Granzyme K (Granzyme 3, Tryptase II) (GZMK) ELISA Kits

GZMK product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Additionally we are shipping Granzyme K (Granzyme 3, Tryptase II) Antibodies (90) and Granzyme K (Granzyme 3, Tryptase II) Proteins (13) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GZMK 14945 O35205
GZMK 29165 P49864
GZMK 3003 P49863
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Top Granzyme K (Granzyme 3, Tryptase II) ELISA Kits at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 2.41 pg/mL 15.63-1000 pg/mL 96 Tests 3 to 4 Days
$390.31
Details
Mouse 6.2 pg/mL 15.6 pg/mL - 1000 pg/mL 96 Tests 13 to 16 Days
$720.00
Details
Rat 9.375 pg/mL 15.63 pg/mL - 1000 pg/mL A typical standard curve 96 Tests 13 to 16 Days
$601.54
Details
Pig 18.75 pg/mL 31.25-2000 pg/mL   96 Tests 12 to 14 Days
$715.00
Details
Chicken 37.5 pg/mL 62.5-4000 pg/mL   96 Tests 12 to 14 Days
$715.00
Details
Guinea Pig 18.75 pg/mL 31.25-2000 pg/mL   96 Tests 12 to 14 Days
$715.00
Details
Rabbit 0.094 ng/mL 0.156-10 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Monkey 18.75 pg/mL 31.25-2000 pg/mL   96 Tests 12 to 14 Days
$715.00
Details
Human 7.5 pg/mL 12.5 pg/mL - 800 pg/mL Typical standard curve 96 Tests 12 to 14 Days
$715.00
Details
Rat 4.688 pg/mL 7.813 pg/mL - 500 pg/mL Typical standard curve 96 Tests 12 to 14 Days
$715.00
Details

More ELISA Kits for Granzyme K (Granzyme 3, Tryptase II) Interaction Partners

Mouse (Murine) Granzyme K (Granzyme 3, Tryptase II) (GZMK) interaction partners

  1. these data suggest that granzyme K does not play an essential role in viral immunity or cytotoxicity

  2. Data indicate N-terminomics on the human and mouse granzymes A and K by combined fractional diagonal chromatography (COFRADIC).

  3. The data suggest that T-killer cells control lymphocytic choriomeningitis virus through non-cytotoxic processes that involve gzmK.

  4. It was suggested that a high predisposition to catalepsy in mice can be defined by the Map3k1, Il6st, Gzmk, and Hspb3 genes' coexpression network.

  5. GzmK-induced caspase-independent death occurs through Bid-dependent mitochondrial damage that is different from GzmA

  6. grzK plays an important role in CD8(+) T-cell cytotoxicity both in the presence and absence of grzA and B.

Human Granzyme K (Granzyme 3, Tryptase II) (GZMK) interaction partners

  1. Extracellular granzyme K mediates endothelial activation through the cleavage of PAR-1.

  2. Carbamate pesticides significantly reduced the intracellular levels of perforin, GrA, GrB, Gr3/K, and GRN in NK-92CI cells.

  3. Data indicate N-terminomics on the human and mouse granzymes A and K by combined fractional diagonal chromatography (COFRADIC).

  4. Extracellular GrK is an unexpected direct modulator of lipopolysaccharide-TLR4 signaling during the antimicrobial innate immune response.

  5. Granzyme K plays an important physiological role in immunoregulation of adaptive immunity underlying the cytotoxicity of CD56(bright) natural killer (NK) cells toward activated T cells.

  6. Gr3 proenzymes is activated by cathepsin C which concomitantly decreased the molecular weight to that of active Gr3.

  7. The 2.2-A crystal structure reveals a rigid zymogen with unusual features

  8. The present findings thus introduce the possibility that human beta-tryptase, after mast cell degranulation and exposure to neutral pH in the tissue, may dissociate into active monomers with properties that are distinct from the tetrameric counterpart.

  9. We found human GzmK triggers rapid cell death independently of caspase activation. The features of death are characterized by rapid externalization of phosphatidylserine, nuclear morphological changes and single-stranded DNA nicks.

  10. GzmK-induced caspase-independent death occurs through Bid-dependent mitochondrial damage that is different from GzmA

  11. Rsults indicate that plasma levels of Granzyme K could serve as a useful diagnostic marker to stage sepsis, permitting better classification, specific treatments of patients, and may play a functional role in the development of sepsis.

  12. GrK not only constitutes a redundant functional backup mechanism that assists GrA-induced cell death but that it also displays a unique function by cleaving its own specific substrates.

  13. p53 is as a cytotoxic bomb that can be triggered by granzyme K, leading to potentiating killing efficacy.

Rabbit Granzyme K (Granzyme 3, Tryptase II) (GZMK) interaction partners

  1. Data show that the serum levels of mast cell tryptase, monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) decreased significantly in Dachengqi decoction treatment group.

Granzyme K (Granzyme 3, Tryptase II) (GZMK) Antigen Profile

Antigen Summary

This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.

Gene names and symbols associated with GZMK

  • granzyme K (GZMK) antibody
  • granzyme K (Gzmk) antibody
  • TRYP2 antibody

Protein level used designations for GZMK

NK-Tryp-2 , NK-tryptase-2 , RNK-Tryp-2 , fragmentin-3 , granzyme 3 , granzyme K , granzyme K (serine protease, granzyme 3; tryptase II) , granzyme-3 , tryptase II

GENE ID SPECIES
100052126 Equus caballus
14945 Mus musculus
29165 Rattus norvegicus
3003 Homo sapiens
100233185 Sus scrofa
426168 Gallus gallus
100727863 Cavia porcellus
100345938 Oryctolagus cuniculus
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