Hematopoietic Prostaglandin D Synthase (HPGDS) ELISA Kits

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. Additionally we are shipping HPGDS Antibodies (26) and HPGDS Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HPGDS 27306 O60760
HPGDS 54486 Q9JHF7
HPGDS 58962 O35543
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Top HPGDS ELISA Kits at antibodies-online.com

Showing 4 out of 19 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Mouse 0.065 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
Human 0.09 ng/mL 0.312-20 ng/mL   96 Tests 2 to 3 Days
  96 Tests 11 to 18 Days
  96 Tests 15 to 18 Days

More ELISA Kits for HPGDS Interaction Partners

Human Hematopoietic Prostaglandin D Synthase (HPGDS) interaction partners

  1. The expression levels of CDC20 and PTGDS were able to predict overall survival in diffuse large B-cell lymphoma patients.

  2. Prostaglandin D2 synthase 21 kDa (brain) (PTGDS) was found to be expressed at a significantly higher level in the tumors of highgrade serous ovarian cancer (HGSOC) patients with a short diseasefree survival time. Inverse profile, with positivity for PTGDS product prostaglandin D2 strongly associated with an increase in diseasefree survival, the absence of relapse and sensitivity to platinumbased therapy.

  3. The DHEA metabolite 7beta-hydroxy-epiandrosterone exerts anti-estrogenic effects on breast cancer cell lines.

  4. Lipocalin-type PGD synthase is a novel phytocannabinoid-binding protein.

  5. High lipocalin-type prostaglandin D synthase expression is associated with Spontaneous intracranial hypotension.

  6. Measurement of serum BTP can be a reliable tool for detecting kidney function in neonates.

  7. Thus, our results suggest decreased NK cell-mediated eosinophil regulation, possibly through an increased level of PGD2, as a previously unrecognized link between PG dysregulation and eosinophilic inflammation in CRS.

  8. These observations suggest that tumor cell-derived inflammatory cytokines increase L-PGDS expression and subsequent PGD2 production in the tumor endothelial cells (ECs). This PGD2 acts as a negative regulator of the tumorigenic changes in tumor ECs.

  9. we have utilized a broad-scaled affinity proteomics approach to identify three proteins (CCL5, HPGDS, and NPSR1) with altered plasma levels in asthmatic children compared to healthy controls, representing the first evaluation of HPGDS and NPSR1 in plasma.

  10. the development of a competition binding assay amenable to high-throughput screening (HTS) in a scintillation proximity assay (SPA) format. This assay was used to screen an in-house compound library of approximately 280,000 compounds for novel H-PGDS inhibitors.

  11. The cut off value for betaTP in the diagnosis and follow-up of cerebrospinal fluid leaks should be modified depending on the type of secretion (sample type), for a better diagnostic accuracy

  12. Serum levels of beta trace protein and beta 2 microglobulin can be used to predict residual kidney function in hemodialysis patients.

  13. BTP and B2M levels are less affected than serum by amputation, and should be considered for future study of GFR estimation

  14. Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function

  15. levels of L-PGDS in cervicovaginal secretions of pregnant women at different stages of parturition correlate with preterm birth.

  16. Given that uPGDS levels fall after treatment of LN, uPGDS may be used to monitor the efficacy of therapy. It can also differentiate patients with active nephritis and active non renal lupus.

  17. PTGDS mRNA expression was down-regulated in rapid-cycling bipolar disorder patients in a euthymic, depressive, and manic/hypomanic state compared with healthy control subjects.

  18. Expression of MR and prostaglandin D2 synthase is strongly correlated in adipose tissues from obese patients.

  19. involved in pathogenesis of androgenetic alopecia [review]

  20. These data indicate that scalp is spatially programmed via mast cell prostaglandin D-synthase distribution in a manner reminiscent of the pattern seen in androgenetic alopecia.

Mouse (Murine) Hematopoietic Prostaglandin D Synthase (HPGDS) interaction partners

  1. Validation of differentially expressed genes (DEGs) by quantitative RT-PCR showed a significant increase in PLA2 group 4c (Pla2g4c)/COX-2 (Ptgs2)/PGD2 synthase 2 (Hpgds) axis. PGD2 level in bronchoalveolar fluids of the OA-challenged mice was significantly increased. A 24-h incubation of BSM tissues with PGD2 caused a hyperresponsiveness to acetylcholine in naive control mice.

  2. H-PGDS deficiency accelerates the production of SDF-1alpha and the activity of MMP-9 in the antigen-stimulated intestine. SDF-1alpha receptor blockade or MMP-9 inhibition relieves the exacerbated mast cell hyperplasia and manifestations observed in H-PGDS(-/-).

  3. HPGDS may play a role in the regulation of inflammation and epithelial cell health within the oviduct.

  4. Data suggest a role for hematopoietic prostaglandin D synthase-produced prostaglandin D(2) in the initial nuclear translocation of SOX9.

  5. These data suggest that PGD(2) generated via HPGDS has detrimental effects after spinal cord injury and that blocking the activity of this enzyme can be beneficial.

  6. hPGD(2)S-derived cyclopentenone prostaglandins may protect against inflammatory diseases, where T lymphocytes play a pathogenic role, as in rheumatoid arthritis, atopic eczema, and chronic rejection

  7. Our results demonstrated that the neuroprotective effects of HPGDS in our model are mediated by suppression of activation and infiltration of inflammatory cells.

HPGDS Antigen Profile

Antigen Summary

The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.

Gene names and symbols associated with HPGDS

  • hematopoietic prostaglandin D synthase (HPGDS) antibody
  • prostaglandin D2 synthase (PTGDS) antibody
  • hematopoietic prostaglandin D synthase (hpgds) antibody
  • hematopoietic prostaglandin D synthase (Hpgds) antibody
  • hematopoietic prostaglandin D synthase L homeolog (hpgds.L) antibody
  • gsts antibody
  • GSTS1-1 antibody
  • H-PGDS antibody
  • hpgds antibody
  • hpgds-a antibody
  • hpgds-b antibody
  • hpgdsa antibody
  • L-PGDS antibody
  • LPGDS antibody
  • PDS antibody
  • PGD2 antibody
  • pgds antibody
  • PGDS2 antibody
  • Ptgds2 antibody
  • XlGSTS1 antibody

Protein level used designations for HPGDS

GST class-sigma , glutathione S-transferase sigma , glutathione-dependent PGD synthase , glutathione-dependent PGD synthetase , glutathione-requiring prostaglandin D synthase , hematopoietic prostaglandin D2 synthase , prostaglandin-H2 D-isomerase , PGD2 synthase , beta-trace protein , cerebrin-28 , glutathione-independent PGD synthase , glutathione-independent PGD synthetase , lipocalin-type prostaglandin D synthase , lipocalin-type prostaglandin-D synthase , prostaglandin D synthase , prostaglandin-D2 synthase , prostaglandin D2 synthase, hematopoietic , glutathione S-transferase , prostaglandin D2 synthase 2, hematopoietic , H-PGDS , prostaglandin-D synthase , hematopoietic prostaglandin D synthase , hematopoietic prostaglandin D synthase a , prostaglandin D2 synthase, hematopoietic a

27306 Homo sapiens
5730 Homo sapiens
448666 Xenopus (Silurana) tropicalis
54486 Mus musculus
58962 Rattus norvegicus
395863 Gallus gallus
100139892 Bos taurus
398969 Xenopus laevis
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