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GOSR1 encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi and between Golgi compartments.
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Data indicate that mutations in Golgi SNARE (show GOSR2 Antibodies) protein gos28 lead to defective rhodopsin (Rh1 (show RHO Antibodies)) trafficking.
these results indicate that GS28 nuclear predominant expression could serve as a prognostic marker for colorectal cancer (CRC (show CALR Antibodies)) and may help in identifying aggressive forms of CRC (show CALR Antibodies)
High nuclear expression of GS28 is associated with poor prognosis in early-stage cervical cancer patients. GS28 might be a novel prognostic marker and a potential therapeutic target in cervical cancer treatment.
Golgi vesicles, presumably with COPI, serve to inhibit intra-Golgi transport by the extraction of GS27 (show GOSR2 Antibodies) and GS28 from the Golgi cisternae, which blocks the formation of inter-cisternal connections
GS28 may potentiate cells to DNA-damage-induced apoptosis by inhibiting the ubiquitination and degradation of p53 (show TP53 Antibodies).
ORP7 (show OSBPL7 Antibodies) negatively regulates GS28 protein stability via sequestration of GATE-16 (show GABARAPL2 Antibodies), and may mediate the effect of 25-OH on GS28 and Golgi function.
Apolipoprotein E (show APOE Antibodies), growth factor receptor-bound protein 2 (show GRB2 Antibodies), Golgi SNAP receptor complex member 1, and glucosidase, beta, acid may play a neurodegenerative role in stress urinary incontinence development.
Data suggest that GS15 (show BET1L Antibodies) exists in a distinct SNARE (show NAPA Antibodies) complex that contains syntaxin5 (show STX5 Antibodies), GS28, and Ykt6 (show YKT6 Antibodies), and may be involved in both ER-to-Golgi and intra-Golgi transport.
RINT-1 (show RINT1 Antibodies) coordinates the localization and function of ZW10 (show ZW10 Antibodies) by serving as a link between ZW10 (show ZW10 Antibodies) and the SNARE (show NAPA Antibodies) complex comprising syntaxin 18 (show STX18 Antibodies).
This gene encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi and between Golgi compartments. This protein is considered an essential component of the Golgi SNAP receptor (SNARE) complex. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
, Golgi SNAP receptor complex member 1
, golgi SNAP receptor complex member 1
, 28 kDa Golgi SNARE protein
, 28 kDa cis-Golgi SNARE p28
, Golgi SNARE 28 kDa
, cis-golgi SNARE
, golgi integral membrane protein 2
, Cis-Golgi SNARE
, cis-Golgi p28 (p28)