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Involved in translation termination in response to the termination codons UAA, UAG and UGA. Additionally we are shipping GSPT1 Proteins (4) and many more products for this protein.
Showing 10 out of 23 products:
PABP (show PABPC1 Antibodies) enhances the productive binding of the eRF1 (show ZFP36L1 Antibodies)-eRF3 complex to the ribosome, via interactions with the N-terminal domain of eRF3a which itself has an active role in translation termination.
Data found that the N-terminal glycine repeat of eRF3a influences eRF3a-PABP interaction and that eRF3a 12-GGC allele has a decreased binding affinity for PABP.
GAB2 (show GAB2 Antibodies), GSPT1, TFDP2 (show TFDP2 Antibodies) and ZFPM1 (show ZFPM1 Antibodies) are four new susceptibility loci for testicular germ cell tumor.
The survivin and eRF3 complex may function in spindle formation and segregation of chromosomes and cytokinesis.
Overexpression of ID1 (show ID1 Antibodies) in two different cell lines induced STMN3 (show STMN3 Antibodies) and GSPT1 at the transcriptional level, while depletion of ID1 (show ID1 Antibodies) reduced their expression.
The proteolytic cleavage of eRF3a and eRF3b (show GSPT2 Antibodies) into p-eRF3 leads to release an amino-terminal fragment containing nuclear export signal to allow the relocalization of eRF3 into the nucleus to interact with the p14ARF (show CDKN2A Antibodies).
ERF3 is targeted for caspase (show CASP3 Antibodies)-mediated proteolytic cleavage and degradation during DNA damage-induced apoptosis.
Our results show that the presence of the longer allele of eRF3a is correlated with threefold increased risk of breast cancer development
A biological role for the overlapping ERF3 PAM2 motifs in the regulation of deadenylase accessibility to PABPC1 (show PABPC1 Antibodies) at the 3' end of poly(A).
crystal structures of the MLLE domain from PABPC1 in complex with the two PAM2 regions of eRF3
Rac1-GSPT1 represents a novel signaling axis in astrocytes that accelerates proliferation in response to inflammation, which is one important factor in the development of astrogliosis/glial scar following CNS injury
Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
G1 to S phase transition 2
, eukaryotic peptide chain release factor GTP-binding subunit ERF3A
, G1 to S phase transition 1
, eukaryotic peptide chain release factor GTP-binding subunit ERF3A-like
, G1 to S phase transition protein 1 homolog
, eukaryotic peptide chain release factor subunit 3a
, G1 to phase transition 1
, G1-to-S transition GTP binding protein
, eukaryotic polypeptide chain release factor 3
, guanine nucleotide regulatory protein
, G1 to S phase transition protein 1
, G1-to-S phase transition 1