GATA Binding Protein 6 (GATA6) ELISA Kits

GATA6 is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. Additionally we are shipping GATA6 Antibodies (143) and GATA6 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GATA6 2627 Q92908
GATA6 14465 Q61169
GATA6 29300 P46153
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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
  96 Tests Log in to see 2 to 3 Days
  96 Tests Log in to see 2 to 3 Days
Human < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Log in to see 11 to 18 Days

More ELISA Kits for GATA6 Interaction Partners

Human GATA Binding Protein 6 (GATA6) interaction partners

  1. Genetic variants in GATA6 gene had severe pancreatic atrophy but with abundant beta cells and severe amyloidosis similar to type 2 diabetes.

  2. Study firstly associates GATA6 loss-of-function mutation with increased susceptibility to familial congenital bicuspid aortic valve (BAV) in humans, which provides novel insight into the molecular pathogenesis underlying BAV.

  3. although relatively infrequent in patients with hypertrophic cardiomyopathy, GATA2 (show GATA2 ELISA Kits), 4 and 6 transcription factors may represent a novel insight into the molecular mechanisms related to the pathogenesis of hypertrophic cardiomyopathy

  4. loss of one GATA6 allele affects the differentiation of pancreatic progenitors from the early PDX1 (show PDX1 ELISA Kits)+ stage to the more mature PDX1 (show PDX1 ELISA Kits)+NKX6.1 (show NKX6-1 ELISA Kits)+ stage, leading to impaired formation of glucose-responsive beta-like cells; in addition to this GATA6 haploinsufficiency, also identified dosage-sensitive requirements for GATA6 and GATA4 (show GATA4 ELISA Kits) in the formation of both definitive endoderm and pancreatic progenitor cells

  5. Results show that GATA6 protein levels are reduced in tissue samples from colon cancer patients with miR (show MLXIP ELISA Kits)-196b upregulation and that GATA6 is a direct target of miR (show MLXIP ELISA Kits)-196b.

  6. Our data suggested that miR (show MLXIP ELISA Kits)-124 decreases GATA6 expression by targeting its 3'-UTR (show UTS2R ELISA Kits), which in turn inhibits cholangiocarcinoma invasion and metastasis.

  7. Gain-of-function mutations in GATA6 in both a family with early-onset Atrial Fibrillation and Atrioventricular Septal Defects was found.

  8. analysis of the TNF (show TNF ELISA Kits)-insulin (show INS ELISA Kits) signaling with GATA6 reveals specific patterns of gene expression in cells receiving multiple stimuli

  9. These data show that GATA6 plays a critical role in endoderm and pancreas specification and beta-like cell functionality in humans.

  10. GATA6 variant frequency in sporadic CTDs patients was higher than that in other congenital heart diseases.

Mouse (Murine) GATA Binding Protein 6 (GATA6) interaction partners

  1. Gata6 could be utilized as a biomarker to select the best Pluripotent stem cell (PSC) lines to produce PSC-derived cardiomyocytes.

  2. GATA4 (show GATA4 ELISA Kits)/6 are key regulators of steroidogenesis and testicular somatic cell survival.

  3. Phosphorylation of GATA6 by Erk1/2 (show MAPK1/3 ELISA Kits) compels exit from pluripotent state, and the phosphorylation propels a GATA6 positive feedback regulatory circuit to compel primitive endoderm differentiation

  4. These findings identify Gata6-directed differentiation of neural crest to vascular smooth muscle cells as an essential mechanism that specifies the aortic tree, and provide a new framework for how mutations in GATA6 lead to congenital heart disorders in humans.

  5. Data (including data from studies in knockout mice and transgenic mice) suggest that pancreatic islets in adult mice deficient in GATA6 activity exhibit decreased insulin (show INS ELISA Kits) content and impaired insulin (show INS ELISA Kits) secretion. Gata6-deficient mice are apparently normal at birth; as they age they develop glucose intolerance.

  6. results support a model in which Gata6 contributes to repression of Isl1 (show ISL1 ELISA Kits) expression in the anterior of nascent hindlimb buds.

  7. these findings indicated that the downregulation of GATA-6 effectively inhibited airway inflammation and reversed airway remodeling via Cav-1 (show CAV1 ELISA Kits)

  8. During wound healing differentiated Gata6(+) cells migrate from the sebaceous duct into the interfollicular epidermis and dedifferentiate, acquiring the ability to undergo long-term self-renewal and differentiate into a much wider range of epidermal lineages than in undamaged tissue.

  9. The authors find that Gata6 protects against DNA damage associated with proliferation, thus preventing cell cycle arrest and apoptosis.

  10. Findings indicate that the Gata6 promoter is activated by Esrrb in association with Ncoa3 (show NCOA3 ELISA Kits), and Dax1 inhibited activities of Esrrb and Ncoa3 (show NCOA3 ELISA Kits), resulting maintenance of the undifferentiated status of embryonic stem (ES) cells.

Xenopus laevis GATA Binding Protein 6 (GATA6) interaction partners

  1. Data show that GATA4 or 6 regulate both cardiogenic potential and subsequent cardiomyocyte differentiation but that GATA5 is involved in regulating cardiomyocyte differentiation.

  2. Results describe the expression of GATA4 (show GATA4 ELISA Kits) and 6 during gastrulation and their function in migratory behaviour.

  3. several transcription factors, that is SRF, myocardin, and GATA6, that induce the expression of SM-MHC in animal cap cells

Zebrafish GATA Binding Protein 6 (GATA6) interaction partners

  1. these data suggest an essential role for Pak1 (show PAK1 ELISA Kits) as an Erk (show MAPK1 ELISA Kits) activator, and Gata6 as an Erk (show MAPK1 ELISA Kits) target, during neural crest development.

  2. specification of cardiac fate downstream of gata5/6 involves activation of the tmem88a gene to constrain WNT (show WNT2 ELISA Kits) signaling and expand the number of cardiac progenitors.

  3. in zebrafish the gata6 genes are redundant for specification of cardiomyocytes.

  4. Results suggest that GATA4 and -6 play a key role in the regulation of ventricular myosin heavy chain gene expression in the ventricle.

Pig (Porcine) GATA Binding Protein 6 (GATA6) interaction partners

  1. investigation of genes regulated by GATA6, GATA4 (show GATA4 ELISA Kits), and both in combination: studies in granulosa cells primed for luteinization

  2. The altered ratio of GATA4 (show GATA4 ELISA Kits) to GATA6 after ovulation may allow GATA6 to enhance STAR mRNA accumulation.

Cow (Bovine) GATA Binding Protein 6 (GATA6) interaction partners

  1. GATA4 (show GATA4 ELISA Kits) and GATA6 mRNA and proteins could be detected in bovine corpus luteum (CL). GATA6 showed a marked decrease at the regressed luteal stage, like NR5A1 (show NR5A1 ELISA Kits), NR5A2 (show NR5A2 ELISA Kits), and the other steroidogenic markers.

GATA6 Antigen Profile

Antigen Summary

This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects.

Gene names and symbols associated with GATA6

  • GATA binding protein 6 (GATA6) antibody
  • GATA binding protein 6 (Gata6) antibody
  • GATA binding protein 6 (gata6) antibody
  • GATA binding protein 6 L homeolog (gata6.L) antibody
  • AA410133 antibody
  • cb603 antibody
  • GATA-5 antibody
  • gata-6 antibody
  • gata6 antibody
  • gata6a antibody
  • gata6b antibody
  • pnr antibody
  • tGata6 antibody
  • XGATA-6 antibody
  • XGATA6 antibody

Protein level used designations for GATA6

GATA-binding factor 6 , transcription factor GATA-6 , GATA-binding protein 6 , DNA-binding protein GATA-GT2 , zinc-finger transcription factor Gata6 , GATA-6 transcription factor , GATA-binding factor 6-B , transcription factor xGATA-6B , GATA binding protein 6 , transcription factor GATA-6-like , GATA-6 , LOW QUALITY PROTEIN: transcription factor GATA-6 , transcription factor GATA6

2627 Homo sapiens
14465 Mus musculus
29300 Rattus norvegicus
395062 Xenopus (Silurana) tropicalis
396390 Gallus gallus
399082 Xenopus laevis
490520 Canis lupus familiaris
100228783 Taeniopygia guttata
100434852 Pongo abelii
58076 Danio rerio
397600 Sus scrofa
654400 Bos taurus
100720264 Cavia porcellus
468495 Pan troglodytes
100820751 Ovis aries musimon
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