anti-Histamine N-Methyltransferase (HNMT) Antibodies

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. Additionally we are shipping HNMT Proteins (18) and HNMT Kits (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HNMT 3176 P50135
HNMT 140483 Q91VF2
HNMT 81676 Q01984
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Top anti-HNMT Antibodies at antibodies-online.com

Showing 10 out of 79 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-HNMT Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Fruit Fly Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$245.00
Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot analysis of HNMT Antibody (N-term) (ABIN388217) in Hela cell line lysates (35 µg/lane). HNMT(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with HNMT antibody (N-term) (ABIN388217), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of Hela whole cell lysates, using HNMT Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6277241 at 1/100 staining Human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IP, ELISA, WB 100 μL Log in to see 14 to 16 Days
$247.82
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.4 mL Log in to see 4 to 8 Days
$522.50
Details
Human Mouse Un-conjugated WB HNMT Antibody  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HNMT antibody detected the HNMT protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB Western Blot: HNMT Antibody [NBP1-69134] - Human Heart lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8 to 11 Days
$488.73
Details
Human Rabbit Un-conjugated IP, ELISA, WB 100 μL Log in to see 14 to 16 Days
$312.53
Details

More Antibodies against HNMT Interaction Partners

Human Histamine N-Methyltransferase (HNMT) interaction partners

  1. Histamine N-methyltransferase plays a central role in the degradation of the neurotransmitter histamine. Leucine 208 is a critical amino acid residue to maintain the structural integrity of the protein. Replacements by other amino acid residues have profound effects on stability and catalytic activity.

  2. NHMT polymorphisms are not associated with Parkinson's disease, ALS and multiple system atrophy in Chinese population.

  3. miR-223 participates in the pathogenesis of atopic dermatitis through upregulating HNMT indirectly to degrade the excessive histamine.

  4. The C allele for the HNMT polymorphism was associated with a lower degree of disability due to migraine (OR, 10.0; 95% CI, 2.65-37.6). In contrast, presence of the T allele (in heterozygous individuals) was associated with higher degree of disability (OR, 37.1; 95% CI, 4.37-315.2)

  5. This study shown that eight linked SNPs (r(2) = 1) in the HNMT gene were associated with sedation according to the generalized linear model, adjusted for age, gender and BMI (false-discovery-rate-adjusted p = 0.013).

  6. Genotype and allelic variant frequencies of HNMT rs11558538 SNP 205 restless legs syndrome (RLS) patients and 410 controls using a TaqMan assay: HNMT rs11558538 genotypes allelic variants frequencies were similar between RLS patients and controls and not influenced by gender, family history of RLS, or RLS severity. Some evidence that RLS patients carrying the genotype rs11558538TT had an earlier age at onset.

  7. The present meta-analysis confirms published evidence suggesting that the HNMT rs11558538 minor allele is related to a reduced risk of developing Parkinson disease

  8. this study shows that single nucleotide polymorphism is associated with the severity of allergic rhinitis in a group of Mexican children

  9. The T allele of rs3787429 exhibited protective effect against CHF under the dominant and additive models , while, for SNPs in HRH2, DAO, and HNMT, no significant associations were observed in the present study

  10. HNMT is identified as a novel gene responsible for intellectual disability. The consequences of the identified missense mutations on the protein function are discussed.

  11. HRH1-17 TT and HNMT-1639 TT genotypes were associated with the allergic asthma phenotype among African-American children and that the ABP 4107 GG genotype was associated with nonallergic asthma among white children.

  12. results suggest that the heterozygous Thr/Ile genotype at the HNMT-Thr105Ile locus and the minor Ile105 allele protect against Parkinson's disease and schizophrenia in Han Chinese.

  13. The polymorphisms of HNMT and HRH3 were irrelevant with breast cancer in the present study.

  14. The A939G HNMT polymorphism is associated with autoimmune MG, while no association with C314T SNP was found.

  15. The results of this study indicated that Histamine N-methyltransferase Thr105Ile polymorphism is associated Parkinson's disease.

  16. Lack of the association of HNMT Thr105Ile functional polymorphism with Alzheimer's disease is found.

  17. our results suggest that, despite the possible role of histamine in the inflammatory processes related with the pathogenesis of MS, HNMT polymorphism is not related with the risk for MS in Caucasian Spanish people

  18. This study do not support the HNMT Thr105Ile variant as a factor in disease development or a genetic link between the disorders.

  19. identification of several novel HNMT polymorphisms, identification of the HNMT core promoter

  20. for the histamine N-methyltransferase gene no differences in allele distribution were found in patients with food allergy and sprue compared to controls except for the 314t allele

Mouse (Murine) Histamine N-Methyltransferase (HNMT) interaction partners

  1. Genomic structure of the rat and mouse histamine N-methyltransferase gene

  2. decreasing expression over the time course of the skin pathological changes in MRL/lpr mice

HNMT Antigen Profile

Protein Summary

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Gene names and symbols associated with HNMT

  • histamine N-methyltransferase (HNMT) antibody
  • histamine N-methyltransferase (hnmt) antibody
  • histamine N-methyltransferase-like (LOC100228106) antibody
  • histamine N-methyltransferase (Hnmt) antibody
  • 1500031F01Rik antibody
  • AI788969 antibody
  • HMT antibody
  • hnmt antibody
  • HNMT-S1 antibody
  • HNMT-S2 antibody
  • zgc:100917 antibody

Protein level used designations for HNMT

histamine N-methyltransferase , HMT , Histamine N-methyltransferase

GENE ID SPECIES
424298 Gallus gallus
476133 Canis lupus familiaris
641310 Ovis aries
706713 Macaca mulatta
742204 Pan troglodytes
779808 Xenopus (Silurana) tropicalis
100196123 Salmo salar
100228106 Taeniopygia guttata
100347399 Oryctolagus cuniculus
100528906 Ictalurus punctatus
3176 Homo sapiens
140483 Mus musculus
81676 Rattus norvegicus
613413 Bos taurus
100135537 Cavia porcellus
100174618 Pongo abelii
445242 Danio rerio
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