anti-Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) Antibodies

HNRNPH1 encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Additionally we are shipping HNRNPH1 Kits (14) and HNRNPH1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HNRNPH1 3187 P31943
HNRNPH1 59013 O35737
HNRNPH1 140931 Q8VHV7
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Top anti-HNRNPH1 Antibodies at antibodies-online.com

Showing 10 out of 113 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated IF, IP, IHC, WB IHC Information: Paraffin embedded testis tissue, tested with an antibody dilution of 5 ug/ml. 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of HnRNP H expression in HELA whole cell lysates ( Lane 1) and HEPG2 whole cell lysates ( Lane 2). HnRNP H at 49KD was detected using rabbit anti- HnRNP H Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat/293/K562 cells, using hnRNP H Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image hnRNP H antibody [N1C1] detects hnRNP H protein at nucleus by immunofluorescent analysis. Sample: A431 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: hnRNP H protein stained by hnRNP H antibody [N1C1] , diluted at 1:500. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] , diluted at 1:1000. Blue: Hoechst 33342 staining. ICC/IF Image hnRNP H antibody [N1C1] detects hnRNP H protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: hnRNP H protein stained by hnRNP H antibody [N1C1] , diluted at 1:200. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [B-5-1-2] , diluted at 1:10000. Blue: Hoechst 33342 staining. 100 μL 3 to 4 Days
$466.18
Details
Chicken Rabbit Un-conjugated IP, IHC, WB Immunohistochemical analysis of hnRNP H staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of hnRNP H expression in A549 (A), HeLa (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB WB Image hnRNP H antibody detects hnRNP H protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with hnRNP H antibody , diluted by 1:1000. 100 μL 3 to 4 Days
$466.18
Details
Cow Rabbit Un-conjugated IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-HNRNPH1 / hnRNP H antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this produc ... 100 μL 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Available
$363.46
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of hnRNP H expression in rat kidney lysate 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB ABIN6274296 staining HeLa cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. Western blot analysis of extracts from Jurkat cells using hnRNP H antibody. 100 μL 11 to 12 Days
$390.77
Details

Top referenced anti-HNRNPH1 Antibodies

  1. Human Polyclonal HNRNPH1 Primary Antibody for ICC, IF - ABIN151849 : Rauch, Ahlemann, Schaffrik, Mack, Ertongur, Andratschke, Zeidler, Lang, Gires: Allogenic antibody-mediated identification of head and neck cancer antigens. in Biochemical and biophysical research communications 2004 (PubMed)
    Show all 15 Pubmed References

  2. Human Polyclonal HNRNPH1 Primary Antibody for WB - ABIN1881424 : Van Dusen, Yee, McNally, McNally: A glycine-rich domain of hnRNP H/F promotes nucleocytoplasmic shuttling and nuclear import through an interaction with transportin 1. in Molecular and cellular biology 2010 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal HNRNPH1 Primary Antibody for ICC, IF - ABIN441646 : Wang, Ursu, Childs-Disney, Guertler, Yang, Bernat, Rzuczek, Fuerst, Zhang, Gendron, Yildirim, Dwyer, Rice, Petrucelli, Disney: The Hairpin Form of r(G4C2)exp in c9ALS/FTD Is Repeat-Associated Non-ATG Translated and a Target for Bioactive Small Molecules. in Cell chemical biology 2019 (PubMed)

More Antibodies against HNRNPH1 Interaction Partners

Human Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) interaction partners

  1. Sequestration of hnRNP H altered the splicing of target transcripts in C9 amyotrophic lateral sclerosis patients with GGGGCC expansion in the C9ORF72 gene. Here, the show that this signature also occurs in half of 50 postmortem sporadic, amyotrophic lateral sclerosis/frontotemporal dementia brains lacking GGGGCC expansion in the C9ORF72 gene.

  2. serum exosomal hnRNPH1 mRNA levels in hepatocellular carcinoma (HCC) patients were remarkably higher than in the other groups; exosomal hnRNPH1 mRNA levels in HCC patients were associated with the Child-Pugh classification, portal vein tumor emboli, lymph node metastasis, TNM stage and overall survival; findings suggested that serum exosomal hnRNPH1 mRNA could be an effective marker for HCC in high HBV prevalence areas

  3. Together, these data implicate C9ORF72 GGGGCC expansion-mediated sequestration of hnRNP H as a significant contributor to neurodegeneration in C9 amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.

  4. High HNRNPH1 expression is associated with castration-resistant prostate cancer.

  5. hnRNP H binds to two specific G-runs in exon 5a of ACHE and activates the distal alternative 3 splice site (ss) between exons 5a and 5b. Furthermore, hnRNP H competes for binding of CstF64 to the overlapping binding sites in exon 5a, and suppresses the selection of a cryptic polyadenylation site, which additionally ensures transcription of the distal 3 ss required for the generation of AChET isoform.

  6. The different alternative transcript variants of HNRNPH1 exhibited different expression changes during tumorigenesis. Its mRNA and protein were overexpressed in esophageal squamous cell carcinoma and associated with poorer differentiation of tumor cells.

  7. Our findings define novel roles for hnRNPH1 as a putative oncogene, splicing factor, and an auxiliary AR coregulator.

  8. Global splicing analysis with RNA-seq revealed that exons carrying the hnRNP H-binding GGGGG motif are predisposed to be skipped compared to those carrying the SRSF1-binding GGAGG motif in both human and mouse brains.

  9. vRSF3 and hnRNP H1 are the first splicing factors identified which regulate the production of these functionally distinct HER2 splice variants and therefore maybe important for the regulation of HER2 signaling.

  10. In pediatric T-acute lymphoblastic leukemia, we have identified 2 RNA processing genes, that is, HNRNPH1/5q35 and DDX3X/Xp11.3 as new MLLT10 fusion partners.

  11. These results support a working hypothesis that a late viral protein HPV16 L1, which is down regulated by hnRNP H early in the viral life cycle may provide an auto-regulatory positive feedback loop that allows the rapid production of HPV capsid proteins through suppression of the function of hnRNP H at the late stage of the viral life cycle.

  12. The REST N exon is a very versatile sequence with a complex array of splicing signals, and its activation in H69 cells depends on the relative amounts of hnRNP H and U2AF65.

  13. These results suggest that increased level of hnRNP-H and PDIA3 expression in Dengue virus infected THP1 cells assist in the viral replication by suppressing the TNF-alpha production.

  14. hnRNPH activity appears to be involved in the pathogenesis and progression of malignant gliomas as the centre of a splicing oncogenic switch

  15. spatial interactions of hnRNPH1, NF45, and C14orf166 with HCVc174 likely modulate HCV or cellular functions during acute and chronic HCV infection

  16. Insight on the crucial role of hnRNP H1 in the regulation of the alternative splicing of the rpL3 gene.

  17. Nuclear heterogeneous nuclear ribonucleo-protein H expression was related to survival in colorectal cancer.

  18. altered function of hnRNP H1/H2 in tumor cells is a novel determinant of aberrant thymidine phosphorylase splicing thereby resulting in acquired chemoresistance to TP-activated fluoropyrimidine anticancer drugs.

  19. the G-stretches within exon 9B regulate RAGE alternative splicing via interaction with hnRNP H

  20. working model in which rpL3 recruits hnRNP H1 and, through cooperation with other splicing factors, promotes selection of the alternative splice site

Mouse (Murine) Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) interaction partners

  1. These results define a novel contribution of Hnrnph1 to neurobehavioral dysfunction associated with dopaminergic neurotransmission.

  2. hnRNP C and hnRNP H bind to the 3'-UTR of the circadian clock gene Period 2 (mPer2).

  3. genome wide analysis of splicing events and gene expression regulated by hnRNPH/F in oligodendrocytes

  4. The hnRNP H1 can function as repressors of MOR translation dependent on the M4 sequence.

  5. hnRNPH activity appears to be involved in the pathogenesis and progression of malignant gliomas as the centre of a splicing oncogenic switch

HNRNPH1 Antigen Profile

Protein Summary

This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described

Gene names and symbols associated with HNRNPH1

  • heterogeneous nuclear ribonucleoprotein H1 (HNRNPH1) antibody
  • heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) antibody
  • heterogeneous nuclear ribonucleoprotein H1 S homeolog (hnrnph1.S) antibody
  • heterogeneous nuclear ribonucleoprotein H1 L homeolog (hnrnph1.L) antibody
  • heterogeneous nuclear ribonucleoprotein H1 (hnrnph1) antibody
  • heterogeneous nuclear ribonucleoprotein H1 (Hnrnph1) antibody
  • AI642080 antibody
  • E430005G16Rik antibody
  • Hnrnph antibody
  • HNRNPH1 antibody
  • hnrnph2 antibody
  • Hnrph antibody
  • Hnrph1 antibody
  • hnrph2 antibody
  • MGC69543 antibody
  • MGC78776 antibody
  • MGC80081 antibody
  • MGC130700 antibody
  • zgc:77712 antibody

Protein level used designations for HNRNPH1

heterogeneous nuclear ribonucleoprotein H , heterogeneous nuclear ribonucleoprotein H1 , heterogeneous nuclear ribonucleoprotein H1-like protein , heterogeneous nuclear ribonucleoprotein H1 (H) , heterogeneous nuclear ribonucleoprotein H2 (H') , heterogeneous nuclear ribonucleoprotein H1-like , heterogeneous nuclear ribonucleoprotein H-like , hnRNP H , ratsg1

GENE ID SPECIES
3187 Homo sapiens
395157 Gallus gallus
432071 Xenopus laevis
446758 Xenopus laevis
448155 Xenopus (Silurana) tropicalis
462329 Pan troglodytes
481455 Canis lupus familiaris
541202 Bos taurus
100067495 Equus caballus
100341383 Oryctolagus cuniculus
100415060 Callithrix jacchus
100467241 Ailuropoda melanoleuca
100519535 Sus scrofa
100540708 Meleagris gallopavo
100606289 Nomascus leucogenys
59013 Mus musculus
140931 Rattus norvegicus
704469 Macaca mulatta
101122518 Ovis aries
100726512 Cavia porcellus
101683493 Mustela putorius furo
402984 Danio rerio
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