GRB2-Related Adaptor Protein (GRAP) ELISA Kits

The protein encoded by GRAP, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. Additionally we are shipping GRAP Antibodies (66) and GRAP Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GRAP 10750 Q13588
GRAP 71520 Q9CX99
Anti-Rat GRAP GRAP 363616  
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Top GRAP ELISA Kits at antibodies-online.com

Showing 3 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details
Human < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details
Cow
  96 Tests Log in to see 15 to 18 Days
$1,029.60
Details

More ELISA Kits for GRAP Interaction Partners

Human GRB2-Related Adaptor Protein (GRAP) interaction partners

  1. The function of the growth factor receptor-bound protein 2 (GRB2)-related adaptor protein (GRAP) in the auditory system is not known.

  2. Findings suggest that the miR-654-5p/GRAP/Ras/Erk signaling pathway in OSCC cells might contribute to the underlying mechanism through which miR-654-5p participates in the regulation of OSCC progression.

  3. Grb2-related adaptor protein (GRAP) was up-regulated in kidney tubules from fibrotic kidneys from diabetic patients, and subsequently confirmed as a novel component of TGF-beta signaling in cultured human renal tubule cells.

  4. Results suggest that the GRAP gene might have a role in the pathogenesis of Sjogren's syndrome.

  5. Our findings define a pathway involving CD28 binding to Grb-2 and its co-operativity with Vav1 in the regulation of T-cell co-stimulation.

Mouse (Murine) GRB2-Related Adaptor Protein (GRAP) interaction partners

  1. Grb2-related adaptor protein (GRAP) was up-regulated in kidney tubules from diabetic mice, indicating a potential novel role for GRAP in TGF-beta-induced tubule injury in diabetic kidney disease.

  2. Data suggest that Grap, unlike Grb2, acts as a negative regulator of TCR-stimulated intracellular signaling by downregulating signal relay through the Ras/Erk pathway.

  3. Results suggest that the GRAP gene might have a role in the pathogenesis of Sjogren's syndrome.

  4. FcgammaRIIB docking site for the SH2 domain-containing adapters Grb2 and Grap

GRAP Antigen Profile

Antigen Summary

This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

Gene names and symbols associated with GRAP

  • GRB2-related adaptor protein (GRAP) antibody
  • GRB2-related adaptor protein (Grap) antibody
  • GRB2-related adapter protein (LOC489534) antibody
  • GRB2-related adaptor protein a (grapa) antibody
  • GRB2-related adaptor protein b (grapb) antibody
  • GRB2-related adapter protein (LOC100727005) antibody
  • 8430435N19Rik antibody
  • BB233594 antibody
  • Grap antibody
  • MGC109892 antibody
  • si:dkeyp-9d4.1 antibody
  • zgc:110202 antibody

Protein level used designations for GRAP

GRB2-related adapter protein , growth factor receptor-bound protein 2-related adaptor protein , GRB2-related adaptor protein

GENE ID SPECIES
10750 Homo sapiens
71520 Mus musculus
363616 Rattus norvegicus
416523 Gallus gallus
489534 Canis lupus familiaris
534491 Bos taurus
553596 Danio rerio
555184 Danio rerio
100727005 Cavia porcellus
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