochondrial function, elevating ROS and DNA damage, suppressing growth, and implementing a pro-inflammatory program.

  4. GRSF1 positively regulates degradosome-dependent decay of non-coding mitochondrial transcripts that form G4 structures. Comprehensive molecular analyses revealed that GRSF1 melts G4 RNA structures in mtRNAs, which facilitates their degradation by the hSuv3-PNPase complex both in vitro and in vivo.

  5. Deletion of either of the three GRSF1 quasi-RNA-recognition motifs (qRRMs) severely impairs RNA-binding.

  6. Data show that some of the naturally occurring guanine-rich RNA sequence binding factor 1 (GRSF1) mutants exhibited a strongly reduced RNA-binding activity although the general protein structure was hardly affected.

  7. HuR and GRSF1 govern the cytoplasmic and mitochondrial localization of the lncRNA RMRP, which is encoded by nuclear DNA but has key functions in mitochondria.

  8. MiR-346 depends on GRSF1 to upregulate another target gene.

  9. Grsf1 controls translation of the protein Use1, possibly by positioning the 40S ribosomal subunit and associated translation factors in front of the translation start site.

  10. The mitochondrial RNA-binding protein GRSF1 localizes to RNA granules and is required for posttranscriptional mitochondrial gene expression.

  11. GRSF1 regulates RNA processing in mitochondrial RNA granules.

  12. GRSF-1 functions by selectively recruiting cellular and viral mRNAs containing 5' UTR GRSF-1 binding sites to polyribosomes, which is mediated through interactions with cellular proteins

Mouse (Murine) G-Rich RNA Sequence Binding Factor 1 (GRSF1) interaction partners

  1. Grsf1 controls translation of the protein Use1, possibly by positioning the 40S ribosomal subunit and associated translation factors in front of the translation start site.

  2. Grsf1 is important for axial elongation, mid/hindbrain development and axial mesoderm specification.

  3. Grsf1 up-regulates translation of GPx4 mRNA and implicate the two proteins in embryonic brain development.

GRSF1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GRSF1

  • G-rich RNA sequence binding factor 1 (GRSF1) antibody
  • G-rich RNA sequence binding factor 1 (grsf1) antibody
  • G-rich RNA sequence binding factor 1 S homeolog (grsf1.S) antibody
  • G-rich RNA sequence binding factor 1 (Grsf1) antibody
  • B130010H02 antibody
  • BB232551 antibody
  • C80280 antibody
  • D5Wsu31e antibody
  • GRSF1 antibody
  • MGC186196 antibody
  • wu:fb62c04 antibody
  • zgc:153305 antibody

Protein level used designations for GRSF1

G-rich RNA sequence binding factor 1 , G-rich sequence factor 1 , G-rich sequence factor 1-like , g-rich sequence factor 1-like , GRSF-1

GENE ID SPECIES
422646 Gallus gallus
471208 Pan troglodytes
475170 Canis lupus familiaris
563249 Danio rerio
706301 Macaca mulatta
100054436 Equus caballus
100158276 Xenopus laevis
100196845 Salmo salar
100228123 Taeniopygia guttata
100337653 Xenopus (Silurana) tropicalis
100396858 Callithrix jacchus
100461219 Pongo abelii
100590863 Nomascus leucogenys
2926 Homo sapiens
527169 Bos taurus
231413 Mus musculus
305256 Rattus norvegicus
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