Homeobox B4 (HOXB4) ELISA Kits

HOXB4 is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. Additionally we are shipping Homeobox B4 Antibodies (93) and Homeobox B4 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HOXB4 3214 P17483
Anti-Mouse HOXB4 HOXB4 15412 P10284
Anti-Rat HOXB4 HOXB4 497988  
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Top Homeobox B4 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days

More ELISA Kits for Homeobox B4 Interaction Partners

Human Homeobox B4 (HOXB4) interaction partners

  1. Data suggests that an impaired capacity of eutopic and ectopic endometrial tissue to upregulate levels of HOXB4 during the proliferative phase may play a role in the pathogenesis of endometriosis and that further downregulation of HOXB4 may enhance ectopic implant invasiveness.

  2. Authors observed that induced expression of HOXB4 in the UW473 cell line significantly reduced in vitro cell proliferation and migration capability of UW473 cells with no effect on the in vivo tumorigenicity.

  3. Study revealed that HOXB4 was highly expressed in ovarian cancer cells. HOXB4 silencing enhanced the cytotoxic effect of Taxol and DDP (show TIMM8A ELISA Kits) by downregulating ABC (show ABCB6 ELISA Kits) transporters via inhibition of the PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) signaling pathway. These results for the first time elucidated the critical roles and molecular basis of HOXB4 underlying drug resistance in ovarian cancer cells.

  4. HOXB4 knockout led to downregulation of P-glycoprotein, multidrug resistance-associated protein 1 (show ABCC1 ELISA Kits) and breast cancer resistance protein expression and PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) signaling activity, suggesting that repression of HOXB4 might be a key point to reverse Multidrug resistance of K562/ADM (show ADM ELISA Kits) cells.

  5. This study provides novel evidences of the mechanisms integrating Notch (show NOTCH1 ELISA Kits) and TNF-alpha (show TNF ELISA Kits) signaling in the transcriptional induction of GATA3 (show GATA3 ELISA Kits) and HOXB4.

  6. Increased expression of HOXB4 in human embryonic stem cells enhances the production of hematopoietic Progenitors but does not effect the maturation of red blood cells.

  7. The analysis of HOX expression in primary mesothelioma tumors indicated that these cells could also be sensitive to the disruption of HOX activity by HXR9, and that the expression of HOXB4 is strongly associated with overall survival

  8. HOXA4 increases short-term repopulation to higher levels than HOXB4, which may involve Notch (show NOTCH1 ELISA Kits) signaling to induce self-renewal of primitive hematopoietic cells

  9. showed that OAC1 treatment led to OCT4 (show POU5F1 ELISA Kits)-mediated upregulation of HOXB4

  10. decreased methylation at HOXB3 and HOXB4 was associated with increased gene expression of both HOXB genes specific to the mid-risk AML (show RUNX1 ELISA Kits), while increased DNA methylation at DCC (show DCC ELISA Kits) distinctive to the high-risk AML (show RUNX1 ELISA Kits) was associated with increased gene expression

Mouse (Murine) Homeobox B4 (HOXB4) interaction partners

  1. Our data reveal a route to establishing functional multipotent HSCs that exploits aspects of in vitro differentiation, transcription factor re-specification with HoxB4 to enhance self-renewal, and Notch (show NOTCH1 ELISA Kits)-mediated lineage specification

  2. can amplify long-term repopulating hematopoietic stem cells in a controlled way. This characteristic depends on a proline-rich sequence near the N terminus, which is unique among HOX genes and highly conserved in higher mammals

  3. Data suggest that the homeobox B4 protein (HoxB4) and signal transducer and activator of transcription 3 (STAT3 (show STAT3 ELISA Kits)) signals are functionally redundant for hematopoietic stem cells (HSCs) self-renewal rather than exerting independent effects.

  4. these studies define the transcriptional pathways involved in HOXB4 HSC expansion in vivo and identify repression of Prdm16 (show PRDM16 ELISA Kits) transcription as a mechanism by which expanding HSCs avoid leukemic transformation.

  5. Hoxb4 favours the maintenance and increase of the CD4 (show CD4 ELISA Kits) central memory phenotype T cell population.

  6. The results show a novel role for DNA methylation in the alternative promoter usage at the Runx1 (show RUNX1 ELISA Kits) locus and identify HOXB4 as a direct activator of the Runx1 (show RUNX1 ELISA Kits) P1 promoter.

  7. Loss of Scmh1 caused derepression of Hoxb4 and Hoxa9, direct targets of Polycomb-group complex 1-mediated transcriptional silencing in hematopoietic cells.

  8. HOXB4 activation can generate a paracrine as well as a cell autonomous effect on hematopoietic differentiation.

  9. HoxB4 reprograms a set of key regulator genes to facilitate the maturation of developing hematopoietic stem cells into repopulating cells

  10. Hoxb4 expression therefore would not appear to correlate with the cycling status of fetal liver hematopoietic stem cells(HSCs), although highly proliferative HSCs from young BM show strong Hoxb4 expression.

Zebrafish Homeobox B4 (HOXB4) interaction partners

  1. the similarity of hoxb3a/Hoxa3 regulatory mechanisms reflect the shared descent of both genes from a single ancestral paralog, expression of both genes in the posterior hindbrain and spinal cord in embryo

Homeobox B4 (HOXB4) Antigen Profile

Antigen Summary

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.

Gene names and symbols associated with Homeobox B4 (HOXB4) ELISA Kits

  • homeobox B4 (HOXB4) antibody
  • homeobox B4 (Hoxb4) antibody
  • homeobox B4 (hoxb4) antibody
  • homeobox B4 S homeolog (hoxb4.S) antibody
  • homeobox B4a (hoxb4a) antibody
  • hox4 protein (hox4) antibody
  • homeo box B4 (Hoxb4) antibody
  • hoxb4a protein (hoxb4a) antibody
  • Chox-Z antibody
  • FrHOXB-4 antibody
  • hox-2.6 antibody
  • HOX-B4 antibody
  • hox2 antibody
  • hox2f antibody
  • HOXB4 antibody
  • HoxB4a antibody
  • RGD1560113 antibody
  • XHox-b4 antibody
  • Z-17 antibody
  • ZF-13 antibody
  • zf13 antibody

Protein level used designations for Homeobox B4 (HOXB4) ELISA Kits

homeo box 2F , homeo box B4 , homeobox protein Hox-2.6 , homeobox protein Hox-2F , homeobox protein Hox-B4 , homeobox protein Hox-Z , homeobox B4 , xhox-1A , Hoxb4a variant 2 , etID309956.3 , homeobox gene B-4 , homeobox protein Hox-B4a , homeobox protein Zf-13 , hox4 protein , hoxb4a protein , LOW QUALITY PROTEIN: homeobox protein Hox-B4 , FrHOXB-4 , Homeobox protein Hox-B4a , homeobox protein HoxB4a

3214 Homo sapiens
15412 Mus musculus
396230 Gallus gallus
548393 Xenopus (Silurana) tropicalis
608915 Canis lupus familiaris
734796 Xenopus laevis
749218 Pan troglodytes
768240 Bos taurus
30340 Danio rerio
445807 Ciona intestinalis
497988 Rattus norvegicus
100049485 Oryzias latipes
100719955 Cavia porcellus
101061711 Takifugu rubripes
101096120 Felis catus
Selected quality suppliers for Homeobox B4 (HOXB4) ELISA Kits
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