GRB2-Related Adaptor Protein (GRAP) ELISA Kits

GRAP encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. Additionally we are shipping GRAP Antibodies (59) and GRAP Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GRAP 10750 Q13588
GRAP 71520 Q9CX99
Anti-Rat GRAP GRAP 363616  
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Top GRAP ELISA Kits at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human
  96 Tests Log in to see 15 to 18 Days
$875.60
Details
Mouse
  96 Tests Log in to see 15 to 18 Days
$875.60
Details
Cow
  96 Tests Log in to see 15 to 18 Days
$1,029.60
Details

More ELISA Kits for GRAP Interaction Partners

Human GRB2-Related Adaptor Protein (GRAP) interaction partners

  1. A compound mutation consisting of a large deletion and a nonsense mutation, which provides a new insight in the mutation type of CTSC (show CTSC ELISA Kits) gene.

  2. CTSC (show CTSC ELISA Kits) gene missense mutation is responsible for Papillo- Lefevre syndrome in a Turkish family.

  3. analysis of fluorescent substrates provides a detailed S' specificity study of cathepsin C (show CTSC ELISA Kits)

  4. Mutation screening of the CTSC (show CTSC ELISA Kits) gene from the two patients revealed the presence of the same homozygous nonsense mutation in Papillon-Lefevre syndrome and Haim-Munk syndromes. Phenotypic variants of the same rare disease caused by mutations of the cathepsin C (CTSC (show CTSC ELISA Kits)) gene.

  5. Neutrophilic Cathepsin C (show CTSC ELISA Kits) Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.

  6. CTSC (show CTSC ELISA Kits) was associated with albuminuria in type 2 diabetes patients.

  7. Homozygous mutation 901G>A in exon 7 of CTSC (show CTSC ELISA Kits) gene is associated with Papillon-Lefevre syndrome.

  8. Results identify a missense mutation in CTSC (show CTSC ELISA Kits) gene that segregate within a family with Papillon-Lefevre syndrome.

  9. Papillon-Lefevre syndrome cause by homozygous nonsense mutation of cathepsin C (show CTSC ELISA Kits) gene.

  10. CatC (show CTSC ELISA Kits) has a role in the selective tuning of innate and adaptive immune responses, relevant to a chronic immune disease, such as atherosclerosis.

Mouse (Murine) GRB2-Related Adaptor Protein (GRAP) interaction partners

  1. Grb2-related adaptor protein (GRAP) was up-regulated in kidney tubules from diabetic mice, indicating a potential novel role for GRAP in TGF-beta (show TGFB1 ELISA Kits)-induced tubule injury in diabetic kidney disease.

  2. Data suggest that Grap, unlike Grb2 (show GRB2 ELISA Kits), acts as a negative regulator of TCR-stimulated intracellular signaling by downregulating signal relay through the Ras/Erk (show EPHB2 ELISA Kits) pathway.

  3. Results suggest that the GRAP gene might have a role in the pathogenesis of Sjogren's syndrome.

  4. FcgammaRIIB docking site for the SH2 domain-containing adapters Grb2 (show GRB2 ELISA Kits) and Grap

GRAP Antigen Profile

Antigen Summary

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GRAP

  • GRB2-related adaptor protein (GRAP) antibody
  • cathepsin C (CTSC) antibody
  • GRB2-related adaptor protein (Grap) antibody
  • GRB2-related adapter protein (LOC489534) antibody
  • GRB2-related adaptor protein a (grapa) antibody
  • GRB2-related adaptor protein b (grapb) antibody
  • GRB2-related adapter protein (LOC100727005) antibody
  • 8430435N19Rik antibody
  • BB233594 antibody
  • CPPI antibody
  • DPP-I antibody
  • DPP1 antibody
  • DPPI antibody
  • Grap antibody
  • HMS antibody
  • JP antibody
  • JPD antibody
  • MGC109892 antibody
  • PALS antibody
  • PDON1 antibody
  • PLS antibody
  • si:dkeyp-9d4.1 antibody
  • zgc:110202 antibody

Protein level used designations for GRAP

GRB2-related adapter protein , growth factor receptor-bound protein 2-related adaptor protein , cathepsin J , dipeptidyl peptidase 1 , dipeptidyl peptidase I , dipeptidyl transferase , dipeptidyl-peptidase I , GRB2-related adaptor protein

GENE ID SPECIES
10750 Homo sapiens
1075 Homo sapiens
71520 Mus musculus
363616 Rattus norvegicus
416523 Gallus gallus
489534 Canis lupus familiaris
534491 Bos taurus
553596 Danio rerio
555184 Danio rerio
100727005 Cavia porcellus
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