Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2 (GPT2) ELISA Kits

GPT2 encodes one of the two pyridoxal enzymes which catalyze a reversible transamination reaction to yield glutamate and pyruvate so these enzymes participate in amino acid metabolism and gluconeogenesis. Additionally we are shipping GPT2 Antibodies (71) and GPT2 Proteins (17) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GPT2 84706 Q8TD30
GPT2 307759  
GPT2 108682 Q8BGT5
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Top GPT2 ELISA Kits at antibodies-online.com

Showing 3 out of 9 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 0.78 ng/mL 1.56-100 ng/mL   96 Tests 2 to 3 Days
$713.90
Details
Mouse
  96 Tests 16 Days
$544.38
Details
Rat
  96 Tests 16 Days
$544.38
Details

More ELISA Kits for GPT2 Interaction Partners

Human Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2 (GPT2) interaction partners

  1. Because of the consistent presence of pyramidal tract affection in GPT2 patients, we further suggest that GPT2 mutations should be considered in cases with complex hereditary spastic paraplegia

  2. GPT2-related autosomal recessive intellectual disability represents an important new neurogenetic syndrome involving developmental as well as progressive features, notably motor disabilities

  3. We here describe novel compound heterozygous missense variants, NM_133443:c.[400C>T] and NM_133443:[1435G>A], in the glutamic-pyruvic transaminase 2 (GPT2) gene in a large consanguineous family with two affected siblings diagnosed with microcephaly intellectual disability and developmental delay (IDD).

  4. GPT2 reduced alpha-ketoglutarate level in cells leading to the inhibition of proline hydroxylase 2 (PHD2) activity involved in the regulation of HIF1alpha stability. Accumulation of HIF1alpha, resulting from GPT2-alpha-ketoglutarate-PHD2 axis, constitutively activates sonic hedgehog (Shh) signaling pathway.

  5. The GPT2 gene demonstrates increasing expression in brain in the early postnatal period, and GPT2 protein localizes to mitochondria. Akin to the human phenotype, Gpt2-null mice exhibit reduced brain growth. Through metabolomics and direct isotope tracing experiments, we find a number of metabolic abnormalities associated with loss of Gpt2

  6. Recessively inherited loss of function GPT2 mutations are a novel cause of intellectual disability.

  7. ATF4 silencing prevented the activating effect of histidinol and tunicamycin on ATF4 and ALT2 expression. Our findings point to ALT2 as an enzyme involved in the metabolic adaptation of the cell to stress

  8. expression of GPT2 especially in muscle and fat, suggests a unique and previously unrecognized role of this gene product in glucose, amino acid, and fatty acid metabolism and homeostasis.

  9. The biliary IL-6 and TNF-alpha levels were positively correlated with serum DBIL, TBA and gamma-GT levels in infantile hepatitis syndrome subjects.

  10. Elevation of liver enzymes and hepatic insulin resistance as reflected by fasting insulin occur in the early stages of insulin resistance and highlight the central role of the liver in insulin resistance in the general population.

  11. A clinical method for selective measurement of ALT1 and 2 in human plasma is described.

Mouse (Murine) Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2 (GPT2) interaction partners

  1. The GPT2 gene demonstrates increasing expression in brain in the early postnatal period, and GPT2 protein localizes to mitochondria. Akin to the human phenotype, Gpt2-null mice exhibit reduced brain growth. Through metabolomics and direct isotope tracing experiments, we find a number of metabolic abnormalities associated with loss of Gpt2

  2. Data suggest that Alt2/Gpt2 (but not Alt1/Gpt1) is induced in liver of obese mice (male ob/ob mice compared to lean C57BL/6J mice).

GPT2 Antigen Profile

Antigen Summary

This gene encodes one of the two pyridoxal enzymes which catalyze a reversible transamination reaction to yield glutamate and pyruvate so these enzymes participate in amino acid metabolism and gluconeogenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GPT2

  • glutamic--pyruvic transaminase 2 (GPT2) antibody
  • glutamic pyruvate transaminase (alanine aminotransferase) 2 L homeolog (gpt2.L) antibody
  • glutamic pyruvate transaminase (alanine aminotransferase) 2 (gpt2) antibody
  • alanine aminotransferase 2 (PTRG_06494) antibody
  • glutamic--pyruvic transaminase 2 (Gpt2) antibody
  • glutamic--pyruvic transaminase 2 (gpt2) antibody
  • glutamic pyruvate transaminase (alanine aminotransferase) 2 (Gpt2) antibody
  • 4631422C05Rik antibody
  • ALT2 antibody
  • AU014768 antibody
  • AU041193 antibody
  • C87201 antibody
  • Cc2-5 antibody
  • GPT2 antibody
  • im:7150662 antibody
  • sb:cb580 antibody
  • zgc:165657 antibody

Protein level used designations for GPT2

GPT 2 , alanine aminotransferase 2 , glutamate pyruvate transaminase 2 , glutamic--alanine transaminase 2 , glutamic--pyruvic transaminase 2 , glutamic-pyruvate transaminase 2 , glutamic pyruvate transaminase (alanine aminotransferase) 2 , ALT2 , glutamic pyruvate transaminase 2 , alanine aminotransferase 2-like

GENE ID SPECIES
84706 Homo sapiens
100056741 Equus caballus
618400 Bos taurus
444533 Xenopus laevis
415746 Gallus gallus
799963 Danio rerio
549559 Xenopus (Silurana) tropicalis
6344753 Pyrenophora tritici-repentis Pt-1C-BFP
307759 Rattus norvegicus
100521318 Sus scrofa
100550762 Meleagris gallopavo
100558944 Anolis carolinensis
100601247 Nomascus leucogenys
108682 Mus musculus
100724098 Cavia porcellus
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