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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Additionally we are shipping Homeobox A11 Proteins (5) and many more products for this protein.
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High expression of lncRNA HOXA11-AS promotes breast cancer invasion and metastasis by affecting EMT (show ITK Antibodies).
HOXA11 silencing suppressed osteosarcoma cell proliferation, invasion and induced cell arrest.
Results show that aberrant hypermethylation and the methylation-induced down-regulation of HOXA11 may promote lung adenocarcinoma progression.
Hypermethylation of HOXA11 is an independent prognostic biomarker in breast cancer. Suggest HOXA11 as a potential tumor suppressor.
The treatment resistance induced by the underexpression of HOXA11 can contribute to a poor prognosis in GBM.
These results suggest that mutations in the coding sequence of HOXA11 might not be a common cause of cryptorchidism, while common polymorphisms in the HOXA11 gene might contribute to the risk of developing unilateral cryptorchidism.
demonstrated that HOXA11-antisense(AS) functioned as a molecular sponge for miR (show MLXIP Antibodies)-124, and overexpression of miR (show MLXIP Antibodies)-124 attenuated the proliferation and invasion-promoting effect of HOXA11-AS
Bioinformatics prediction forecast that miR (show MLXIP Antibodies)-140-5p directly targeted HOXA11-antisense RNA at 3'-UTR (show UTS2R Antibodies), which was confirmed by luciferase reporter assay
HOXA11-AS functions as a competing endogenous RNA.
our study demonstrated that HOXA11 function as a tumor suppressor in renal cell carcinoma (show MOK Antibodies)
the derived functional cooperativity between HOXA11 and FOXO1 (show FOXO1 Antibodies) is due to derived allosteric regulation of HOXA11 by FOXO1 (show FOXO1 Antibodies).
On the basis of the polydactyly that we observed after expression of Hoxa11 in distal limbs, we propose that the evolution of Hoxa11 regulation contributed to the transition from polydactyl limbs in stem-group tetrapods to pentadactyl limbs in extant tetrapods.
Shox2 (show SHOX2 Antibodies) expression restricted to the proximal limb along with Hoxd9 (show HOXD9 Antibodies) and Hoxa11 expression, juxtaposing the distal expression of Hoxa13 (show HOXA13 Antibodies) and Hoxd13 (show HOXD13 Antibodies).
Hoxa-11 maintains cell proliferation in the mouse gubernaculum to facilitate testicular descent.
Hoxa11 and Hoxd11 (show HOXD11 Antibodies) regulate chondrocyte differentiation upstream of Runx2 (show RUNX2 Antibodies) and Shox2 (show SHOX2 Antibodies) in mice.
Results reveal that Hoxa11 knockdown in the uterosacral ligaments and uterus increases extracellular matrix degradation.
Data show that the extra-embryonic function of Hoxa10 (show HOXA10 Antibodies), -11, and -13 genes stems from their specific expression in the allantois, an extra-embryonic hallmark of amniote vertebrates.
Hox11 (show TLX1 Antibodies) genes (Hoxa11, Hoxc11 (show HOXC11 Antibodies) and Hoxd11 (show HOXD11 Antibodies)) co-regulate and coordinate the development of zeugopod skeletal elements and adjacent elbow and knee joints, and dictate joint identity, morphogenesis and anatomical and functional organization.
mice individually mutant for Hoxa11 or Hoxd11 (show HOXD11 Antibodies) show no discernible kidney abnormalities. Hoxa11/Hoxd11 (show HOXD11 Antibodies) double mutants, however, demonstrate hypoplasia of the kidneys
Hoxa11 is required for proper cellular proliferation and apoptotic responses in the developing neonatal uterus.
The TM-induced characteristic changes in the expression pattern of Hoxa11 and Bmp4 (show BMP4 Antibodies) on GDs (show PAEP Antibodies) 10 and/or 11 were not noted
re-expression of hoxa11 and hoxa13 (show HOXA13 Antibodies) in the froglet blastema is initiated although the subsequent proximal-distal patterning, including separation of the hoxa11 and hoxa13 (show HOXA13 Antibodies) expression domains, is disrupted.
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.
homeo box 1I
, homeobox protein HOXA11
, homeobox protein Hox-1I
, homeobox protein Hox-A11
, homeo box A11
, homeobox protein Hox-1.9
, homeodomain-containing protein
, homeobox A11
, homeo box A10
, homeobox protein A10
, homeobox containing transcription factor
, homeobox protein Hox A11