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Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL) ELISA Kits

HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. Additionally we are shipping Heterogeneous Nuclear Ribonucleoprotein L-Like Antibodies (61) and Heterogeneous Nuclear Ribonucleoprotein L-Like Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HNRPLL 92906 Q8WVV9
HNRPLL 72692 Q921F4
HNRPLL 313842  
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Top Heterogeneous Nuclear Ribonucleoprotein L-Like ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Rabbit 1.0 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
$707.14
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Guinea Pig 1.0 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
$707.14
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Mouse 1.0 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
$707.14
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Rat 1.0 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
$707.14
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Human 1.0 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
$707.14
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Dog 1.0 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
$707.14
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Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
$707.14
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Sheep
  96 Tests 15 to 18 Days
$707.14
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Chicken
  96 Tests 15 to 18 Days
$707.14
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Goat
  96 Tests 15 to 18 Days
$707.14
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More ELISA Kits for Heterogeneous Nuclear Ribonucleoprotein L-Like Interaction Partners

Human Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL) interaction partners

  1. The findings demonstrate that the hnRNP L and LL proteins differentially control gene expression programs at multiple levels in the production of two physiologically important hormones.

  2. intronic editing of HNRPLL generates a novel splicing variant linked to cell proliferation

  3. Loss-of-function mutation of hnRNPLL disrupts peripheral T cell accumulation even in the absence of CD45 protein, indicating that hnRNPLL acts through an independent mechanism to promote peripheral T cell longevity.

  4. Participation of SRRF (Stromal RNA Regulating Factor) isoforms in post-transcriptional events in bone marrow stromal cells; an important role in regulation of the RNA expression that directs the bone marrow stromal cells differentiation pathway

  5. identification of heterogeneous ribonucleoprotein L-like (hnRNPLL) as a critical inducible regulator of CD45 alternative splicing

  6. These data establish that hnRNP LL plays a critical and unique role in the signal-induced regulation of CD45 and demonstrate the utility of cell-based screens for the identification of novel splicing regulatory factors.

Mouse (Murine) Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL) interaction partners

  1. HNRNPLL is a novel metastasis suppressor of colorectal cancer, and modulates alternative splicing of CD44 during epithelial-mesenchymal transition.

  2. Data suggest that hnRNPLL specifically associates with cytoplasmic PABPC1 in both T-lymphocytes and plasma cells; PABPC1 promotes binding of hnRNPLL to immunoglobulin H (IgH, heavy chain) mRNA and regulates switching from mIgH (membrane isoform) to sIgH (secreted isoform) in plasma cells. (hnRNPLL = heterogeneous nuclear ribonucleoprotein L-like protein; PABPC1 = cytoplasmic poly[A]-binding protein 1)

  3. We identify similar patterns of hnRNPLL-induced differential intron retention flanking alternative exons in 14 other genes, representing novel elements of the hnRNPLL-induced splicing program in T cells.

  4. Data indicate that the RNA-binding protein hnRNPLL has a critical role in tuning transcriptomes of terminally differentiating B lymphocytes.

  5. The splicing factor hnRNPLL and the transcription elongation factor ELL2 modulate the ratio of secred versus membrane-encoding Ighg2b transcripts at the expense of the secreted isoform.

  6. results highlight both overlapping and divergent roles for hnRNPLL between conventional T cells and NKT cells

  7. In T cells with no CD45 protein, hnRNPLL mutation diminishes peripheral T cell accumulation and demonstrates that hnRNPLL regulates T cell longevity independently from its effects on CD45 splicing.

  8. A single substitution in a memory-induced RNA-binding protein, hnRNPLL, destabilized an RNA-recognition domain that bound with micromolar affinity to RNA containing the Ptprc exon-silencing sequence.

Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL) Antigen Profile

Antigen Summary

HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC\; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008

Gene names and symbols associated with HNRPLL

  • heterogeneous nuclear ribonucleoprotein L like (HNRNPLL) antibody
  • heterogeneous nuclear ribonucleoprotein L-like (Hnrnpll) antibody
  • heterogeneous nuclear ribonucleoprotein L-like (HNRPLL) antibody
  • heterogeneous nuclear ribonucleoprotein L like (hnrnpll) antibody
  • heterogeneous nuclear ribonucleoprotein L-like (LOC100160547) antibody
  • Heterogeneous nuclear ribonucleoprotein L-like (hnrll) antibody
  • heterogeneous nuclear ribonucleoprotein L-like (LOC100542006) antibody
  • heterogeneous nuclear ribonucleoprotein L-like (LOC100638467) antibody
  • heterogeneous nuclear ribonucleoprotein L (LOC100647365) antibody
  • heterogeneous nuclear ribonucleoprotein L like (Hnrnpll) antibody
  • 2510028H02Rik antibody
  • 2810036L13Rik antibody
  • AI256697 antibody
  • AI852082 antibody
  • Hnrpll antibody
  • RGD1305861 antibody
  • srrf antibody

Protein level used designations for HNRPLL

stromal RNA regulating factor , stromal RNA-regulating factor , heterogeneous nuclear ribonucleoprotein L-like , Heterogeneous nuclear ribonucleoprotein L-like

GENE ID SPECIES
92906 Homo sapiens
72692 Mus musculus
313842 Rattus norvegicus
416702 Gallus gallus
470353 Pan troglodytes
475729 Canis lupus familiaris
534315 Bos taurus
100011229 Monodelphis domestica
100054138 Equus caballus
100151733 Xenopus (Silurana) tropicalis
100160547 Acyrthosiphon pisum
100194990 Salmo salar
100338555 Oryctolagus cuniculus
100393835 Callithrix jacchus
100542006 Meleagris gallopavo
100559832 Anolis carolinensis
100622737 Sus scrofa
100638467 Amphimedon queenslandica
100647365 Bombus terrestris
100713480 Cavia porcellus
101119633 Ovis aries
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