GSPT1 antibody (AA 138-420)

Catalog No. ABIN7267321

This Rabbit Polyclonal antibody specifically detects GSPT1 in WB. It exhibits reactivity toward Human.

Quick Overview for GSPT1 antibody (AA 138-420) (ABIN7267321)

Target: GSPT1 (G1 To S Phase Transition 1 (GSPT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSPT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GSPT1 Antibody

Binding Specificity: AA 138-420

Purpose: GSPT1 Rabbit pAb

Sequence: SMELSEPIEN GETEMSPEES WEHKEEISEA EPGGGSLGDG RPPEESAHEM MEEEEEIPKP KSVVAPPGAP KKEHVNVVFI GHVDAGKSTI GGQIMYLTGM VDKRTLEKYE REAKEKNRET WYLSWALDTN QEERDKGKTV EVGRAYFETE KKHFTILDAP GHKSFVPNMI GGASQADLAV LVISARKGEF ETGFEKGGQT REHAMLAKTA GVKHLIVLIN KMDDPTVNWS NERYEECKEK LVPFLKKVGF NPKKDIHFMP CSGLTGANLK EQSDFCPWYI GLP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 138-420 of human GSPT1 (NP_001123478.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GSPT1

Target: GSPT1 (G1 To S Phase Transition 1 (GSPT1))

Alternative Name: GSPT1

Background: Involved in translation termination in response to the termination codons UAA, UAG and UGA (By similarity. Stimulates the activity of ETF1 (By similarity. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF of mRNA from viruses and cellular genes.,GSPT1,551G9.2,ETF3A,GST1,eRF3a,Epigenetics & Nuclear Signaling,RNA Binding,GSPT1

Molecular Weight: 55kDa/68kDa

Gene ID: 2935

UniProt: P15170