Helicase-Like Transcription Factor (HLTF) ELISA Kits

HLTF encodes a member of the SWI/SNF family. Additionally we are shipping HLTF Antibodies (90) and HLTF Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HLTF 6596 Q14527
HLTF 20585 Q6PCN7
HLTF 295568  
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Top HLTF ELISA Kits at antibodies-online.com

Showing 8 out of 18 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 18.75 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests 12 to 14 Days
$630.00
Details
Mouse 18.75 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests 12 to 14 Days
$630.00
Details
Rat 37.5 pg/mL 62.5-4000 pg/mL Typical standard curve 96 Tests 12 to 14 Days
$638.00
Details
Monkey 18.75 pg/mL 31.25-2000 pg/mL   96 Tests 12 to 14 Days
$715.00
Details
Chicken 37.5 pg/mL 62.5-4000 pg/mL   96 Tests 12 to 14 Days
$715.00
Details
Rabbit 0.375 ng/mL 0.625-40 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Guinea Pig 75 pg/mL 125-8000 pg/mL   96 Tests 12 to 14 Days
$715.00
Details
Pig 18.75 pg/mL 31.25-2000 pg/mL   96 Tests 12 to 14 Days
$715.00
Details

More ELISA Kits for HLTF Interaction Partners

Human Helicase-Like Transcription Factor (HLTF) interaction partners

  1. ALDH1A1 overexpression was found to enhance Lysosomal autophagy inhibitors (LAI) cell entry and cytotoxicity without directly affecting lysosome function or autophagic flux. Expression of HLTF allows repair of DNA damage caused by LAI-induced reactive oxygen species, leading to hydroxychloroquine resistance.

  2. Regulation of HLTF-mediated PCNA polyubiquitination by RFC and PCNA monoubiquitination levels determines choice of damage tolerance pathway.

  3. Study suggest that HLTF functions as a tumor suppressor gene in colorectal cancer (CRC). HLTF downregulation promotes the migration and invasion of CRC cells in vitro. Furthermore, HLTF expression is negatively associated with overall survival in patients with CRC. HLTF may suppress the migration and invasion of CRC cells by targeting TGFbeta/SMAD signaling.

  4. Data suggest that HIV-1 vpr mediates polyubiquitination of HLTF by directly loading it onto C-terminal WD40 domain of DCAF1 in complex the CRL4, an E3 ubiquitin ligase. (vpr = vpr gene product of Human immunodeficiency virus 1; HLTF = human helicase like transcription factor; DCAF1 = human Vpr (HIV-1) binding protein; CRL4 = human E3 ubiquitin ligase CRL4)

  5. A low WT HLTF expression with a high I21R HLTF expression is associated with a poor disease-free survival

  6. the present study does not provide any strong evidence that PAI-1 gene variants are implicated in the risk of DR or the development of DR during T2DM course.

  7. A large number of SNF2 family, DNA and ATP-dependent motor proteins are needed during transcription, DNA replication, and DNA repair to manipulate protein-DNA interactions and change DNA structure. SMARCAL1, ZRANB3, and HLTF are three related members of this family with specialized functions that maintain genome stability during DNA replication. [review]

  8. depletion of SMARCAL1, a SNF2-family DNA translocase that remodels stalled forks, restores replication fork stability and reduces the formation of replication stress-induced DNA breaks and chromosomal aberrations in BRCA1/2-deficient cells. In addition to SMARCAL1, other SNF2-family fork remodelers, including ZRANB3 and HLTF, cause nascent DNA degradation and genomic instability

  9. HIV-1 vpr reprograms CRL4(DCAF1) E3 to direct HLTF for proteasome-dependent degradation independent from previously reported Vpr interactions with base excision repair enzyme uracil DNA glycosylase (UNG2) and crossover junction endonuclease MUS81, which Vpr also directs for degradation via CRL4(DCAF1) E3.

  10. Fasudil reduced LPS-mediated TF and PAI-1 expression and activity in PBMCs. These effects may partially be relevant to the clinical benefits of fasudil in the treatment of CAPD patients.

  11. HLTF is degraded in lymphocytic cells and macrophages infected with Vpr-expressing HIV-1. Our results reveal a previously unidentified strategy for HIV-1 to antagonize DNA repair in host cells.

  12. HLTF expression is altered in various cancers via two mechanisms: gene silencing through promoter hypermethylation or alternative mRNA splicing, which leads to the expression of truncated proteins that lack DNA repair domains. [review]

  13. HLTF promotes the filling-in of gaps left opposite damaged DNA during replication, and this postreplication repair function depends on its HIRAN domain.

  14. Findings indicate a mechanism of helicase-like transcription factor HLTF-mediated fork reversal and suggest the requirement for distinct fork remodeling activities in the cell.

  15. These results suggest that the HIRAN domain functions as a sensor to the 3'-end of the primer strand at the stalled replication fork and that the domain facilitates fork regression.

  16. Study demonstrates a correlation between HLTF expression level and thyroid neoplastic progression where three truncated forms are detected in thyroid carcinoma.

  17. We were able to provide evidence that methylation of HLTF and especially HPP1 detected in serum is strongly correlated with cell death in CRC using LDH as surrogate marker

  18. Results demonstrate that loss of HLTF function promotes the malignant transformation of intestinal or colonic adenomas to carcinomas by inducing genomic instability.

  19. results delineate a previously unknown USP7-HLTF-PCNA molecular network controlling DNA damage response

  20. HLTF can displace a broad spectrum of proteins such as replication protein A (RPA), PCNA, and replication factor C (RFC), thereby providing the first example for a protein clearing activity at the stalled replication fork.

Rabbit Helicase-Like Transcription Factor (HLTF) interaction partners

  1. Prolactin dependent Jak2 phosphorylation of RUSH.

  2. Splice arrays and RT-PCR showed that although most splice variants in RUSH and ATP11B are conserved in human and rabbit, the RFBP isoform is specific to rabbit.

Mouse (Murine) Helicase-Like Transcription Factor (HLTF) interaction partners

  1. Findings 1) prove the truncated Hltf protein isoform is a transcription factor, 2) establish a functional link between AS of Hltf and immunosuppression at the feto-maternal interface, 3) correlate intron retention with the absence of DNA methylation, and 4) underscore the importance of differential splicing analysis to identify Hltf's functional diversity.

  2. silencing Hltf during heart organogenesis compromised DNA double-strand break repair, and caused aberrant collagen biogenesis altering the structural network that transmits cardiomyocyte force into muscle contraction

  3. Data show a role of helicase-like transcription factor (hltf) in the G2/m transition and apoptosis in brain

  4. p11 and AnxA2 cooperate to create a unique binding pocket, but the optimal binding condition is not achieved without conformational changes associated with target binding. Upon interaction with the SMARCA3 peptide, both Asp60 in p11 and Ser12 in AnxA2 flip inward toward the peptide-binding groove, forming additional intermolecular hydrogen bonds.

  5. Results demonstrate that loss of HLTF function promotes the malignant transformation of intestinal or colonic adenomas to carcinomas by inducing genomic instability.

HLTF Antigen Profile

Antigen Summary

This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein.

Gene names and symbols associated with HLTF

  • helicase like transcription factor (HLTF) antibody
  • helicase-like transcription factor (hltf) antibody
  • helicase-like transcription factor L homeolog (hltf.L) antibody
  • helicase like transcription factor (hltf) antibody
  • helicase-like transcription factor (Hltf) antibody
  • helicase like transcription factor (Hltf) antibody
  • AF010600 antibody
  • BC057116 antibody
  • HIP116 antibody
  • HIP116A antibody
  • HLTF antibody
  • HLTF1 antibody
  • MGC131155 antibody
  • P113 antibody
  • RNF80 antibody
  • RUSH antibody
  • Smarca3 antibody
  • Snf2l3 antibody
  • wu:fc33f07 antibody
  • ZBU1 antibody

Protein level used designations for HLTF

helicase-like transcription factor , SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a3 , DNA-binding protein/plasminogen activator inhibitor 1 regulator , DNA-binding protein/plasminogen activator inhibitor-1 regulator , RING finger protein 80 , SNF2-like 3 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 , sucrose nonfermenting protein 2-like 3 , sucrose nonfermenting-like 3 , RUSH 1 , RUSH-1 , TNF-response element-binding protein , helicase-like transcription factor-like protein

GENE ID SPECIES
100058775 Equus caballus
324585 Danio rerio
460766 Pan troglodytes
735224 Xenopus laevis
100404714 Callithrix jacchus
100431605 Pongo abelii
100471960 Ailuropoda melanoleuca
100555259 Anolis carolinensis
100580659 Nomascus leucogenys
100617443 Monodelphis domestica
6596 Homo sapiens
100009232 Oryctolagus cuniculus
20585 Mus musculus
295568 Rattus norvegicus
477106 Canis lupus familiaris
539633 Bos taurus
100520979 Sus scrofa
100716292 Cavia porcellus
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