GP6 encodes a platelet membrane glycoprotein of the immunoglobulin superfamily.
GP6 Protein Profile
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene names and symbols associated with GP6
glycoprotein VI platelet (GP6) antibody
glycoprotein 6 (platelet) (Gp6) antibody
glycoprotein VI (Gp6) antibody
glycoprotein VI platelet (Gp6) antibody
platelet glycoprotein VI (LOC103346235) antibody
Protein level used designations for GP6
, platelet collagen receptor
, platelet glycoprotein VI
, glycoprotein VI (platelet)
, glycoprotein 5
, glycoprotein 6 (platelet)
, glycoprotein VI