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The protein encoded by HDAC10 belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones.
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Human Polyclonal HDAC10 Primary Antibody for WB - ABIN223305
Bali, Pranpat, Bradner, Balasis, Fiskus, Guo, Rocha, Kumaraswamy, Boyapalle, Atadja, Seto, Bhalla: Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors. in The Journal of biological chemistry 2005
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Human Polyclonal HDAC10 Primary Antibody for IHC (p), IHC - ABIN407684
Tiwari, Dharmarajan, Shivanna, Otteson, Belecky-Adams: Histone deacetylase expression patterns in developing murine optic nerve. in BMC developmental biology 2014
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Human Polyclonal HDAC10 Primary Antibody for WB - ABIN387962
Fischer, Cai, Bhatia, Asselbergs, Song, Terry, Trogani, Widmer, Atadja, Cohen: Isolation and characterization of a novel class II histone deacetylase, HDAC10. in The Journal of biological chemistry 2002
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this study demonstrated that HDAC10 localizes and functions in the cytoplasm of lung cancer cells, thereby underscoring its potential role in the diagnosis and treatment of lung cancer
HDAC10 regulates cyclin A2 (show CCNA2 Antibodies) expression by deacetylating histones near the let-7 promoter.
study identifies an HDAC10-mediated regulatory mechanism controlling the DNA mismatch repair function of MSH2 (show MSH2 Antibodies).
Suggest HDAC10 expression as a prognostic marker for gastric cancer.
this study is describing HDAC10 as a promoter of autophagy-mediated survival in neuroblastoma (show ARHGEF16 Antibodies) cells and identifying this HDAC (show HDAC3 Antibodies) isozyme as a druggable regulator of advanced-stage tumor cell survival.
HDAC10 suppresses expression of matrix metalloproteinase (MMP) 2 (show MMP2 Antibodies) and 9 genes, which are known to be critical for cancer cell invasion and metastasis
results demonstrate that HDAC10 protects cancer cells from cytotoxic agents by mediating autophagy and identify this HDAC (show HDAC3 Antibodies) isozyme as a druggable regulator of advanced-stage tumor cell survival
HDAC10 is involved in transcriptional downregulation of TXNIP (show TXNIP Antibodies), leading to altered reactive oxygen species signaling in human gastric cancer cells.
Results not only show that HDAC10 regulates melanogenesis but also demonstrate that the transcriptional activities of Pax3 (show PAX3 Antibodies) and KAP1 (show CDKN3 Antibodies) are intimately linked to their acetylation status.
another histone deacetylase (show HDAC1 Antibodies)
The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
histone deacetylase 10