anti-Histamine Receptor H2 (HRH2) Antibodies

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Additionally we are shipping HRH2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HRH2 3274 P25021
HRH2 15466  
HRH2 25461 P25102
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Top anti-HRH2 Antibodies at

Showing 10 out of 121 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of Histamine H2 Receptor staining in COLO205 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of Histamine H2 Receptor expression in HEK293T (A), COLO205 (B), NIH3T3 (C), H9C2 (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of LOVO cells, using HRH2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Goat Un-conjugated ELISA, WB Western Blot: Histamine H2 R Antibody [NBP1-78790] - (0.1ug/ml) staining of Duodenum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: Histamine H2 R Antibody [NLS1175] - Analysis of anti-HRH2 / Histamine H2 Receptor antibody with human stomach, parietal cells. 0.05 mL Log in to see 10 to 13 Days
Human Goat Un-conjugated IHC, ELISA, WB   100 μg Log in to see 6 to 7 Days
Human Rabbit Un-conjugated EIA, WB Western blot analysis of HRH2 Antibody (Center) in Uterus cell line lysates (35ug/lane). This demonstrates the HRH2 antibody detected the HRH2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
Mouse Rabbit Un-conjugated IF, IHC, WB Western blot analysis of rat basophilic leukemia cells (RBL) (lanes 1 and 3) and rat brain lysates (lanes 2 and 4): 1, 2. Anti-Rat H2 Histamine Receptor (extracellular) antibody, (1:200). 3, 4. Anti- Rat H2 Histamine Receptor (extracellular) antibody, preincubated with the control peptide antigen. Expression of H2 Histamine Receptor in rat stomach Immunohistochemical staining of paraffin embedded section of rat stomach using Anti-Rat H2 Histamine Receptor (extracellular) antibody, (1:100). H2R (brown staining) is expressed in parietal cells (arrows) of the gastric glands. Hematoxilin is used as the counterstain. 50 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: Histamine H2 R Antibody [NBP1-86082] - Immunohistochemical staining of human small intestine shows strong cytoplasmic positivity in few glandular cells. 0.1 mL Log in to see 10 to 13 Days

HRH2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus) , , , ,

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Top referenced anti-HRH2 Antibodies

  1. Human Polyclonal HRH2 Primary Antibody for IHC, ELISA - ABIN185463 : Nakane, Sonobe, Watanabe, Nakano: Histamine: its novel role as an endogenous regulator of Con A-dependent T cell proliferation. in Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2004 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal HRH2 Primary Antibody for IHC, IHC (p) - ABIN4317558 : Tanaka, Kochi, Shirakami, Mori, Kurata, Watanabe, Moriwaki, Shimizu: Cimetidine and Clobenpropit Attenuate Inflammation-Associated Colorectal Carcinogenesis in Male ICR Mice. in Cancers 2016 (PubMed)

  3. Human Polyclonal HRH2 Primary Antibody for IHC (p) - ABIN4317556 : Dagli, Goksu, Eryilmaz, Mocan Kuzey, Bayazit, Gun, Gocer: Expression of histamine receptors (H(1), H(2), and H(3)) in the rabbit endolymphatic sac: an immunohistochemical study. in American journal of otolaryngology 2007 (PubMed)

More Antibodies against HRH2 Interaction Partners

Human Histamine Receptor H2 (HRH2) interaction partners

  1. Pharmacological or genetic modulations of H2 and H4 HRs (H2R and H4R) not only suppressed gefitinib-induced cytostasis and differentiation of AML cells but also blocked EGFR and ERK1/2 inhibition in MDA-MB-231 cells

  2. The T allele of rs3787429 exhibited protective effect against CHF under the dominant and additive models , while, for SNPs in HRH2 (show DHX15 Antibodies), DAO (show ABP1 Antibodies), and HNMT (show HNMT Antibodies), no significant associations were observed in the present study

  3. High constitutive Akt2 (show AKT2 Antibodies) activity in U937 promonocytes: effective reduction of Akt2 (show AKT2 Antibodies) phosphorylation by the histamine H2-receptor and the beta2-adrenergic receptor (show ADRB2 Antibodies)

  4. Lack of Association between rs2067474 Polymorphism in Histamine Receptor H2 Gene and Breast Cancer in Chinese Han Population

  5. But carriers of one or three copies of HRH1 (show DHX8 Antibodies) (5% of individuals), HRH2 (show DHX15 Antibodies) (1.1%) and HRH4 (show HRH4 Antibodies) genes (0.9%) were also identified.

  6. The inhibitory effects of histamine on reactive oxygen species production in whole blood phagocytes are caused by H2R rather than H4R (show HRH4 Antibodies) histamine receptors.

  7. HR signaling through cyclic AMP (show APRT Antibodies) and exchange protein directly activated by cyclic AMP (show APRT Antibodies) was required for the histamine effect on LPS (show IRF6 Antibodies)-induced monocyte-derived dendritic cells responses

  8. rs2607474 GG homozygote confers a significantly increased risk for age- and inflammation-related DAPK (show DAPK1 Antibodies) and CDH1 (show CDH1 Antibodies) methylation in gastric epithelium.

  9. HR2 (show MFN1 Antibodies) receptor is involved in histamine-induced GDF-15 (show GDF15 Antibodies) expression.

  10. The results suggest that HRH2 (show DHX15 Antibodies) -1018 GG homozygote is a risk factor for the severity of gastric mucosal atrophy under the influence of H. pylori infection, especially in older subjects.

Mouse (Murine) Histamine Receptor H2 (HRH2) interaction partners

  1. Ability of probiotic L. reuteri to suppress colitis depends on the presence of a bacterial histidine decarboxylase (show HDC Antibodies) gene(s) in the intestinal microbiome, consumption of a histidine-containing diet, and signaling via the histamine H2 receptor (H2R).

  2. required for IL-6 (show IL6 Antibodies) and IL-17 (show IL17A Antibodies) mucosal responses to intestinal histamine-secreting microbes

  3. histamine receptor H1 (show HRH1 Antibodies) and histamine receptor H2 reciprocally regulate inflammation in the ligation-induced arteriosclerosis

  4. Data show that experimental allergic encephalomyelitis (EAE) severity and in histamine H2 receptor (H2RKO) mice expressing H2R exclusively in T cells become equal to those in wild-type B6 mice only when pertussis toxin is used to elicit disease.

  5. H2R activation exaggerates myocardial I/R injury by promoting myocardial mitochondrial dysfunction and by increasing cardiac vascular endothelial permeability.

  6. Data suggest histamine stimulates proliferation of Leydig tumor cells via activation of HRH2 and a transient increase in intracellular cAMP levels. Normal/immature Leydig cells and progenitor Leydig cells exhibit very low levels of HDC (show HDC Antibodies) expression.

  7. Histamine reduced the alpha-CD3 (show CD3E Antibodies)-induced interferon-gamma (IFN-gamma (show IFNG Antibodies)) production of CD4 (show CD4 Antibodies)+ cells via the histamine H-receptor.

  8. A previously unidentified role for H2R establishes a synergy between endogenous histamine and interleukin (IL)-4 (show IL4 Antibodies) that supports eosinophilic recruitment to the lung.

  9. HR2 (show MFN1 Antibodies) immunoreactivity was observed on the processes and cell bodies of the primary glial cells of the mammalian retina, the Muller cells.

  10. decreasing expression on the mast cells within skin lesions of MRL/lpr (show FAS Antibodies) mice

Rhesus Monkey Histamine Receptor H2 (HRH2) interaction partners

  1. Histamine H2 receptor mRNA is localized in cone inner segments from retina.

HRH2 Antigen Profile

Protein Summary

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HRH2

  • histamine receptor H2 (HRH2) antibody
  • histamine receptor H2 (Hrh2) antibody
  • histamine receptor H2a (hrh2a) antibody
  • histamine receptor H 2 (Hrh2) antibody
  • H2R antibody
  • HH2R antibody
  • HRH2 antibody

Protein level used designations for HRH2

HH2R , gastric receptor 1 , gastric receptor I , histamine H2 receptor , H2R , histamine receptor subtype H2 , histamine receptor H2

3274 Homo sapiens
15466 Mus musculus
403812 Canis lupus familiaris
427635 Gallus gallus
443190 Ovis aries
471750 Pan troglodytes
521257 Bos taurus
695226 Macaca mulatta
735303 Danio rerio
100338726 Oryctolagus cuniculus
25461 Rattus norvegicus
100729734 Cavia porcellus
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