GSPT1 antibody (AA 138-420)

Catalog No. ABIN7267321

Product Details anti-GSPT1 Antibody

Target: GSPT1 (G1 To S Phase Transition 1 (GSPT1))

Binding Specificity: AA 138-420

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSPT1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: GSPT1 Rabbit pAb

Sequence: SMELSEPIEN GETEMSPEES WEHKEEISEA EPGGGSLGDG RPPEESAHEM MEEEEEIPKP KSVVAPPGAP KKEHVNVVFI GHVDAGKSTI GGQIMYLTGM VDKRTLEKYE REAKEKNRET WYLSWALDTN QEERDKGKTV EVGRAYFETE KKHFTILDAP GHKSFVPNMI GGASQADLAV LVISARKGEF ETGFEKGGQT REHAMLAKTA GVKHLIVLIN KMDDPTVNWS NERYEECKEK LVPFLKKVGF NPKKDIHFMP CSGLTGANLK EQSDFCPWYI GLP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 138-420 of human GSPT1 (NP_001123478.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GSPT1

Target: GSPT1 (G1 To S Phase Transition 1 (GSPT1))

Alternative Name: GSPT1 (GSPT1 Products)

Synonyms: eRF3a antibody, etf3a antibody, gspt2 antibody, gst1 antibody, GSPT1 antibody, 551G9.2 antibody, ETF3A antibody, GST1 antibody, AI314175 antibody, AI326449 antibody, AV307676 antibody, C79774 antibody, G1st antibody, Gst-1 antibody, zgc:91975 antibody, G1 to S phase transition 1 L homeolog antibody, G1 to S phase transition 1 antibody, eukaryotic peptide chain release factor GTP-binding subunit ERF3A antibody, gspt1.L antibody, GSPT1 antibody, gspt1 antibody, LOC100413998 antibody, Gspt1 antibody

Background: Involved in translation termination in response to the termination codons UAA, UAG and UGA (By similarity. Stimulates the activity of ETF1 (By similarity. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF of mRNA from viruses and cellular genes.,GSPT1,551G9.2,ETF3A,GST1,eRF3a,Epigenetics & Nuclear Signaling,RNA Binding,GSPT1

Molecular Weight: 55kDa/68kDa

Gene ID: 2935

UniProt: P15170