Glycophorin B (MNS Blood Group) Proteins (GYPB)

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. Additionally we are shipping Glycophorin B (MNS Blood Group) Antibodies (37) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GYPB 2994 P06028
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Top Glycophorin B (MNS Blood Group) Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
Wheat germ Human Un-conjugated   2 μg Log in to see 11 to 12 Days
Wheat germ Human GST tag   10 μg Log in to see 11 to 12 Days

GYPB Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Glycophorin B (MNS Blood Group) (GYPB) Interaction Partners

Human Glycophorin B (MNS Blood Group) (GYPB) interaction partners

  1. a complex structural rearrangement involving the loss of GYPB and gain of two GYPB-A hybrid genes reduces the risk of severe malaria by 40% and has recently increased in frequency in parts of Kenya

  2. through bioinformatic analysis, identified extensive variation in GYPB transcript levels in individuals from Benin, suggesting selection from malaria pressure; collective data suggest that the GPA (show GYPA Proteins) and GPB receptors are of greater importance than the GPC (show GYPC Proteins) receptor, supporting a hierarchy of erythrocyte receptor (show CD2 Proteins) usage in P. falciparum

  3. MNSs blood group (show DARC Proteins) glycophorin variants in Taiwan: a genotype-serotype correlation study of 'Mi(a)' and St(a) with report of two new alleles for St(a).

  4. A novel GYPB mutation (c.270+5G>A) accounting for the S-s-U+(var) phenotype was identified.

  5. Substitution of GPB with Gp.Mur significantly reduced the expression of Rh antigen and RhAG (show RHAG Proteins) on the Mi.III(+/+) erythrocyte membrane

  6. an increased susceptibility to infection by this parasite is associated with the glycophorin B S+ variant in Brazilian Amazons

  7. Indochina I strain of P. falciparum is not dependent on glycophorin B to invade erythrocytse through a trypsin-resistant pathway as are the strains 3D7, HB3, and Dd2.

  8. The S-s-U+var phenotype arises from changes in or around GYPB exon 5.

  9. GYPA (show GYPA Proteins) & GYPB genotypes carrying MNSs antigens were analyzed in Thai patients with cerebral malaria & mild malaria; no statistical difference was found; it is concluded that MNSs antigens do not reveal the difference in susceptibility to cerebral malaria

  10. Alternative to conventional tube technique for mass screening for MNS hybrids, especially when specific antisera are not available.

Glycophorin B (MNS Blood Group) (GYPB) Protein Profile

Protein Summary

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta\\\\; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB.

Gene names and symbols associated with GYPB

  • glycophorin B (MNS blood group) (GYPB)
  • CD235b protein
  • GPB protein
  • GPB.NY protein
  • GpMiIII protein
  • GYPHe.NY protein
  • HGpMiIII protein
  • HGpMiVI protein
  • HGpMiX protein
  • MNS protein
  • PAS-3 protein
  • SS protein

Protein level used designations for GYPB

SS-active sialoglycoprotein , Ss blood group , glycophorin HeP2 , glycophorin MiIII , glycophorin MiVI , glycophorin MiX , glycophorin-B , sialoglycoprotein delta

2994 Homo sapiens
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