anti-Gastrin (GAST) Antibodies

C16ORF53 (PA1) is a component of a Set1-like multiprotein histone methyltransferase complex (Cho et al., 2007 [PubMed 17500065]).[supplied by OMIM, May 2008].. Additionally we are shipping Gastrin Kits (116) and Gastrin Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GAST 2520 P01350
GAST 14459 P48757
GAST 25320 P04563
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Top anti-Gastrin Antibodies at

Showing 10 out of 155 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Gastrin staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Gastrin staining in human stomach formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL 13 to 14 Days
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using Gastrin Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using Gastrin Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
Human Guinea Pig Un-conjugated IHC (fro), IF, IHC (p)   50 μL 6 to 8 Days
Human Rabbit Un-conjugated ELISA, IF, IHC, IHC (p), WB 100 μL 11 to 14 Days
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB ABIN6266887 staining NIH/3T3 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. Western blot analysis on NIH-3T3 cell lysate using Gastrin Antibody,The lane on the left is treated with the antigen-specific peptide. 100 μL 11 to 12 Days
Human Rabbit Un-conjugated EIA, WB   0.1 mg 4 to 8 Days
Human Mouse Un-conjugated WB 0.1 mL 11 to 14 Days
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg 6 to 8 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human gastric parietal cells labeled with Anti-Gastrin Polyclonal Antibody, Unconjugated (ABIN673119) followed by conjugation to the secondary antibody and DAB staining Paraformaldehyde-fixed, paraffin embedded mouse stomach tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-Gastrin Polyclonal Antibody, Unconjugated  at 1:200 overnight at 4°C, followed by a conjugated secondary and DAB staining 100 μL 3 to 7 Days
Human Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Rat Stomach lysate; Primary Ab: 5µg/ml Rabbit Anti-Human GT Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg 15 to 18 Days

Top referenced anti-Gastrin Antibodies

  1. Human Polyclonal Gastrin Primary Antibody for IHC (fro), IF - ABIN113496 : Portela-Gomes, Stridsberg, Johansson, Grimelius: Complex co-localization of chromogranins and neurohormones in the human gastrointestinal tract. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1997 (PubMed)
    Show all 7 Pubmed References

More Antibodies against Gastrin Interaction Partners

Human Gastrin (GAST) interaction partners

  1. feedback between the level of ghrelin and gastrin in the blood of patients with chronic gastritis and type 2 diabetes mellitus; with increasing levels of gastrin in the blood, the level of ghrelin in the blood decreases and vice versa

  2. The same markers were also expressed in a proportion of adenocarcinomas supporting the view that gastrin is important in the development of gastric cancer

  3. We concluded that low serum gastrin is related to increased risk of ER(+) BC development. The results also established that CCKBR/ERK/P65 signaling function is generally tumor suppressive in ER(+) BC, indicating therapies should focus on restoring, not inhibiting, CCKBR/ERK/P65 pathway activity.

  4. Study reveals that Galphas binds to RGS1 and plays a necessary role during RGS1mediated promotion of melanoma proliferation and migration.

  5. Gastrin and BCL2 apoptosis regulator (Bcl2) are highly expressed in gastric cancer tissues, and they are correlated with the clinicopathologic features.

  6. Everolimus down-regulates the systemic levels of gastrin and glucagon in patients with pancreatic neuroendocrine tumors.

  7. we suggest that gastrin contributes to the emergence of MDR of SGC7901 cells via the degradation of p27Kip1

  8. Results demonstrate that gastrin increases the expression of the autophagy markers MAP1LC3B-II and SQSTM1 in gastric adenocarcinoma cells. Gastrin induces autophagy via activation of the STK11-PRKAA2-ULK1 and that this signaling pathway is involved in increased migration and cell survival.

  9. PTHLH is a gastrin-regulated growth factor that might contribute to gastric epithelial cell homeostasis.

  10. Gastrin is expressed in both insulin(+) and somatostatin(+) cells in adults with type 2 diabetes.

  11. Gastrin induced ABCG2 expression by activating NF-kappaB and thereby modulated the side population proportion, tumor cell metastatic potential and invasion activity in pancreatic cancer.

  12. CTGF is overexpressed in gastric cancer and adjacent tissue compared to normal gastric tissue. Gastrin induces expression of CTGF in gastric epithelial cells.

  13. Data show that 6 of 20 primary pancreatic neuroendocrine tumors (PNETs) had positive staining for multiple hormones gastrin, insulin, glucagon, and somatostatin, and positive expression of 1 or more hormones was found in 9 of 12 nonfunctioning PNETs [NF-PNETs]) patients.

  14. Gastrin role in gastric epithelial homeostasis and gastric carcinogenesis

  15. Results suggest a role for Toll-like receptor 4 in gastric acid regulation and that the Toll-like receptor 4 (TLR4) +896 and +1196 wild type homozygozity increases peptic ulcer risk via gastrin secretion.

  16. Serum pepsinogens I (PGI) and II (PGII), gastrin 17 (G-17), and antibodies against whole H. pylori, or cytotoxin-associated gene A (CagA) antigen among 309 consecutive patients, were measured.[Pepsinogen I, Gastrin 17]

  17. treatment with gastrin, a CCK2R agonist, stimulated the secretion of GLP-1, and that this effect was likely due to increased expression of proglucagon and PCSK1 (also known as prohormone convertase 3 (PC3 gene)).

  18. Gastrin stimulates MMP-1 expression in gastric epithelial cells and stimulates cell migration.

  19. Progastrin is a new pro-angiogenic factor in colorectal cancer and an attractive therapeutic target.

  20. Small (

Mouse (Murine) Gastrin (GAST) interaction partners

  1. Gastrin induces nuclear export and proteasome degradation of menin in duodenal glial cells.

  2. PTHLH is a gastrin-regulated growth factor that might contribute to gastric epithelial cell homeostasis.

  3. Renal-selective silencing of Gast by the renal subcapsular injection of Gast siRNA in BALB/c mice decreases renal dopamine production and increases blood pressure.

  4. Gastrin is expressed in insulin secreting cells of adult diabetic mice.

  5. CTGF is overexpressed in gastric cancer and adjacent tissue compared to normal gastric tissue. Gastrin induces expression of CTGF in gastric epithelial cells.

  6. increased circulating concentrations of progastrin provide a physiological advantage against systemic hypoxia in mice

  7. Ihh signaling mediates gastrin-induced proliferation of epithelial cells in stomachs of adult mice.

  8. mouse corneal afferent sensory neurons expressed CCK and GAST, and the CCK1R receptors.

  9. Data indicate that epithelial Gli2 expression was sufficient to stimulate Il-1beta expression, repress Gast gene expression and increase proliferation, leading to antral hyperplasia.

  10. gastrins play an important direct role, unrelated to their ability to stimulate acid secretion, in hematopoiesis under conditions of iron deficiency.

  11. Initiation of antral gastric cancer is associated with progressive epigenetic silencing of TFF1, which can be suppressed by the hormone gastrin.

  12. Regulation of mouse gastrin gene in vivo. Mechanisms involved in transcriptional control of the gastrin gene.

  13. RegI and gastrin may synergistically regulate gastric mucosal proliferation during certain pathological settings like wound healing

  14. To examine the importance of gastrin or its receptors during development in general and for gastric physiology specifically both have been knocked out.

  15. stimulates the growth of gastric pit cell precursors by inducing its own receptors.

  16. Endocrine gastrin may have a role in the colonic adenoma carcinoma sequence. Hyper-gastrinaemia may promote proliferation of human colonic adenomas that express CCK-2 receptor isoforms.

  17. Parietal cells were found to be significantly smaller in the mutant cell preparations, suggesting that gastrin stimulation modulates parietal cell morphology.

  18. essential physiologic role for gastrin in glucose homeostasis; however, the gastrin gene is not essential for murine islet development or the adaptive islet proliferative response to beta-cell injury.

  19. Lack of gastrin impairs gastrin-enterochromaffin-like cell axis, whereas lack of gastrin and CCK impairs both hormonal pathways. In gastrin-CCK double-knockout mice, acid secretion is controlled by cholinergic vagal stimulation, normalizing acid output.

  20. Cis-acting element mediating gastrin responsiveness was mapped to the -69 to -58 region of the HB-EGF promoter. Gastrin stimulation was PKC dependent and at least partially mediated by activation of the EGF receptor.

Guinea Pig Gastrin (GAST) interaction partners

  1. Serum gastrin decreased significantly in the cholesterol gallstone groups compared to the control group.

Gastrin (GAST) Antigen Profile

Protein Summary

Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17.

Gene names and symbols associated with anti-Gastrin (GAST) Antibodies

  • gastrin (GAST) antibody
  • gastrin (Gast) antibody
  • Gas antibody
  • GAST antibody
  • PPG34 antibody

Protein level used designations for anti-Gastrin (GAST) Antibodies

preprogastrin , gastrin

2520 Homo sapiens
14459 Mus musculus
25320 Rattus norvegicus
280800 Bos taurus
445524 Sus scrofa
468262 Pan troglodytes
707564 Macaca mulatta
100034214 Equus caballus
100714563 Cavia porcellus
100685087 Canis lupus familiaris
101092065 Felis catus
101119230 Ovis aries
102179807 Capra hircus
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