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Induces apoptosis.. Additionally we are shipping Gasdermin A Antibodies (31) and many more products for this protein.
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modest changes (8-13%) in promoter methylation levels of ZPBP2 (show ZPBP2 Proteins) and GSDMA may cause substantial changes in RNA levels and allelic expression of ZPBP2 (show ZPBP2 Proteins) and ORMDL3 (show ORMDL3 Proteins) is mediated by DNA methylation (show HELLS Proteins)
GSDMA was identified as a susceptibility gene for systemic sclerosis.
we investigated the association between GSDMA and GSDMB (show GSDMB Proteins) variants and the incidence of adult and childhood asthma among Jordanians.An association between the GSDMB (show GSDMB Proteins) T/C single nucleotide polymorphism (SNP) genotype and the incidence of childhood asthma was found
The local genotype influences methylation levels at SLC22A5 (show SLC22A5 Proteins) and ZPBP2 (show ZPBP2 Proteins) promoters independently of the asthma status. Further studies are necessary to confirm the relationship between GSDMA-ZPBP2 (show ZPBP2 Proteins) and SLC22A5 (show SLC22A5 Proteins) methylation and asthma in females and males separately.
Based on our results and published findings on GSDMA, GSDMB, LRRC3C, and related proteins, we propose that this locus in part affects IBD susceptibility via effects on apoptosis and cell proliferation
Study identified significantly white blood cell count (WBC) level associated SNPs of three separate genes GSDMA, MED24 (show MED22 Proteins), and PSMD3 (show PSMD3 Proteins) in European continent (EA) subjects.
The GSDMA (rs7212938) and GSDMB (show GSDMB Proteins) (rs7216389) polymorphisms are associated with asthma susceptibility and intermediate asthma phenotypes.
Results suggest an association of 17q21 polymorphisms with ORMDL3 (show ORMDL3 Proteins), GSDMA expression, and IL-17 (show IL17A Proteins) secretion early in life. These observations may imply a functional role of the 17q21 locus affecting T-cell development during immune maturation.
The present data suggest that TGF-beta (show TGFB1 Proteins), LMO1 (show LMO1 Proteins), possibly RUNX3 (show RUNX3 Proteins), and GSDM form a regulatory pathway for directing the pit (show IRF6 Proteins) cells to apoptosis.
Study investigated the expression pattern of the GSDM family genes in the upper gastrointestinal epithelium and cancers.
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