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anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) Antibodies

HNRNPC belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Additionally we are shipping Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) Kits (15) and Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HNRNPC 3183 P07910
HNRNPC 15381 Q9Z204
HNRNPC 290046  
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Top anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) Antibodies at antibodies-online.com

Showing 10 out of 141 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-HNRPC Antibody Titration: 0.2-1 ug/ml Positive Control: Jurkat cell lysate HNRNPC is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-HNRNPC Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T Sample type: human aveolar basal endothelial cells (25ug)Primary Dilution: 1:1000Secondary Antibody: Goat anti-Rabbit-HRPSecondary Dilution: 1:5000Image Submitted by: Andreas Eisenreich Charite Universitatsmedizin Berlin 100 μL 2 to 3 Days
$289.00
Details
Chicken Mouse Un-conjugated ICC, IF, IHC (p), IP, ELISA, WB Western blot of hnRNP-C1/C2 on Hela extracts 50 μL 7 to 8 Days
$447.65
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: Hnrnpc Antibody Dilution: 1.0ug/ml Sample Type: Mouse Lung 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of hNRNP C staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of hNRNP C expression in MCF7 (A), K562 (B), HeLa (C) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of hNRNP C staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated wi Western blot analysis of hNRNP C expression in HEK293T (A), HuvEc (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of hNRNP C (pS260) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then in Western blot analysis of hNRNP C (pS260) expression in Hela (A), K562 (B), HEK293T (C) whole cell lysates. 200 μL 13 to 14 Days
$575.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB ABIN6268809 at 1/100 staining human brain tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of hnRNP C1/C2 Antibody expression in 293 cells lysates.The lane on the left is treated with the antigen-specific peptide. 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from HepG2/COLO205 cells, using hnRNP C1/C2 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using hnRNP C1/C2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB HNRNPC antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human bladder carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the HNRNPC antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. HNRNPC Antibody (C-term) western blot analysis in Jurkat,K562,U251 cell line lysates (35ug/lane).This demonstrates the HNRNPC antibody detected the HNRNPC protein (arrow). 400 μL 10 to 11 Days
$385.00
Details

Top referenced anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) Antibodies

  1. Chicken Monoclonal HNRNPC Primary Antibody for ICC, IF - ABIN108591 : Dreyfuss, Choi, Adam: Characterization of heterogeneous nuclear RNA-protein complexes in vivo with monoclonal antibodies. in Molecular and cellular biology 1984 (PubMed)
    Show all 12 Pubmed References

  2. Chicken Monoclonal HNRNPC Primary Antibody for ICC, IF - ABIN108590 : Choi, Dreyfuss: Isolation of the heterogeneous nuclear RNA-ribonucleoprotein complex (hnRNP): a unique supramolecular assembly. in Proceedings of the National Academy of Sciences of the United States of America 1985 (PubMed)
    Show all 12 Pubmed References

  3. Monoclonal HNRNPC Primary Antibody for IF, IP - ABIN534206 : Zhang, Tai, Wong, Tai, Koay, Chen: Molecular response of leukemia HL-60 cells to genistein treatment, a proteomics study. in Leukemia research 2006 (PubMed)
    Show all 3 Pubmed References

  4. Dog (Canine) Polyclonal HNRNPC Primary Antibody for WB - ABIN2776586 : Rual, Venkatesan, Hao, Hirozane-Kishikawa, Dricot, Li, Berriz, Gibbons, Dreze, Ayivi-Guedehoussou, Klitgord, Simon, Boxem, Milstein, Rosenberg, Goldberg, Zhang, Wong, Franklin, Li, Albala, Lim et al.: Towards a proteome-scale map of the human protein-protein interaction network. ... in Nature 2005 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) Interaction Partners

Human Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) interaction partners

  1. APP levels then decrease progressively as a function of age in close relationship with the gradual normalization of FMRP and hnRNP C levels.

  2. Endoplasmic reticulum resident chaperone GRP78, mitochondrial protein Prohibitin and heterogeneous nuclear ribonucleoprotein hnRNPC (C1/C2) have been shown to interact with viral RNA. Hence it is proposed that these are the principle candidates governing endoplasmic reticulum stress-induced apoptosis in JEV infection.

  3. Our results indicate that a balance between lncRNA SNHG1 and hnRNPC regulates p53 activity and p53-dependent apoptosis upon doxorubicin treatment, and further indicate that a change in lncRNA subcellular localization under specific circumstances is biologically significant.

  4. These data suggest an interplay between CELF2 and hnRNP C as the mechanistic basis for activation-dependent alternative splicing of TRAF3 exon 8.

  5. These data indicate that hnRNPC1/C2 binds to both DNA and RNA and influences both gene expression and RNA splicing, but these actions do not appear to be linked through 1,25(OH)2D-mediated induction of transcription.

  6. These findings suggest that hnRNP C1/C2 is involved in dengue virus replication at the stage of viral RNA synthesis.

  7. HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform.

  8. Our results suggested that hnRNP C1 controls HPV16 late gene expression.

  9. m(6)A-switch-regulated HNRNPC-binding activities affect the abundance as well as alternative splicing of target mRNAs, demonstrating the regulatory role of m(6)A-switches on gene expression and RNA maturation

  10. PTBP1 and hnRNP C repress exon 3 inclusion, and that downregulation of PTBP1 inhibited BIM-mediated apoptosis.

  11. down-regulation of MALAT-1 expression compromised the cytoplasmic translocation of hnRNP C in the G2/M phase and resulted in G2/M arrest

  12. Heterogeneous nuclear ribonucleoprotein C is a key regulator of BRCA gene expression and homologous recombination-based DNA repair.

  13. By preventing U2AF65 binding to Alu elements, hnRNP C plays a critical role as a genome-wide sentinel protecting the transcriptome.

  14. The data indicated that hnRNPC controls the aggressiveness of glioblastoma cells through the regulation of PDCD4. Silencing of hnRNPC lowered miR-21 levels, in turn increasing the expression of PDCD4, suppressing Akt and p70S6K activation.

  15. p27kip1 upregulated by hnRNPC1/2 antagonizes CagA-mediated pathogenesis.

  16. study shows mechanism by which Pol II transcripts are classified according to length; heterotetramer of hnRNP C1/C2 measures the length of the transcripts like a molecular ruler, by binding to unstructured RNA regions longer than 200 to 300 nucleotides

  17. One of the identified proteins, hnRNPC, was found to interact with small hepatitis delta virus antigen in vitro and in vivo in human liver cells.

  18. Studies indicated that DDX21, HNRNPC, and RCC2 were isolated from Ku86 multicomponent complex in response to DNA damage.

  19. HNRNP C recognizes uridine tracts with a defined long-range spacing consistent with HNRNP particle organization.

  20. FMRP represses translation by recruiting APP mRNA to processing bodies, whereas hnRNP C promotes APP translation by displacing FMRP, thereby relieving the translational block.

Mouse (Murine) Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) interaction partners

  1. The data show that hnRNPC1 may be involved in the internalization of miR-30d inside exosomes.

  2. APP levels then decrease progressively as a function of age in close relationship with the gradual normalization of FMRP and hnRNP C levels.

  3. hnRNP C and hnRNP H bind to the 3'-UTR of the circadian clock gene Period 2 (mPer2).

  4. Neither hnRNP-C nor FMRP is required for cyclic AMP to stimulate APP and Amyloid beta production.

  5. our results reveal a new function of the splicing factor hnRNP C in the maturation of dendritic cells that involves regulating the expression of NF-kappaB p65 and its downstream targets CD80 and CD40.

  6. CK1alpha-mediated phosphorylation modulates the mRNA binding ability of hnRNP-C

  7. Data suggest that increased levels of hnRNP C1/C2 may modulate XIAP translation by interacting with the XIAP-IRES, and may foster synthesis of XIAP as a protective pathway by which neurons try to counteract the initial deleterious effects of apoptosis.

Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) Antigen Profile

Protein Summary

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.

Gene names and symbols associated with HNRNPC

  • heterogeneous nuclear ribonucleoprotein C (C1/C2) (HNRNPC) antibody
  • heterogeneous nuclear ribonucleoprotein C (C1/C2) S homeolog (hnrnpc.S) antibody
  • heterogeneous nuclear ribonucleoprotein C (hnrnpc) antibody
  • heterogeneous nuclear ribonucleoprotein C (Hnrnpc) antibody
  • heterogeneous nuclear ribonucleoprotein C (C1/C2) L homeolog (hnrnpc.L) antibody
  • heterogeneous nuclear ribonucleoprotein C (C1/C2) (Hnrnpc) antibody
  • AL022939 antibody
  • bZ1G18.4 antibody
  • C1 antibody
  • C2 antibody
  • D14Wsu171e antibody
  • fb57h12 antibody
  • fi16b11 antibody
  • hnrnp antibody
  • hnrnp-C antibody
  • hnRNP C antibody
  • HNRNPC antibody
  • hnRNPC1 antibody
  • hnRNPC2 antibody
  • hnrpc antibody
  • Hnrpc1 antibody
  • Hnrpc2 antibody
  • MGC53243 antibody
  • snrpc antibody
  • wu:fb57h12 antibody
  • wu:fi16b11 antibody
  • zgc:55701 antibody

Protein level used designations for HNRNPC

heterogeneous nuclear ribonucleoproteins C1/C2 , hnRNP C1/C2 , nuclear ribonucleoprotein particle C1 protein , nuclear ribonucleoprotein particle C2 protein , heterogeneous nuclear ribonucleoprotein C (C1/C2) , heterogeneous nuclear ribonucleoprotein C1 , heterogeneous nuclear ribonucleoprotein C2 , heterogeneous ribonucleoprotein C1/C2 , hnRNP C1 / hnRNP C2 , hnRNP C2 , snoRNA MBI-122 , heterogeneous nuclear ribonucleoprotein C , hnRNP C protein C-terminal fragment (158 AA) , hnRNP core protein C , hnRNP C , C protein

GENE ID SPECIES
3183 Homo sapiens
379948 Xenopus laevis
465214 Pan troglodytes
475399 Canis lupus familiaris
510852 Bos taurus
406352 Danio rerio
15381 Mus musculus
290046 Rattus norvegicus
100008686 Oryctolagus cuniculus
100860966 Capra hircus
397793 Xenopus laevis
100713856 Cavia porcellus
100059269 Equus caballus
100626496 Sus scrofa
101925475 Macaca fascicularis
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