anti-General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1) Antibodies

may act as a muscle specific transcription factor\; human homolog may be associated with the Williams-Beuren microdeletion syndrome [RGD, Feb 2006]..

list all antibodies Gene Name GeneID UniProt
Anti-Rat GTF2IRD1 GTF2IRD1 246770  
Anti-Mouse GTF2IRD1 GTF2IRD1 57080 Q9JI57
Anti-Human GTF2IRD1 GTF2IRD1 9569 Q9UHL9
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Top anti-GTF2IRD1 Antibodies at antibodies-online.com

Showing 10 out of 98 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Human kidney WB Suggested Anti-GTF2IRD1 Antibody Titration:  2.5ug/ml  ELISA Titer:  1:312500  Positive Control:  Transfected 293T 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated IHC, WB Human kidney WB Suggested Anti-GTF2IRD1 Antibody Titration:  2.5ug/ml  ELISA Titer:  1:312500  Positive Control:  Transfected 293T 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated IHC, WB Human kidney WB Suggested Anti-GTF2IRD1 Antibody Titration:  2.5ug/ml  Positive Control:  Transfected 293T 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IP, IHC, WB Immunohistochemical analysis of GTF2IRD1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated Western blot analysis of GTF2IRD1 expression in Hela (A), HEK293T (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from 293 cells, using GTF2IRD1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$242.88
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 16 Days
$181.73
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IP, IHC, WB Western Blot and Immunoprecipitation: GTF2IRD1/TFII-IRD1 Antibody [ABIN253195] - Detection of Human GTF2IRD1/TFII-IRD1 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-GTF2IRD1/TFIIIRD1 antibody ABIN253195 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. GTF2IRD1/TFII-IRD1 was also immunoprecipitated by rabbit anti-GTF2IRD1/TFII-IRD1 antibody ABIN253194, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes Immunohistochemistry-Paraffin: GTF2IRD1 Antibody [ABIN2531956] - Human prostate carcinoma. Antibody used at a dilution of 1:200. 0.1 mL Log in to see 7 to 9 Days
$556.31
Details
Human Rabbit Un-conjugated WB GTF2IRD1 Antibody (N-term)  western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the GTF2IRD1 antibody detected the GTF2IRD1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP Western Blot and Immunoprecipitation: GTF2IRD1/TFII-IRD1 Antibody [ABIN253194] - Detection of Human GTF2IRD1/TFII-IRD1 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-GTF2IRD1/TFII-IRD1 antibody ABIN253194 used for IP at 3 mcg/mg lysate. GTF2IRD1/TFII-IRD1 was also immunoprecipitated by rabbit anti-GTF2IRD1/TFII-IRD1 antibody NB100-60156, which recognizes a downstream epitope. Immunohistochemistry-Paraffin: GTF2IRD1 Antibody [ABIN2531945] - Human prostate carcinoma. Antibody used at a dilution of 1:5,000. 100 μL Log in to see 7 to 9 Days
$556.31
Details

More Antibodies against GTF2IRD1 Interaction Partners

Cow (Bovine) General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1) interaction partners

  1. cGMP-dependent protein kinase (show CDK7 Antibodies) Ibeta binds to TFII-I (show GTF2I Antibodies) and IRAG (show MRVI1 Antibodies) through a common interaction motif

Mouse (Murine) General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1) interaction partners

  1. The mis-regulation of genes downstream of GTF2IRD1, including TbetaR2 and BMPR1b, also individually promoted mammary cancer development, and silencing of TbetaR2 suppressed GTF2IRD1-driven tumor promotion.

  2. the absence of GTF2IRD1 is associated with increased expression of genes involved in cellular proliferation, including growth factors consistent with the observed phenotype of extreme thickening of the epidermis.

  3. Gtf2ird1 is essential for Mkx (show MKX Antibodies) transcription, while also linking mechanical forces to Mkx (show MKX Antibodies)-mediated tendon homeostasis and regeneration.

  4. Gtf2ird1 is expressed in a number of cell types within the cochlea. Gtf2ird1 null mice showed higher auditory thresholds.

  5. findings suggest an important role for GTF2IRD1 in regulating the level and topology of rod and cone gene expression, and in maintaining normal retinal function.

  6. GTF2IRD2 (show GTF2IRD2 Antibodies) has evolved as a regulator of GTF2IRD1 and TFII-I (show GTF2I Antibodies); inhibiting their function by direct interaction and sequestration into inactive nuclear zones.

  7. This study presented that role for GTF2IRD1 in the motoric and anxiety-related abnormalities seen in Williams-Beuren syndrome, and suggests basal ganglia and potentially cerebellar abnormalities in Gtf2ird1 mice.

  8. Widespread and robust expression of Gtf2ird1 protein in the developing rodent brain, is reported.

  9. Data show the existence of a negative autoregulatory mechanism that controls the level of GTF2IRD1 transcription via direct binding of the GTF2IRD1 protein to a highly conserved region of the GTF2IRD1 promoter containing an array of three binding sites.

  10. The presence of different domains in 11 alternatively spliced isoforms of Gtf2ird1 indicates that the activity exerted by this molecule influences multiple promoters active in mouse skeletal muscle.

Human General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1) interaction partners

  1. The mis-regulation of genes downstream of GTF2IRD1, including TbetaR2 and BMPR1b, also individually promoted mammary cancer development, and silencing of TbetaR2 suppressed GTF2IRD1-driven tumor promotion.

  2. Study demonstrates a significant association between SLE in Chinese Han population and the GTF2I rs117026326 T allele/GTF2IRD1 rs4717901 C allele.

  3. GTF2IRD1 binding partners are mostly involved in chromatin modification and transcriptional regulation, whilst others indicate an unexpected role in connection with the primary cilium.

  4. GTF2IRD1 is SUMOylated by the SUMO E2 ligase UBC9 (show UBE2I Antibodies) and the level of SUMOylation is enhanced by PIASxbeta (show PIAS2 Antibodies).

  5. CLIP2 (show CLIP2 Antibodies) haploinsufficiency by itself does not lead to the physical or cognitive characteristics of the Williams-Beuren syndrome; GTF2IRD1 and GTF2I (show GTF2I Antibodies) are the main genes causing the cognitive defects

  6. This study provided evidences that insufficiency of GTF2IRD1 protein contributes to abnormalities of facial development, motor function and specific behavioural disorders that accompany Williams-Beuren syndrome.

  7. functional hemizygosity for the GTF2I and GTF2IRD1 genes is the main cause of the neurocognitive profile and some aspects of the gestalt phenotype of Williams-Beuren syndrome

  8. Data show the existence of a negative autoregulatory mechanism that controls the level of GTF2IRD1 transcription via direct binding of the GTF2IRD1 protein to a highly conserved region of the GTF2IRD1 promoter containing an array of three binding sites.

  9. characterization and involvement in slow muscle-specific (show EIF3K Antibodies) gene expression

  10. role as a repressor of slow fiber-specific transcription through mechanisms involving direct interactions with MEF2C (show MEF2C Antibodies) and the nuclear receptor co-repressor

GTF2IRD1 Antigen Profile

Protein Summary

The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with GTF2IRD1

  • GTF2I repeat domain containing 1 (GTF2IRD1) antibody
  • GTF2I repeat domain containing 1 (Gtf2ird1) antibody
  • general transcription factor II I repeat domain-containing 1 (Gtf2ird1) antibody
  • GTF2I repeat domain containing 1 (gtf2ird1) antibody
  • general transcription factor II-I repeat domain-containing protein 1 (LOC100461122) antibody
  • GTF2I repeat domain containing 1 S homeolog (gtf2ird1.S) antibody
  • 1700012P16Rik antibody
  • BEN antibody
  • cream1 antibody
  • ESTM9 antibody
  • Gtf2il antibody
  • GTF2IRD1 antibody
  • gtf3 antibody
  • hMusTRD1alpha1 antibody
  • mustrd1 antibody
  • rbap2 antibody
  • Tg(Alb1-Myc)166.8Sst antibody
  • wbs antibody
  • wbscr11 antibody
  • wbscr12 antibody
  • X83320 antibody
  • XBEN antibody
  • XWBSCR11 antibody

Protein level used designations for GTF2IRD1

general transcription factor II-I repeat domain-containing protein 1 , general transcription factor II I repeat domain-containing 1 , Alb-c-myc line 166.8 , Alb/c-myc line 166.8 , GTF2I repeat domain-containing 1 , GTF2I repeat domain-containing protein 1 , Williams-Beuren syndrome chromosome region 11 , binding factor for early enhancer , c-myc line 166.8 , general transcription factor 3 , muscle TFII-I repeat domain-containing protein 1 , transcription factor GTF3 alpha 2 , transcription factor GTF3 gamma 2 , GTF2I repeat domain containing 1 , USE B1-binding protein , general transcription factor III , muscle TFII-I repeat domain-containing protein 1 alpha 1 , slow-muscle-fiber enhancer-binding protein , williams-Beuren syndrome chromosomal region 12 protein , general transcription factor II-I repeat domain-containing protein 1-like , Binding factor for early enhancer , Williams-Beuren syndrome critical region 11-like protein

GENE ID SPECIES
507792 Bos taurus
246770 Rattus norvegicus
57080 Mus musculus
463471 Pan troglodytes
489796 Canis lupus familiaris
81597 Danio rerio
417487 Gallus gallus
693935 Macaca mulatta
9569 Homo sapiens
100461122 Pongo abelii
100473117 Ailuropoda melanoleuca
100510956 Sus scrofa
398320 Xenopus laevis
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