More product categories related to Glutathione S-Transferase alpha 1 ELISA Kit
Top referenced Glutathione S-Transferase alpha 1 ELISA Kits
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Mouse (Murine) GSTA1 ELISA Kit for Sandwich ELISA - ABIN415557 : Ge, Chen, Yao, Zhou, Huang, Cai, Hei: Overexpression of Brg1 Alleviates Hepatic Ischemia/Reperfusion-Induced Acute Lung Injury through Antioxidative Stress Effects. in Oxidative medicine and cellular longevity 2018 (PubMed)
More ELISA Kits for Glutathione S-Transferase alpha 1 Interaction Partners
Human Glutathione S-Transferase alpha 1 (GSTA1) interaction partners
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Genotypes with lower or null activity of the GSTA1, GSTM1 or GSTT1 did not contribute independently to psoriasis susceptibility in our patients. However, we observed significant associations of genotype combinations with the risk of psoriasis development.
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For glutathione S-transferase alpha 1(GSTA1) and glutathione S-transferase mu 1(GSTM1) polymorphisms, an association was observed with dietary fiber intake
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With the use of siRNAs to compare the roles of GSTP1, GSTM2 and GSTA1 in three representative cisplatinresistant solid cancer cells, it is preliminarily concluded that GSTA predominates over the other two isozymes in the cisplatin resistance of the tested lungs, ovaries and stomach cancer cells.
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GSTA1 Expression Is Correlated With Aldosterone Level in KCNJ5-Mutated Adrenal Aldosterone-Producing Adenoma.
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Data (including data from studies using single-molecule fluorescence imaging) suggest that, for GSTA1, there are at least two conformations of the protein, consistent with model that ligand binding promotes closure of carboxy-terminal helix over active site; study involved binding of glutathione analogs and enzyme inhibitors.
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Combined GSTM1, GSTT1, GSTA1 and GSTP1 polymorphisms might be associated to the risk of clear cell renal cell carcinoma.
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Data show that the glutathione S-transferase alpha 1(GSTA1) TT genotype was more frequent in hepatocellular carcinoma (HCC) than in non-HCC patients, suggesting that individuals carrying this genotype could be associated with 2-fold higher risk of developing HCCs.
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Nrf-2 and Gst-a were more abundant in bone morrow of chronic myeloid leukemia(CML) patients compared with that of healthy donors. In addition, Nrf-2 and Gst-a were further up-regulated in samples of patients with weak response to IM. In conclusion, our study shows that rapid clearance of 4-HNE by Nrf-2/GST may represents a novel molecular basis of IM resistance in CML.
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Study found an association, although not statistically significant between GSTA1 gene variants and perioperative serum alpha-GST level, an indicator for liver hepatotoxicity.
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common polymorphisms in GSTA1, GSTM1 and GSTT1 are associated with susceptibility to bladder cancer in individuals from Balkan endemic nephropathy areas of Serbia.
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Data show that a higher concentration of fluoride in the saliva was detected in children with a higher glutathione S-transferase (GST) activity.
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polymorphisms not associated with bladder cancer susceptibility [meta-analysis]
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Influence of glutathione S-transferase gene polymorphisms on busulfan pharmacokinetics and outcome of hematopoietic stem-cell transplantation in thalassemia pediatric patients.
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The frequency of GSTA1, GSTM1 and GSTP1 genotypes was not significantly different between progressive myoclonus epilepsy patients and controls
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GSTA1 polymorphism is associated with different pregnancy-related conditions
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this is the first population pharmacokinetic study to suggest that GSTA1 polymorphisms in adults are associated with busulfan pharmacokinetics
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GST genotyping before hematopoietic stem cell transplantation may allow better prediction of busulfan pharmacokinetics and drug toxicity, and thereby improve outcome after busulfan and cyclophosphamide conditioning
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the differences of PK in BU among different ethnic groups existed because of the different distribution frequencies of GST gene polymorphism in Chinese patients and Caucasian patients.
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Data show that the distribution of the glutathione S-transferases alleles GSTA1*A/*B and GSTP1*A, *B, and *C in the Polish population correspond to the results of studies in Caucasians.
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Patients with a GSTA1*A heterozygous variant had a lower exposure to 4-hydroxycyclophosphamide (4OHCTX) during cyclophosphamide treatment of lupus nephritis compared to wild-type patients.
Mouse (Murine) Glutathione S-Transferase alpha 1 (GSTA1) interaction partners
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GSTA1 can be detected at the early stage of low concentration ethanol exposure and that GSTA1 is more sensitive and reliable marker in ethanol-induced hepatic injury.
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results suggest that GSTA1 can be detected at low concentrations during the early stages of acute hepatic injury and that GSTA1 is a more sensitive and more accurate indicator than ALT
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Report increased GSTA1 in airways of asthmatic mice.
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mitochondrial Gsta1 is induced under oxidative stress
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Exceptional activity of murine glutathione transferase A1-1 against (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene-induced DNA damage in stably transfected cells
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This is the first demonstration that heavy metals (mercury, lead and copper) regulate the expression of Gst ya gene through a transcriptional mechanism.
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Analysis of the expressed luciferase activity indicated that MMA activated the promoter 2.6-fold. MMA (from 1 to 30 mM) dose-dependently increased the promoter activity, which reached a plateau between 6 and 12 hrs.
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Essential roles of ERKs and p38K in up-regulation of GST A1 expression by Maotai content in human hepatoma cell line Hep3B.It is widely accepted that the consumption of alcohol may lead to hepatic injuries such as hepatic fibrosis and cirrhosis.
Pig (Porcine) Glutathione S-Transferase alpha 1 (GSTA1) interaction partners
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cloning and characteristics of GSTA1-1
Glutathione S-Transferase alpha 1 (GSTA1) Antigen Profile
Antigen Summary
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
Gene names and symbols associated with GSTA1
- glutathione S-transferase alpha 1 (GSTA1) antibody
- glutathione S-transferase, alpha 1 (Ya) (Gsta1) antibody
- glutathione S-transferase alpha 5 (GSTA5) antibody
- glutathione S-transferase alpha 3 (GSTA3) antibody
- glutathione S-transferase alpha 1 L homeolog (gsta1.L) antibody
- glutathione S-transferase alpha 1 (gsta1) antibody
- glutathione S-transferase alpha 2 (Gsta2) antibody
- glutathione S-transferase mu 2 (muscle) (GSTM2) antibody
- Glutathione S-transferase 2 (gst-2) antibody
- glutathione S-transferase A (LOC100713029) antibody
- glutathione S-transferase Gst2 (gst2) antibody
- glutathione S-transferase 2 (LOC101897277) antibody
- Gst-2 antibody
- Gst-3 antibody
- Gst2 antibody
- Gst2-1 antibody
- Gst3 antibody
- Gsta1 antibody
- gsta1-1 antibody
- gth1 antibody
- OTTMUSG00000031890 antibody
Protein level used designations for GSTA1
GST HA subunit 1 , GST class-alpha member 1 , GST, class alpha, 1 , GST-epsilon , S-(hydroxyalkyl)glutathione lyase A1 , glutathione S-alkyltransferase A1 , glutathione S-aryltransferase A1 , glutathione S-transferase 2 , glutathione S-transferase A1 , glutathione S-transferase Ha subunit 1 , glutathione S-transferase Ya , glutathione S-transferase Ya1 , glutathione S-transferase alpha 1 , glutathione S-transferase alpha-1 , GST class-alpha , glutathione S-transferase alpha M14 , GST 1-1 , GST 1a-1a , GST A1-1 , GST B , GST Ya1 , Glutathione-S-transferase alpha type (Yc?) , glutathione S-transferase A2 , glutathione S-transferase Ya subunit , glutathione S-transferase Ya-1 , glutathione-S-transferase, alpha type2 , ligandin , GST class-mu , GST-CL2 , GSTM1-1 , glutathione S-transferases CL2 , GST-II , GST class-theta , Glutathione S-transferase 3 , glutatione transferase-2 , glutatione transferase-3C
GENE ID | SPECIES |
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2938 | Homo sapiens |
14857 | Mus musculus |
741887 | Pan troglodytes |
777644 | Bos taurus |
100141301 | Ovis aries |
397682 | Sus scrofa |
100036921 | Xenopus laevis |
100127839 | Xenopus (Silurana) tropicalis |
24422 | Rattus norvegicus |
395976 | Gallus gallus |
177884 | Caenorhabditis elegans |
100713029 | Cavia porcellus |
2539601 | Schizosaccharomyces pombe 972h- |
101897277 | Musca domestica |
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