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GPM6B encodes a membrane glycoprotein that belongs to the proteolipid protein family. Additionally we are shipping GPM6B Antibodies (44) and GPM6B Kits (4) and many more products for this protein.
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Data indicate that neuronal membrane glycoproteins GPM6A and GPM6B may act as novel oncogenes in the development of lymphoid leukemia.
Increase in the expression levels of mRNA and protein for the Gpm6B is associated with various types of gynaecological malignancy.
Circulating levels of DR6 and Gpm6B correlate with breast cancer tumor grade.
Data show the Differences in high resolution melting analysis in promoters of tumor markers neuronal membrane glycoprotein M6-B, melanoma antigen family A12 and immunoglobulin superfamily Fc receptor indicated invasiveness of hepatocellular carcinoma.
Microarray expression analysis of GPM6B-depleted osteogenic human mesenchymal stem cells revealed significant changes in genes involved in cytoskeleton organization and biogenesis.
it is unlikely that mutations in M6B have a role in Pelizaeus-Merzbacher-like syndrome, as examined in eight patients
Data suggest that M6B regulates serotonin uptake by affecting cellular trafficking of the serotonin transporter.
Study identified glycoprotein M6B as a Schwann cell microvilli component of peripheral nodes of Ranvier. Study detected Na(+) channel clusters at heminodes without any associated M6B, indicating that it is not required for initial channel clustering; showed that absence of M6B results in progressive appearance of nodal protrusions of the nodal axolemma, that are often accompanied by the presence of enlarged mitochondria.
The results of this study proposed that M6b proteins are required for proper extension and guidance of callosal axons that follow one of the most complex trajectories in the mammalian nervous system.
M6B is not efficiently sorted into mature myelin, in which it is 200-fold less abundant than proteolipid protein (PLP).
This gene encodes a membrane glycoprotein that belongs to the proteolipid protein family. Proteolipid protein family members are expressed in most brain regions and are thought to be involved in cellular housekeeping functions, such as membrane trafficking and cell-to-cell communication.
neuronal membrane glycoprotein M6-b
, protolipid M6B
, rhombencephalic expression protein-29 kDa
, proteolipid GPM6B
, glycoprotein M6B
, glycoprotein M6B S homeolog
, myelin PLP-related membrane protein DM gamma1
, glycoprotein M6Ba