Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) (Middle Region) antibody

Details for Product No. ABIN2789108
Target
Binding Specificity
Middle Region
2
2
1
1
1
1
1
1
1
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Saccharomyces cerevisiae
19
5
4
1
1
1
Host
Rabbit
17
2
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
1
Application
Western Blotting (WB)
11
5
2
2
2
1
1
Options
Blocking Peptide Blocking peptide for this product available: ABIN977233
Sequence SLRVKQLAEE QKRREREQHI AECMAKMPQM IVNWQQQQRE NWEKAQADKE
Predicted Reactivity Cow: 90%, Dog: 90%, Guinea Pig: 85%, Horse: 90%, Human: 100%, Mouse: 90%, Pig: 92%, Rabbit: 85%, Rat: 92%, Yeast: 91%
Characteristics This is a rabbit polyclonal antibody against GADD45GIP1. It was validated on Western Blot.
Purification Affinity Purified
Target
Alternative Name GADD45GIP1 (GADD45GIP1 Antibody Abstract)
Background GADD45GIP1 acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. GADD45GIP1 acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. GADD45GIP1 may be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
Alias Symbols: CKBBP2, CRIF1, MGC4667, MGC4758, PLINP-1, PRG6, Plinp1
Protein Interaction Partner: FBXW11, UBC, LIN28A, EXOSC4, UPF2, TMEM177, MRPL11, MRPL14, TSR1, PTRH2, EIF3C, TAP1, MRPL12, APP, COPS5, HNRNPA1, NFE2L2, ICT1, AR, IKBKG, GADD45G, GADD45B, NR4A1, GADD45A, CSNK2B,
Protein Size: 222
Molecular Weight 24 kDa
Gene ID 90480
NCBI Accession NM_052850, NP_443082
UniProt Q8TAE8
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 222 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Images
Image no. 1 for anti-Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) (Middle Region) antibody (ABIN2789108) anti-Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) (Middle Region) antibody