GDF5 Products
(Growth Differentiation Factor 5 (GDF5))
Categories
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type\; brachydactyly, type C\; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development. [provided by RefSeq, Jul 2008].
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Featured GDF5 Categories
GDF5 Antibodies
High quality antibodies with extensive validation data.
GDF5 ELISA Kits
Reliable ELISA kits for a wide range of species.
GDF5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GDF5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7437095
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF
Validations
- (5)
Cat. No.
ABIN7154549
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7434680
Quantity
100 μL
Datasheet
Datasheet
Recommended GDF5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956329
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6956330
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN7035626
Quantity
96 tests
Datasheet
Datasheet
Recommended GDF5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123212
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123211
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN2565080
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our GDF5 products
: "In Vitro Osteogenic Differentiation Enhanced by Zirconia Coated with Nano-Layered Growth and Differentiation Factor-5." in: Journal of nanoscience and nanotechnology, Vol. 16, Issue 1, pp. 280-6, (2016) (PubMed).: "Growth without growth hormone: can growth and differentiation factor 5 be the mediator?" in: Growth factors (Chur, Switzerland), Vol. 33, Issue 4, pp. 309-18, (2015) (PubMed).
: "Dynamic profile and adipogenic role of growth differentiation factor 5 (GDF5) in the differentiation of 3T3-L1 preadipocytes." in: Archives of biochemistry and biophysics, Vol. 560, pp. 27-35, (2014) (PubMed).
: "Photo-cured hyaluronic acid-based hydrogels containing growth and differentiation factor 5 (GDF-5) for bone tissue regeneration." in: Bone, Vol. 59, pp. 189-98, (2013) (PubMed).
: "ZrO? surface chemically coated with hyaluronic acid hydrogel loading GDF-5 for osteogenesis in dentistry." in: Carbohydrate polymers, Vol. 92, Issue 1, pp. 167-75, (2012) (PubMed).
: "Identification of small molecular compounds and fabrication of its aqueous solution by laser-ablation, expanding primordial cartilage." in: Osteoarthritis and cartilage, Vol. 19, Issue 2, pp. 233-41, (2011) (PubMed).
: "GDF-5 is suppressed by IL-1beta and enhances TGF-beta3-mediated chondrogenic differentiation in human rheumatoid fibroblast-like synoviocytes." in: Experimental and molecular pathology, Vol. 88, Issue 1, pp. 163-70, (2010) (PubMed).
: "Combined use of bFGF and GDF-5 enhances the healing of medial collateral ligament injury." in: Biochemical and biophysical research communications, Vol. 402, Issue 2, pp. 329-34, (2010) (PubMed).
Synonyms and alternative names related to GDF5
growth differentiation factor 5 L homeolog (gdf5.L), growth differentiation factor 5 (GDF5), growth differentiation factor 5 (Gdf5), BDA1C, BMP14, bp, brp, Cdmp-1, CDMP1, Cdmp1, gdf, gdf-5, GDF5, LAP4, OS5, SYM1B, SYNS2Protein level used designations for GDF5
- growth factor GDF5
- growth differentiation factor 5
- growth/differentiation factor 5-like
- CDMP-1
- GDF-5
- cartilage-derived morphogenetic protein-1
- growth/differentiation factor 5
- radotermin
- brachypodism
- cartilage-derived morphogenetic protein 1
- growth differentiation factor 5 preproprotein
- growth differentiation factor 5 (cartilage-derived morphogenetic protein-1)
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