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HOXC5 belongs to the homeobox family of genes. Additionally we are shipping Homeobox C5 Antibodies (47) and many more products for this protein.
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The A17860G located in 3'flanking sequence of HOXC5 gene is associated with simple congenital heart disease; the haplotype of 3 SNPs may be linked with the susceptible gene of simple CHD (show CHDH Proteins).
Late Hoxc5 removal preserves phrenic motor columnar organization but depletes phrenic motor column number and branches.
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC5, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants have been described for HOXC5. The transcript variant which includes the shared exon apparently doesn't encode a protein. The protein-coding transcript variant contains gene-specific exons only.
, homeobox gene C-5
, homeobox protein Hox-3.4
, homeobox protein Hox-C5a
, homeobox protein Zf-25
, homeobox protein Hox-C5
, homeo box C5
, homeobox protein CP11
, homeobox protein Hox-3D
, homeobox protein Hox-6.2