Growth Differentiation Factor 6 (GDF6) ELISA Kits

GDF6 encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. Additionally we are shipping Growth Differentiation Factor 6 Antibodies (67) and Growth Differentiation Factor 6 Proteins (15) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GDF6 392255 Q6KF10
GDF6 242316 P43028
GDF6 252834 Q6HA10
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Top Growth Differentiation Factor 6 ELISA Kits at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 0.059 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$736.84
Details
Mouse 3.91 pg/mL n/a   96 Tests 15 to 18 Days
$910.56
Details
Rat 5.86 pg/mL n/a   96 Tests 15 to 18 Days
$910.56
Details
Rabbit 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Guinea Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Chicken 9.375 ng/mL 15.625-1000 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Monkey 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Dog 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Sheep
  96 Tests 15 to 18 Days
$707.14
Details

More ELISA Kits for Growth Differentiation Factor 6 Interaction Partners

Human Growth Differentiation Factor 6 (GDF6) interaction partners

  1. GDF6 promotes vascular stabilization by restraining vascular endothelial growth factor signaling.

  2. findings indicate that increased BMP signaling owing to a GDF6 gain-of-function mutation is responsible for loss of joint formation and profound functional impairment in patients with Multiple Synostoses Syndrome 4.

  3. As fetal age increased, the expression of growth differentiation factor 6 was decreased correspondingly with the progress of ossification in vertebral bodies and restricted to cartilaginous regions.

  4. BMP13 has a role in enhancing extracellular matrix accumulation and inducing cell migration in certain intervertebral disc cells

  5. GDF6 is overexpressed in Leri's pleonosteosis.

  6. There was a possible weak association between the rs6982567 near GDF6 and polypoidal choroidal vasculopathy in this replication study with an independent Han Chinese cohort.

  7. Deficiency of gdf6 results in photoreceptor degeneration, so demonstrating a connection between Gdf6 signaling and photoreceptor survival.

  8. a critical role of HTRA1 in the regulation of angiogenesis via TGF-beta signaling and identified GDF6 as a novel disease gene for AMD.

  9. studies show that even though tenogenic (BMP 12 and BMP 13) and osteogenic (BMP2) BMPs bind the same receptors with high affinity they signal much differently and result in differential activation of osteogenic and tenogenic markers

  10. induces ligamentogenic differentiation in mesenchymal progenitors

  11. These data suggest a potential role for BMP-13 (the human homologue to GDF-6) in tendon matrix modeling and/or remodeling.

  12. The spectrum of disorders generated by morpholino inhibition and the more severe defects (microphthalmia and anophthalmia) observed at higher doses illustrate the key role of GDF6 in ocular development.

  13. Mutation screening of a large and clinically diverse Klippel-Feil syndrome (KFS) cohort has identified GDF6 missense mutations in both familial and sporadic KFS patients.

  14. These data establish the important role of growth differentiation factor 6 in ocular and vertebral development.

  15. BMP-13 inhibited osteogenic differentiation of bone marrow multipotent mesenchymal stromal cells, implying that functional mutations or deficiency of BMP-13 may allow excess bone formation

Mouse (Murine) Growth Differentiation Factor 6 (GDF6) interaction partners

  1. Upregulation of Gdf6 restored the osteogenic capacity of old mesenchymal stem cells in vitro and exerted positive effects in vivo on aging-associated pathologies such as reduced lymphopoiesis, insufficient muscle repair, reduced numbers of neural progenitors in the brain, and chronic inflammation.

  2. data indicate that BMP9 and BMP13 (BMP9 might be more effective) promoted the differentiation of C3H10T1/2 cells into cardiomyocyte-like cells

  3. Over-expression of Gdf6 induces commitment of pluripotent mesenchymal C3H10T1/2 cells to the adipocyte lineage.

  4. Gdf6 plays an inhibitory role to prevent the osteogenic differentiation of the coronal suture mesenchyme

  5. a critical role of HTRA1 in the regulation of angiogenesis via TGF-beta signaling and identified GDF6 as a novel disease gene for AMD.

  6. These data suggest a potential role for BMP-13 (the human homologue to GDF-6) in tendon matrix modeling and/or remodeling.

  7. role of single and double mutations in the mouse Gdf6 and Gdf5 genes in multiple joint and skeletal patterning defects

  8. The sequences for complex, regulatory elements responsible for Gdf6 regulation during embryonic skeletal development have been identified.

  9. These data establish the important role of growth differentiation factor 6 in ocular and vertebral development.

Zebrafish Growth Differentiation Factor 6 (GDF6) interaction partners

  1. GDF6 promotes vascular stabilization by restraining vascular endothelial growth factor signaling.

  2. The role of Gdf6a signaling in superior ocular sulcus morphogenesis.

  3. This work establishes a novel link between tbx2b and gdf6a in determining photoreceptor fates.

  4. gdf6a is a dorsal initiation signal acting from the extraocular non-neural ectoderm during optic vesicle evagination.

  5. Radar is regulated in the pharyngeal arches by a distant conserved element and has similar functions in skeletal development in fish and mammals.

  6. Maternal induction of bone morphogenetic proteins by Radar is essential for zebrafish development as its removal results in larval-lethal dorsalized phenotypes.

  7. Radar protein expression provides insights into dorsoventral patterning.

  8. The spectrum of disorders generated by morpholino inhibition and the more severe defects (microphthalmia and anophthalmia) observed at higher doses illustrate the key role of GDF6 in ocular development.

  9. These data establish the important role of growth differentiation factor 6 in ocular and vertebral development.

  10. Radar is near the top of a signaling cascade that establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map

  11. Gdf6a initiates dorsal retinal patterning independent of Bmp4, and regulates lens differentiation.

Xenopus laevis Growth Differentiation Factor 6 (GDF6) interaction partners

  1. GDF6 knockdown in Xenopus results in a high incidence of anterior axial defects consistent with a role for GDF6 in the etiology, diversity, and variability of Klippel-Feil syndrome.

Growth Differentiation Factor 6 (GDF6) Antigen Profile

Antigen Summary

This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. It is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), which is a congenital disorder of spinal segmentation.

Gene names and symbols associated with GDF6

  • growth differentiation factor 6 (GDF6) antibody
  • growth differentiation factor 6 (Gdf6) antibody
  • growth differentiation factor 6 (gdf6) antibody
  • growth differentiation factor 6a (gdf6a) antibody
  • growth differentiation factor 6 S homeolog (gdf6.S) antibody
  • bmp13 antibody
  • CDMP-2 antibody
  • cdmp2 antibody
  • gdf-6 antibody
  • gdf6 antibody
  • gdf16 antibody
  • KFM antibody
  • kfs antibody
  • KFS1 antibody
  • kfsl antibody
  • LCA17 antibody
  • MCOP4 antibody
  • MCOPCB6 antibody
  • rdr antibody
  • sb:cb278 antibody
  • SCDO4 antibody
  • sgm1 antibody

Protein level used designations for GDF6

GDF-6 , Klip-Feil malformation , Klippel-Feil malformation , Klippel-Feil syndrome , growth/differentiation factor 16 , growth/differentiation factor 6 , growth differentiation factor 16 , cartilage-derived morphogenetic protein 2 , growth differentiation factor 6 , GDF-6-A , cb278 , darl , growth/differentiation factor 6-A , out , protein radar , radar , growth and differentiation factor 6 , growth differentiation factor 6 S homeolog

GENE ID SPECIES
392255 Homo sapiens
242316 Mus musculus
252834 Rattus norvegicus
407175 Bos taurus
548831 Xenopus (Silurana) tropicalis
566470 Danio rerio
100686579 Canis lupus familiaris
100059475 Equus caballus
100731904 Cavia porcellus
100355026 Oryctolagus cuniculus
101108925 Ovis aries
701126 Macaca mulatta
399144 Xenopus laevis
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