anti-GTP Binding Protein 3 (Mitochondrial) (GTPBP3) Antibodies

This locus encodes a GTP-binding protein. Additionally we are shipping GTPBP3 Kits (6) and GTPBP3 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GTPBP3 290633 Q5PQQ1
GTPBP3 70359 Q923K4
GTPBP3 84705 Q969Y2
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Top anti-GTPBP3 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: GTPBP3 Antibody [NBP1-91974] - Staining of human colon shows strong cytoplasmic positivity in glandular cells. Western Blot: GTPBP3 Antibody [NBP1-91974] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated WB GTPBP3 Antibody (Center) (ABIN1881398) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the GTPBP3 antibody detected the GTPBP3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB Western blot analysis in NCI-H460 cell line lysates (35ug/lane). 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of NCI-H460 cells, using GTPBP3 antibody (ABIN5972928). 100 μL Log in to see 11 to 16 Days
$412.19
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: GTPBP3 Antibody [NBP2-16765] - A: IMR32 Immunohistochemistry-Paraffin: GTPBP3 Antibody [NBP2-16765] - Human brain. 0.1 mL Log in to see 8 to 11 Days
$516.98
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 11 to 12 Days
$305.71
Details
Human Mouse Un-conjugated WB Western Blot analysis of GTPBP3 expression in transfected 293T cell line by GTPBP3 MaxPab polyclonal antibody.Lane 1: GTPBP3 transfected lysate(54.12 KDa).Lane 2: Non-transfected lysate. GTPBP3 MaxPab polyclonal antibody. Western Blot analysis of GTPBP3 expression in Jurkat. 50 μg Log in to see 11 to 12 Days
$440.00
Details
Mouse Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$658.43
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 11 to 14 Days
$1,101.83
Details

Top referenced anti-GTPBP3 Antibodies

  1. Human Polyclonal GTPBP3 Primary Antibody for WB - ABIN1881398 : Villarroya, Prado, Esteve, Soriano, Aguado, Pérez-Martínez, Martínez-Ferrandis, Yim, Victor, Cebolla, Montaner, Knecht, Armengod: Characterization of human GTPBP3, a GTP-binding protein involved in mitochondrial tRNA modification. in Molecular and cellular biology 2008 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal GTPBP3 Primary Antibody for IHC - ABIN966243 : Li, Guan: A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation. in Molecular and cellular biology 2002 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal GTPBP3 Primary Antibody for ICC, IF - ABIN4316447 : Kopajtich, Nicholls, Rorbach, Metodiev, Freisinger, Mandel, Vanlander, Ghezzi, Carrozzo, Taylor, Marquard, Murayama, Wieland, Schwarzmayr, Mayr, Pearce, Powell, Saada, Ohtake, Invernizzi, Lamantea et al.: Mutations in GTPBP3 cause a mitochondrial translation defect associated with hypertrophic cardiomyopathy, lactic acidosis, and encephalopathy. ... in American journal of human genetics 2014 (PubMed)

More Antibodies against GTPBP3 Interaction Partners

Zebrafish GTP Binding Protein 3 (Mitochondrial) (GTPBP3) interaction partners

  1. defective expression of gtpbp3 related to tRNA modification alters the mitochondrial function and development of zebrafish

Mouse (Murine) GTP Binding Protein 3 (Mitochondrial) (GTPBP3) interaction partners

  1. These observations suggest that the mouse Gtpbp3 is an evolutionarily conserved mitochondrial GTP-binding protein involved in the tRNA modification.

Human GTP Binding Protein 3 (Mitochondrial) (GTPBP3) interaction partners

  1. Low GTPBP3 expression is associated with Mitochondrial diseases in neoplasms.

  2. Defects in the mitochondrial tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARgamma-UCP2-AMPK axis.

  3. GTPBP3 defective expression is associated with an mitochondrial-tRNA hypomodification status.GTPBP3 plays a role in the regulation of UCP2 and MCP1 proteins through AMPK signaling.

  4. Results show that post-transcriptional expression of GTPBP3, MTO1 and TRMU genes is down-regulated, leading to mt-tRNA hypomodification and contributing to mitochondrial dysfunction in MELAS cybrids.

  5. Most individuals with GTPBP3 mutations developed neurological symptoms and MRI involvement of thalamus, putamen, and brainstem resembling Leigh syndrome.

  6. GTPBP3 localizes in the mitochondria and is a deafness-associated homolog of yeast MSS1.

  7. Phenotype of non-syndromic deafness associated with the mitochondrial A1555G mutation is modulated by mitochondrial RNA modifying enzymes MTO1 and GTPBP3.

  8. Data show that the two most abundant GTPBP3 isoforms exhibit moderate affinity for guanine nucleotides like their bacterial homologue, MnmE, although they hydrolyze GTP at a 100-fold lower rate.

GTPBP3 Antigen Profile

Protein Summary

This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with GTPBP3

  • GTP binding protein 3, mitochondrial (GTPBP3) antibody
  • GTP binding protein 3 (Gtpbp3) antibody
  • GTP binding protein 3, mitochondrial (gtpbp3) antibody
  • 2410009F13Rik antibody
  • AI607903 antibody
  • GTPBG3 antibody
  • GTPBP3 antibody
  • MSS1 antibody
  • MTGP1 antibody
  • THDF1 antibody
  • zgc:112394 antibody

Protein level used designations for GTPBP3

GTP binding protein 3 (mitochondrial) , tRNA modification GTPase GTPBP3, mitochondrial , tRNA modification GTPase GTPBP3, mitochondrial-like , GTP-binding protein 3 , mitochondrial GTP-binding protein 1

GENE ID SPECIES
484838 Canis lupus familiaris
539656 Bos taurus
100070158 Equus caballus
100392904 Callithrix jacchus
100474937 Ailuropoda melanoleuca
290633 Rattus norvegicus
553807 Danio rerio
70359 Mus musculus
84705 Homo sapiens
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