Hematological and Neurological Expressed 1 (HN1) ELISA Kits

HN1 encodes a member of the Notch family. Additionally we are shipping HN1 Antibodies (67) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HN1 51155 Q9UK76
HN1 287828 Q6AXU6
HN1 15374 P97825
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Top HN1 ELISA Kits at antibodies-online.com

Showing 4 out of 9 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 15.6 pg/mL 62.5-4000 pg/mL Typical standard curve 96 Tests 15 to 18 Days
$910.56
Details
Mouse
  96 Tests 21 to 31 Days
$796.95
Details
Rat < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
$838.60
Details
Cow
  96 Tests 15 to 18 Days
$1,029.60
Details

More ELISA Kits for HN1 Interaction Partners

Human Hematological and Neurological Expressed 1 (HN1) interaction partners

  1. Downregulation of MYC abrogated the effect of HN1 overexpression in breast cancer cell lines. Taken together, these data reveal that HN1 promotes the progression of breast cancer by upregulating MYC expression, and might be a therapeutic target for breast cancer.

  2. Data report that HN1 is an essential factor for beta-catenin turnover and signaling, augments cell growth and migration in prostate cancer cells.

  3. miR-132 is significantly down-regulated in breast cancer tissues and cancer cell lines. Additional study identifies HN1 as a novel direct target of miR-132. MiR-132 down-regulates HN1 expression by binding to the 3' UTR of HN1.

  4. HN1 maintains a balance between the androgen-regulated nuclear translocation of androgen receptor and steady-state Akt phosphorylation, predominantly in the absence of androgens.

  5. EGF and kinase inhibitors increase HN1 expression, and Silencing of HN1 results in cell cycle alterations in prostate cells.

  6. These data suggest a role for Hn1 in the biology of malignant brain tumors.

Mouse (Murine) Hematological and Neurological Expressed 1 (HN1) interaction partners

  1. These data suggest a role for Hn1 in the biology of malignant brain tumors.

  2. Hn1 mRNA was upregulated in injured facial motoneurons in both rats and mice.These findings identify Hn1 as a gene associated with nervous system development and nerve regeneration.

  3. Hn1 depletion in B16.F10 melanoma cells promotes a differentiated phenotype that includes increased melanogenesis and cell cycle arrest.

HN1 Antigen Profile

Antigen Summary

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.

Gene names and symbols associated with HN1

  • Jupiter microtubule associated homolog 1 (JPT1) antibody
  • Jupiter microtubule associated homolog 1 (Jpt1) antibody
  • Jupiter microtubule associated homolog 1a (jpt1a) antibody
  • hematological and neurological expressed 1 (hn1) antibody
  • Jupiter microtubule associated homolog 1 (jpt1) antibody
  • arm2 antibody
  • Hn1 antibody
  • hn1a antibody
  • zgc:163138 antibody

Protein level used designations for HN1

androgen-regulated protein 2 , hematological and neurological expressed 1 protein , hematological and neurological expressed sequence 1 , hematological and neurological expressed 1

GENE ID SPECIES
51155 Homo sapiens
287828 Rattus norvegicus
422119 Gallus gallus
450249 Pan troglodytes
613381 Bos taurus
100037360 Danio rerio
100137056 Salmo salar
100271760 Xenopus (Silurana) tropicalis
15374 Mus musculus
100719480 Cavia porcellus
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