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The protein encoded by GRSF1 is a cellular protein that binds RNAs containing the G-rich element. Additionally we are shipping GRSF1 Antibodies (32) and GRSF1 Proteins (3) and many more products for this protein.
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Deletion of either of the three GRSF1 quasi-RNA-recognition motifs (qRRMs) severely impairs RNA-binding.
Data show that some of the naturally occurring guanine-rich RNA sequence binding factor 1 (GRSF1) mutants exhibited a strongly reduced RNA-binding activity although the general protein structure was hardly affected.
HuR (show ELAVL1 ELISA Kits) and GRSF1 govern the cytoplasmic and mitochondrial localization of the lncRNA RMRP (show NME1 ELISA Kits), which is encoded by nuclear DNA but has key functions in mitochondria.
MiR (show MLXIP ELISA Kits)-346 depends on GRSF1 to upregulate another target gene.
Grsf1 controls translation of the protein Use1, possibly by positioning the 40S ribosomal subunit and associated translation factors in front of the translation start site.
The mitochondrial RNA-binding protein (show PTBP1 ELISA Kits) GRSF1 localizes to RNA granules and is required for posttranscriptional mitochondrial gene expression.
GRSF1 regulates RNA processing in mitochondrial RNA granules.
GRSF-1 functions by selectively recruiting cellular and viral mRNAs containing 5' UTR (show UTS2R ELISA Kits) GRSF-1 binding sites to polyribosomes, which is mediated through interactions with cellular proteins
Grsf1 is important for axial elongation, mid/hindbrain development and axial mesoderm specification.
Grsf1 up-regulates translation of GPx4 mRNA and implicate the two proteins in embryonic brain development.
The protein encoded by this gene is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro. Multiple transcript variants encoding different isoforms have been found for this gene.
G-rich RNA sequence binding factor 1
, G-rich sequence factor 1
, G-rich sequence factor 1-like
, g-rich sequence factor 1-like