Growth Differentiation Factor 5 (GDF5) ELISA Kits

The protein encoded by GDF5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. Additionally we are shipping GDF5 Antibodies (145) and GDF5 Proteins (44) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GDF5 8200 P43026
GDF5 14563 P43027
GDF5 252835  
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Top GDF5 ELISA Kits at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Mouse 6.2 pg/mL 15.6 pg/mL - 1000 pg/mL 96 Tests 13 to 16 Days
$757.89
Details
Human 6.7 pg/mL 15.6 pg/mL - 1000 pg/mL 96 Tests 13 to 16 Days
$589.47
Details
Rat 0.058 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$800.00
Details
Human 6.2 pg/mL 13.7 pg/mL - 10000 pg/mL   96 Tests 13 to 16 Days
$884.21
Details
Mouse 5.9 pg/mL 13.7 pg/mL - 10000 pg/mL   96 Tests 13 to 16 Days
$909.47
Details
Rat 6.5 pg/mL 13.7 pg/mL - 10000 pg/mL   96 Tests 13 to 16 Days
$960.00
Details
Rabbit 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Guinea Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Chicken 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests 12 to 14 Days
$715.00
Details

Top referenced GDF5 ELISA Kits

  1. Mouse (Murine) GDF5 ELISA Kit for Sandwich ELISA - ABIN425323 : Bae, Ohe, Lee, Heo, Byun, Bae, Kwon, Kwon: Photo-cured hyaluronic acid-based hydrogels containing growth and differentiation factor 5 (GDF-5) for bone tissue regeneration. in Bone 2013 (PubMed)
    Show all 2 Pubmed References

  2. Mouse (Murine) GDF5 ELISA Kit for Sandwich ELISA - ABIN815322 : Shtaif, Dror, Bar-Maisels, Phillip, Gat-Yablonski: Growth without growth hormone: can growth and differentiation factor 5 be the mediator? in Growth factors (Chur, Switzerland) 2015 (PubMed)

  3. Human GDF5 ELISA Kit for Sandwich ELISA - ABIN417836 : Bae, Kim, Lee, Heo, Yang, Kim, Kwon, Bang, Bae, Kwon: ZrO? surface chemically coated with hyaluronic acid hydrogel loading GDF-5 for osteogenesis in dentistry. in Carbohydrate polymers 2012 (PubMed)

More ELISA Kits for GDF5 Interaction Partners

Xenopus laevis Growth Differentiation Factor 5 (GDF5) interaction partners

  1. Changes in the expression of downstream regulators of skeletal differentiation, like barx1 and gdf5, is one mechanism by which head skeletal element number and articulation are altered during evolution.

  2. Results suggest that CDMP1/GDF5 requires cleavage by two distinct proteolytic enzymes.

Human Growth Differentiation Factor 5 (GDF5) interaction partners

  1. GDF5 rs143383 polymorphism was significantly associated with susceptibility to intervertebral disc degeneration and osteoarthritis. (Meta-analysis)

  2. Circular RNA CDR1anti-sense regulates osteoblastic differentiation of periodontal ligament stem cells via the miR-7/GDF5/SMAD and p38 MAPK signaling pathway.

  3. We found a strong association between the TT genotype and the risk of developing Knee Osteoarthritis (OR = 1.7, 95% CI = 1.12-2.8, p = 0.014), but not in the heterozygous TC state (OR = 1.56, CI 95% = 0.58-4.17, p = 0.367).

  4. study shows that there exists a relationship between GDF5 (SNP rs143383) and Developmental dysplasia of the hip (DDH) in our population. Second, we found for the first time that the genotype TT and the T allele were overly expressed in the patients and the fathers. More studies on the confirmation of this genetic marker for DDH are called for.

  5. Two Pakistani families with sequence variants in GDF5 and TRPS1 causing brachydactyly type C and tricho-rhino-phalangeal syndrome type III are described.

  6. The dysfunctional gene GDF5 was successfully corrected in adipose tissue-derived mesenchymal stem cells using a pair of transcription activatorlike effector nucleases.

  7. No association has been found between GDF5 +104 T/C promoter polymorphism and osteoarthritis in the Eastern Turkey population.

  8. The results of the current study revealed that SNP rs143383 of GDF5 is a compelling risk factor for knee OA [Osteoarthritis] and that GDF5 has an etiological effect on the development of OA [Osteoarthritis].

  9. A Study of IL-1beta, MMP-3, TGF-beta1, and GDF5 Polymorphisms and Their Association with Primary Frozen Shoulder in a Chinese Han Population

  10. BMP-14 rs143383 polymorphism reduced the susceptibility to knee osteoarthritis (OA) and hand OA not only in total analysis but also in subgroup analysis; BMP-14 rs143383 polymorphism may be a protective factor against OA occurrence

  11. The structure of Grem2-GDF5 complex has revealed a number of key findings for DAN-family mediated BMP2 inhibition.

  12. miR-615-3p negatively regulates the osteogenic differentiation of hLF cells through post-transcriptionally suppressing osteogenic regulators GDF5 and FOXO1.

  13. p38, c-jun, and NFkappaB pathways activated during intervertebral disc degeneration by IL-1beta but not GDF-5

  14. GDF5 elicited significant (p < 0.05) changes in the expression of anabolic, catabolic and hypertrophic genes with several consistent effects in healthy donors and in OA patients

  15. GDF5 was up regulated in patients after chronic rhinosinusitis developing osteitis.

  16. Titanium (Ti) surface modification with the combination of hBMP-2 and hGDF-5 for the two growth factor-coated Ti implants can improve the clinical properties of implants for orthopedic and dental applications.

  17. he large array of modular enhancers for Gdf5 provide a new foundation for studying the spatial specificity of joint patterning in vertebrates, as well as new candidates for regulatory regions that may also influence osteoarthritis risk in human population

  18. The purpose of this study is to investigate the immunohistochemical expression of cytokeratin 18 (CK18) and the reactivity to GDF5 (CDMP-1), called the morphogenetic protein-1, cartilage-derived, in lingual squamous cell carcinoma.

  19. homozygous sequence variants in the GDF5 gene underlie acromesomelic dysplasia type-grebe in consanguineous families

  20. The prevention of IL-1Beta-induced nucleus pulposus extracellular matrix degeneration by miR-7 silencing was attenuated by GDF5 siRNA.

Mouse (Murine) Growth Differentiation Factor 5 (GDF5) interaction partners

  1. Expression patterns of the joint marker Gdf5, tendon and ligament marker Scleraxis, early muscle marker MyoD1, and blood vessel marker Cadherin5 (Cdh5) are presented during the most active phases of embryonic mouse limb patterning.

  2. Hip morphology is profoundly affected by Gdf5 absence, and downstream regulatory sequences mediate its effects by controlling Gdf5 expression during development.

  3. Knee morphology is profoundly affected by Gdf5 absence, and downstream regulatory sequences mediate its effects by controlling Gdf5 expression in knee tissues

  4. Microarray analysis of satellite cells showed that expression of growth differentiation factor 5 (Gdf5) mRNA was markedly increased in Dnmt3a-KO mice. The DNA methylation level of the Gdf5 promoter was markedly decreased in Dnmt3a-KO satellite cells.

  5. Study concludes that growth/differentiation factor-5 (GDF-5) protects hippocampal neurons against kainic acid-induced neurodegeneration by signaling through bone morphogenetic protein receptor type IB, suggesting a therapeutic potential for GDF-5 in neurodegenerative diseases.

  6. spatiotemporal dynamics of Gdf5 expression may instruct lineage divergence.

  7. he large array of modular enhancers for Gdf5 provide a new foundation for studying the spatial specificity of joint patterning in vertebrates, as well as new candidates for regulatory regions that may also influence osteoarthritis risk in human population

  8. Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1-Smad5-Smad8 phosphorylation.

  9. Combined, these data suggest a possible pathway linking GDF5, ERG and downstream factors in the processes of chondrocyte differentiation during articular joint formation.

  10. Growth differentiation factor 5 is a novel target-derived factor that promotes sympathetic axon growth and branching and makes a distinctive regional contribution to the establishment of sympathetic innervation.

  11. Dach2 and Hdac9 mediate the effects of muscle activity on muscle reinnervation; Myog and Gdf5 appear to stimulate muscle reinnervation through parallel pathways

  12. Gdf-5 induced the expression of the alpha5 sub-unit, while Bmp-7 induced the expression of the alphaV sub-unit.

  13. Clonal expansion of Gdf5 progenitors contributes to linear growth of the enthesis.

  14. GDF5 might play a critical role in 3T3-L1 preadipocyte differentiation

  15. These results suggest that PI3K/Akt signals play a role in the GDF5-mediated brown adipogenesis through a mechanism related to activation of the Smad pathway.

  16. These results suggest that brown adipogenesis and energy homeostasis are both positively regulated by the GDF5/BMPR/Smad/PGC-1alpha signaling pathway in adipose tissues.

  17. apical and basal dendritic arbours of pyramidal cells throughout the hippocampus were stunted in both homozygous and heterozygous Gdf5 null mutants, indicating that dendrite size and complexity are sensitive to the level of endogenous GDF5 synthesis.

  18. This work implicates SOX11 as a potential regulator of GDF5 expression in joint maintenance and suggests a possible role in the pathogenesis of osteoarthritis

  19. A novel molecular mechanism of a GDF5 mutation affecting chondrogenesis and osteogenesis, is reported.

  20. Data show that revealed notochord cells in Gdf-5-null mice correctly form nuclei pulposi.

Cow (Bovine) Growth Differentiation Factor 5 (GDF5) interaction partners

  1. These results suggest that the SNP of the GDF5 gene could be a very useful genetic marker for body measurement traits in the bovine reproduction and breeding.

GDF5 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type\; brachydactyly, type C\; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.

Gene names and symbols associated with GDF5

  • growth differentiation factor 5 L homeolog (gdf5.L) antibody
  • growth differentiation factor 5 (GDF5) antibody
  • growth differentiation factor 5 (Gdf5) antibody
  • BDA1C antibody
  • BMP14 antibody
  • bp antibody
  • brp antibody
  • Cdmp-1 antibody
  • Cdmp1 antibody
  • gdf antibody
  • gdf-5 antibody
  • GDF5 antibody
  • LAP4 antibody
  • OS5 antibody
  • SYM1B antibody
  • SYNS2 antibody

Protein level used designations for GDF5

growth factor GDF5 , growth differentiation factor 5 , growth/differentiation factor 5-like , CDMP-1 , GDF-5 , cartilage-derived morphogenetic protein-1 , growth/differentiation factor 5 , radotermin , brachypodism , cartilage-derived morphogenetic protein 1 , growth differentiation factor 5 preproprotein , growth differentiation factor 5 (cartilage-derived morphogenetic protein-1)

GENE ID SPECIES
446295 Xenopus laevis
100137480 Papio anubis
100393400 Callithrix jacchus
8200 Homo sapiens
14563 Mus musculus
252835 Rattus norvegicus
100328897 Oryctolagus cuniculus
100723808 Cavia porcellus
100520988 Sus scrofa
485850 Canis lupus familiaris
539559 Bos taurus
374249 Gallus gallus
101116499 Ovis aries
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