anti-Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) Antibodies

GADD45GIP1 encodes a nuclear-localized protein that may be induced by p53 and regulates the cell cycle by inhibiting G1 to S phase progression. Additionally we are shipping Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 Proteins (7) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GADD45GIP1 90480 Q8TAE8
GADD45GIP1 102060 Q9CR59
GADD45GIP1 288916 Q5XJW2
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Top anti-Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of CRIF1 expression in HeLa (A), NS-1 (B), PC12 (C) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using GADD45GIP1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p) 100 μL 11 to 14 Days
$493.17
Details
Dog Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated FACS, WB Flow cytometric analysis of MCF-7 cells using GADD45GIP1 Antibody (N-term)(green) compared to an isotype control of rabbit IgG(blue). Antibody was diluted at 1:25 dilution. An Alexa Fluor 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody. Western blot analysis of lysate from 293 cell line, using GADD45GIP1 Antibody at 1:1000. 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μL Available
$363.46
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of extracts of K-562 cells, using GADD45GIP1 antibody (ABIN5972935). 100 μL 11 to 16 Days
$426.40
Details
Human Mouse Un-conjugated WB Western Blot analysis of GADD45GIP1 expression in transfected 293T cell line by GADD45GIP1 MaxPab polyclonal antibody.Lane 1: GADD45GIP1 transfected lysate(24.42 KDa).Lane 2: Non-transfected lysate. GADD45GIP1 MaxPab polyclonal antibody. Western Blot analysis of GADD45GIP1 expression in A-431. 50 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$375.83
Details

More Antibodies against Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 Interaction Partners

Human Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) interaction partners

  1. NRF2 Ser40 phosphorylation was inhibited in Crif1-deficient bone marrow multipotent mesenchymal stromal cells even in the presence of three kinds of PKC agonists, suggesting that CRIF1 might co-activate PKC-delta to phosphorylate NRF2 Ser40.

  2. strongly suggest that CRIF1 deficiency promotes endothelial cell inflammation by increasing VCAM-1 expression, elevating inflammatory cytokines levels, and activating the transcription factor NF-kappaB, all of which were inhibited by SIRT1 overexpression

  3. Results demonstrate that knockdown of CRIF1 in HUVECs induces mitochondrial dysfunction and reduces SIRT1 expression along with decreased eNOS phosphorylation and increased eNOS acetylation, thereby promoting endothelial dysfunction. These findings indicate that CRIF1 plays an important role in maintaining mitochondrial and endothelial function through its effects on the SIRT1-eNOS pathway.

  4. SNF5 is indispensable for CRIF1-enhanced p53 activity and its function in the suppression of cell cycle arrest in human cancer cells.

  5. Study shows that Lck interacts with CRIF1 in the mitochondria and negatively regulates CRIF1-mediated translation of mitochondrion-encoded proteins.

  6. our results support a novel function of nuclear Lck in promoting human leukemic T cell survival through interaction with a tumor suppressor, CRIF1

  7. Crif1 is an indispensable regulator of PKAalpha cat that modulates the PKA/CREB signaling pathway to promote adipogenic differentiation of bone marrow mesenchymal stem cells after irradiation

  8. The results identify the ROS-Sp1-Crif1 pathway to be a new mechanism underlying Abeta-induced mitochondrial dysfunction and suggest that ROS-mediated downregulation of Crif1 is a crucial event in AD pathology.

  9. CRIF1 knockdown partially induces endothelial activation via increased ROS production and phosphorylation of p66shc

  10. CRIF1 may play a regulatory role in the BM microenvironment-induced leukemia cell cycle arrest possibly through interacting with CDK2 and acting as a cyclin-dependent kinase inhibitor.

  11. CKbetaBP2/CRIF1 is expressed with STAT3 in prostate cancer where STAT3 may help to offset the AR repressor effect of CKbetaBP2/CRIF1.

  12. results indicated cell cycle arrest of Jurkat cells in the G0/G1 phase to be induced by primary cultured leukemic BMSCs associated with increased expression of CRIF1 by leukemic cells

  13. CRIF1, unlike KEAP1 (which only interacts with N-terminal region of NRF2), physically interacts with both N- and C-terminal regions of NRF2 and promotes NRF2 ubiquitination and subsequent proteasome-mediated NRF2 protein degradation

  14. results suggest that CRIF1 is a novel nuclear protein that interacts with Gadd45 and may play a role in negative regulation of cell cycle progression and cell growth

  15. Phosphorylation of serine-221 in CKBBP2/CRIF1 promotes proliferation of green monkey COS7 cells.

  16. NAC-1 contributes to tumor growth and survival by at least inhibiting Gadd45GIP1 expression, which has a tumor suppressor effect in cancer cells.

  17. Results suggest that CRIF1 acts as an AR corepressor and may play an important role in the regulation of AR-positive growth of prostate cancer.

Mouse (Murine) Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) interaction partners

  1. To investigate the impact of loss of CRIF1 in T cells, we generated a conditional CRIF1 gene ablation model using CD4-cre transgenic mice and examined the frequency of Th17 cells and regulatory T cells.

  2. Crif1(beta-/-) mouse is a useful model for the study of beta cell failure caused by mitochondrial OxPhos dysfunction.

  3. The results identify the ROS-Sp1-Crif1 pathway to be a new mechanism underlying Abeta-induced mitochondrial dysfunction and suggest that ROS-mediated downregulation of Crif1 is a crucial event in AD pathology.

  4. CRIF1 knockdown partially induces endothelial activation via increased ROS production and phosphorylation of p66shc

  5. Study showed that loss of Crif1 impairs mitochondrial oxidative phosphorylation and adipocyte differentiation in vitro and in vivo.

  6. Crif1 plays a critical role in the maintenance of both mitochondrial structure and respiration in cardiac muscles.

  7. Although adipose-specific Crif1-haploinsufficient mice showed normal growth and development, they became insulin-resistant.

  8. CRIF1 is essential for the synthesis and insertion of oxidative phosphorylation polypeptides in the mammalian mitochondrial membrane.

  9. Results reveal that Crif1 is a novel and essential transcriptional coactivator of Elf3 for the terminal differentiation of absorptive enterocytes.

  10. Crif1 is a novel and essential transcriptional coactivator of STAT3 that modulates its DNA binding ability.

Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) Antigen Profile

Protein Summary

This gene encodes a nuclear-localized protein that may be induced by p53 and regulates the cell cycle by inhibiting G1 to S phase progression. The encoded protein may interact with other cell cycle regulators.

Gene names and symbols associated with GADD45GIP1

  • growth arrest and DNA-damage-inducible, gamma interacting protein 1 (gadd45gip1) antibody
  • GADD45G interacting protein 1 (GADD45GIP1) antibody
  • growth arrest and DNA-damage-inducible, gamma interacting protein 1 (Gadd45gip1) antibody
  • GADD45G interacting protein 1 (Gadd45gip1) antibody
  • 2310040G17Rik antibody
  • AI425883 antibody
  • CKBBP2 antibody
  • Crif1 antibody
  • PLINP antibody
  • PLINP-1 antibody
  • Plinp1 antibody
  • PRG6 antibody
  • si:dkey-194e13.6 antibody

Protein level used designations for GADD45GIP1

CKII beta binding protein 2 , CKII beta-associating protein , CR6 interacting factor 1 , growth arrest and DNA damage-inducible proteins-interacting protein 1 , growth arrest- and DNA damage-inducible GADD45G-interacting protein , p53-responsive gene 6 protein , papillomavirus L2 interacting nuclear protein 1 , growth arrest and DNA-damage-inducible proteins-interacting protein 1

GENE ID SPECIES
402803 Danio rerio
90480 Homo sapiens
102060 Mus musculus
288916 Rattus norvegicus
504718 Bos taurus
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