anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) Antibodies

GNRHR encodes the receptor for type 1 gonadotropin-releasing hormone. Additionally we are shipping GNRHR Kits (32) and GNRHR Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GNRHR 2798 P30968
GNRHR 14715 Q01776
GNRHR 81668 P30969
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Top anti-GNRHR Antibodies at antibodies-online.com

Showing 10 out of 126 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN334412 (0.5µg/ml) staining of Human Peripheral Blood Mononucleocyte lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Goat Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat submandibular gland labeled with Anti-GnRHR Polyclonal Antibody, Unconjugated followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Anti-GnRHR Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$318.45
Details
Mouse Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of A549 cells, using GNRHR Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated EIA, IHC (fro), WB   0.1 mg Log in to see 6 to 8 Days
$368.50
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-GNRHR antibody IHC of human pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Dog Goat Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$610.50
Details
Rat Rabbit Un-conjugated IHC, WB Western blot analysis of rat ovary (lanes 1 and 3) and rat pituitary (lanes 2 and 4) lysates: 1, 2. Anti-GnRH Receptor (extracellular) antibody, (1:200). 3, 4. Anti-GnRH Receptor (extracellular) antibody, preincubated with the control peptide antigen. Expression of GnRH in rat ovary Immunohistochemical staining of rat ovary paraffin-embedded sections using Anti-GnRH Receptor (extracellular) antibody. GnRHR labeling appears in the stroma surrounding the follicles. The stroma is a richly cellular connective tissue with scattered smooth muscle fibers. The Theca layer is stained as well. Hematoxilin is used as the counterstain. 0.2 mL Log in to see 10 to 11 Days
$832.43
Details
Human Goat Un-conjugated ELISA, WB ABIN188695 (0.5?g/ml) staining of Human Peripheral Blood Mononucleocyte lysate (35?g protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated WB GNRHR Antibody (N-term)  western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the GNRHR  Antibody detected the GNRHR  protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Goat Un-conjugated EIA, WB   0.1 mg Log in to see 8 to 11 Days
$462.00
Details

Top referenced anti-GNRHR Antibodies

  1. Human Monoclonal GNRHR Primary Antibody for IHC (fro), FACS - ABIN966217 : Karande, Rajeshwari, Schol, Hilgers: Establishment of immunological probes to study human gonadotropin-releasing hormone receptors. in Molecular and cellular endocrinology 1996 (PubMed)
    Show all 5 Pubmed References

  2. Goat Polyclonal GNRHR Primary Antibody for IF (p), IHC (p) - ABIN686917 : Liu, Li, Zhu, Yu, Guo, Zhou, Zheng, Qu, Huang, Chen, Wang, Ye: Effects of di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-ovarian axis in adult female rats. in Reproductive toxicology (Elmsford, N.Y.) 2014 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal GNRHR Primary Antibody for ELISA, WB - ABIN188695 : Yeung, An, Cheng, Chow, Leung: Expression and transcriptional regulation of the GnRH receptor gene in human neuronal cells. in Molecular human reproduction 2006 (PubMed)

More Antibodies against GNRHR Interaction Partners

Human Gonadotropin-Releasing Hormone Receptor (GNRHR) interaction partners

  1. c.364C>T in GNRHR is a complete loss-of-function mutation which caused idiopathic hypogonadotropic hypogonadism.

  2. GNRHR (and GNRH) are expressed in trophoblast cell populations and fallopian tube epithelium at tubal ectopic pregnancy sites.

  3. first description of a GNRHR gene mutation in three patients diagnosed with polycystic ovary syndrome.

  4. We showed that GNRHR and LHCGR were highly expressed in some wildtype aldosterone-producing adenoma samples, and that they positively correlated with GnRH-stimulated aldosterone production.

  5. Results show that biallelic gonadotropin releasing hormone receptor (GNRHR) mutations are not a frequent cause of age-related androgen decline in men.

  6. GnRH receptors on triple negative breast cancer cells can be used for targeted therapy of these cancers with GnRH agonist triptorelin

  7. study found a novel mutation in PROK2 (show PROK2 Antibodies) in two male siblings presenting normosmic congenital hypogonadotropic hypogonadism, in whom a mutation in the GNRHR gene had been previously described, suggesting the possibility of a digenic inheritance

  8. Data suggest differences in regulation of expression of PEDF (show SERPINF1 Antibodies) (up-regulation) vs. VEGF (show VEGFA Antibodies) (down-regulation) in granulosa cells explain reduced risk of ovarian hyperstimulation syndrome due to ovulation induction using GnRH (show GNRH1 Antibodies)/GNRHR agonists rather than hCG (show CGA Antibodies).

  9. A high prevalence of endometriosis, polymorphism in the LHCGR and GnRH1 and progonadoliberin-2 antibodies in serum was found among the patients with severe dysmotility after treatment with GnRH analogs.

  10. No abnormalities were found in the patient group for the PROKR2 (show PROKR2 Antibodies) and GNRH1genes. In addition, no genomic rearrangements were identified in the healthy control individuals for the described genes

Rabbit Gonadotropin-Releasing Hormone Receptor (GNRHR) interaction partners

  1. These results suggest that GNRHR-I is constitutively expressed in rabbit corpora lutea independently of luteal stage of pseudopregnant rabbits.

Mouse (Murine) Gonadotropin-Releasing Hormone Receptor (GNRHR) interaction partners

  1. leptin's direct stimulatory actions on gonadotrope GnRHR correlate with a direct inhibition of expression of the posttranscriptional regulator MSI1 (show MSI1 Antibodies). There also is a direct MSI1 (show MSI1 Antibodies) interaction with 3'-UTR (show UTS2R Antibodies) of Gnrhr mRNA.

  2. the age-dependent basal and regulated Gnrhr transcription could account for the initial blockade and subsequent activation of the reproductive system during development.

  3. GnRH (show GNRH1 Antibodies)-GnRHR system is not essential for growth or motor/sensory/orientation behavior during the first month of life prior to puberty onset. The lack of the GnRH (show GNRH1 Antibodies)-GnRHR axis, however, did affect females resulting in reduced subcutaneous inguinal fat pad (show DHX40 Antibodies) weight and increased glucose with possible insulin (show INS Antibodies) resistance.

  4. His305 of the GnRH receptor forms two distinct interactions that determine binding to GnRH and couple agonist binding to the conserved transmembrane domain network that activates GPCRs.

  5. The aims of this study were to explore whether mRNA-levels of gonadotropin-releasing hormone (Gnrh (show GNRH1 Antibodies)) and its receptor (Gnrhr) were changed in plaque-bearing Alzheimer's disease transgenic mice.

  6. Data confirm that Gnrhr mRNA and protein are expressed in ovaries, granulosa cells, cumulus cells, and oocytes.

  7. Msx1 (show MSX1 Antibodies) functions as a negative regulator early in pituitary development by repressing the gonadotrope-specific alphaGSU (show CGA Antibodies) and GnRHR genes.

  8. These results suggest decreased GnRH receptor signaling in the mutant animal, compared with wild type.

  9. Report down-regulation of ErbB4 (show ERBB4 Antibodies) expression in hypothalamic neurons induced by G-protein-coupled gonadotropin releasing hormone receptor stimulation.

  10. GnRHR neurons were found in different brain areas. Many GnRHR neurons were identified in areas influencing sexual behaviors

Cow (Bovine) Gonadotropin-Releasing Hormone Receptor (GNRHR) interaction partners

  1. The GRIA1 (show GRIA1 Antibodies) polymorphism exists in beef cows but it does not influence antral follicle numbers. The association between GnRHR genotype and age at first calving is likely not causal as this polymorphism is not functional.

  2. There was a significant correlation between frequency profile and timing of puberty among the studied breeds, which seems to suggest that genetic variation within bovine GNRHR gene could explain at least part of the reported variability.

  3. These results indicate that GnRHR gene can be a potential marker for improving sperm quality traits, and imply that bulls with GA or CT genotype should be selected in breeding program.

  4. Seven sequence variants (SVs) have been identified in exon 1 and in the promoter region upstream of the bovine gonadotrophin releasing hormone (GnRH) receptor; g.-108T>C alteration was associated with beneficial effects on fertility

Rainbow Trout (Oncorhynchus mykiss) Gonadotropin-Releasing Hormone Receptor (GNRHR) interaction partners

  1. Data show that GnRH (show GNRH1 Antibodies) stimulates phagocytosis in fish leucocytes through a GnRH-receptor-dependent pathway.

GNRHR Antigen Profile

Protein Summary

This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.

Gene names and symbols associated with GNRHR

  • gonadotropin releasing hormone receptor (GNRHR) antibody
  • gonadotropin releasing hormone receptor (Gnrhr) antibody
  • gonadotropin releasing hormone receptor (gnrhr) antibody
  • gonadotropin-releasing hormone receptor (gnrh-r) antibody
  • GH1 antibody
  • gnrh-r antibody
  • GNRHR antibody
  • GNRHR1 antibody
  • GNRHR1/III antibody
  • GNRHR2 antibody
  • gnrhr3/ii antibody
  • GRHR antibody
  • HH7 antibody
  • Lhrhr antibody
  • LRHR antibody
  • xgnrhr antibody

Protein level used designations for GNRHR

gnRH receptor , gnRH-R , gonadotropin-releasing hormone (type 1) receptor 1 , leutinizing hormone releasing horomone receptor , leutinizing-releasing hormone receptor , luliberin receptor , type I GnRH receptor , GnRH receptor , gonadotropin-releasing hormone receptor , gonadotropin releasing hormone receptor , growth hormone , luteinizing-releasing hormone receptor , gnoadotropin releasing hormone receptor 2 , gonadotropin-releasing hormone II receptor , type 1/III gonadotropin-releasing hormone receptor hexahelical , type 3/II gonadotropin-releasing hormone receptor , pituitary GnRH receptor , pituitary gonadotropin-releasing hormone receptor , LHRH , luteinizing hormone-releasing hormone receptor

GENE ID SPECIES
2798 Homo sapiens
403718 Canis lupus familiaris
443413 Ovis aries
471226 Pan troglodytes
711577 Macaca mulatta
100009509 Oryctolagus cuniculus
100093333 Ornithorhynchus anatinus
100135532 Cavia porcellus
100589627 Nomascus leucogenys
14715 Mus musculus
81668 Rattus norvegicus
281798 Bos taurus
427517 Gallus gallus
100135417 Xenopus (Silurana) tropicalis
100136028 Oncorhynchus mykiss
100033874 Equus caballus
397515 Sus scrofa
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