anti-Homeobox D10 (HOXD10) Antibodies

HOXD10 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. Additionally we are shipping HOXD10 Proteins (12) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HOXD10 3236 P28358
HOXD10 15430 P28359
HOXD10 303991  
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Top anti-HOXD10 Antibodies at antibodies-online.com

Showing 10 out of 80 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-HOXD10 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  PANC1 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN308427 (0.2 µg/mL) staining of Human Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN308427 (3.8 µg/mL) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from K562/RAW264.7 cells, using HOXD10 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of HOXD10 Antibody (C-term) in mouse liver tissue lysates (35ug/lane). This demonstrates the HOXD10 antibody detected the HOXD10 protein (arrow). Western blot analysis of HOXD10 Antibody (C-term) in Zebrafish brain tissue lysates (35ug/lane). This demonstrates the HOXD10 antibody detected the HOXD10 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Bat Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 11 to 14 Days
$484.00
Details
Cow Goat Un-conjugated IHC (p), WB   0.1 mg 4 to 8 Days
$462.00
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis of HoxD10 using K562 whole cell lysates ABIN6272322 staining K562 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. 100 μL 11 to 12 Days
$390.77
Details
Mouse Rabbit Un-conjugated WB Western blot analysis in mouse liver tissue lysates (35ug/lane). Western blot analysis in zebra fish brain tissue lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis in NCI-H292 cell line lysates (35ug/lane). Mouse Hoxd10 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
$515.63
Details

Top referenced anti-HOXD10 Antibodies

  1. Human Polyclonal HOXD10 Primary Antibody for ELISA, IHC - ABIN451732 : Myers, Charboneau, Cheung, Hanks, Boudreau: Sustained expression of homeobox D10 inhibits angiogenesis. in The American journal of pathology 2002 (PubMed)

More Antibodies against HOXD10 Interaction Partners

Human Homeobox D10 (HOXD10) interaction partners

  1. HOXD10 was suppressed in colon adenocarcinoma cells, which down-regulated RHOC/AKT/MAPK pathway.

  2. Results show that HOXD10 promoter is hypermethylated in papillary thyroid cancer (PTC) tissues and its mRNA expression decreased. Moreover, the hypermethylation of HOXD10 was associated with invasion of the primary tumor. Further data provide evidence that the epigenetic suppression of the HOXD10 gene may play a role in the tumorigenesis of PTC.

  3. Results show that HOXD10 is frequently methylated in human hepatocellular carcinoma (HCC), and the expression of HOXD10 is regulated by promoter region methylation. HOXD10 suppresses HCC cell growth both in vitro and in vivo. HOXD10 suppresses human HCC by inhibiting ERK signaling.

  4. our data suggest that the loss of HoxD10 function is common and may thus result in a progressive phenotype in PCa. HoxD10 may function as a biomarker that differentiates patients with BCR disease from the ones that are not after radical prostatectomy, implicating its potential as a therapeutic target.

  5. Knock down of the dickkopf WNT signaling pathway inhibitor 2 (DKK2) resulted in a significant suppression of HOXD10, HOXD11 and HOXD13 while over-expression of DKK2 and stimulation with factors of the WNT signaling pathway.

  6. By treating LECs with VEGF-C156S and analyzing subsequent changes in gene expression, we identified several 'immediate early' transcription factors that showed a rapid transient upregulation VEGFR-3 stimulation. these results reveal an important and unanticipated role of HOXD10 in the regulation of VEGFR-3 signaling in lymphatic endothelial cells, and in the control of lymphangiogenesis and permeability.

  7. Knockdown of HOXD10 in renal cells also resulted in increased resistance to colistin cytotoxicity.

  8. High expression of HOXD10 is associated with laryngeal squamous cell carcinoma.

  9. Low HOXD10 promotes migration and invasion in gastric cancer.

  10. These results suggested that HOXD10 may be a putative suppressor gene and can act as a prognostic marker and potentially a novel therapeutic target for cholangiocellular carcinoma.

  11. miR-23a was upregulated in glioma. This overexpression promoted glioma cell invasion, probably by modulating MMP-14 via directly inhibiting the expression of HOXD10.

  12. POU2F1 activity regulates HOXD10 and HOXD11 gene expression in head and neck squamous cell carcinoma, promoting a proliferative and invasive phenotype.

  13. Downregulation of the HOXD10 gene expression was associated with breast cancer.

  14. KLF4 and HOXD10 were identified as direct targets of miR-10b in bladder cancer cells

  15. It is a member of the HOX gene family. HOX genes are the main regulatory genes that directly influence organogenesis and maintain the function of differentiated tissues

  16. MicroRNA-10b promotes nucleus pulposus cell proliferation through RhoC-Akt pathway by targeting HOXD10 in intervetebral disc degeneration.

  17. HOXD10 expression varies by stage of disease and produces differential effects in head and neck squamous cell carcinoma.

  18. TBX1 can alter TGF-beta/BMP, an important signaling pathway, through interacting with HOXD10. Above findings may shed light on the mechanism of TBX1 mutations leading to renal malformations found in patients carrying a 22q11 deletion.

  19. downregulation of HOXD10 expression by miR-10b overexpression may induce an increase of pro-metastatic gene products, such as MMP14 and RHOC, and contribute to the acquisition of metastatic phenotypes in epithelial ovarian cancer cells

  20. HoxD10 potentially functions as a tumor suppressor that is inactivated through promoter hypermethylation in gastric cancer.

Mouse (Murine) Homeobox D10 (HOXD10) interaction partners

  1. genes compete for a remote enhancer that recognizes the locus in a polar fashion, with a preference for 5' extremity; modifications in either number or topography of Hoxd loci induced regulatory reallocations affecting both number and morphology of digits

  2. The organization and distribution of lumbar motor neurons was examined in the spinal cords of Hoxd10/Hoxa10 double mutant animals. Double mutant mice have decreased numbers of lumbar motor neurons in both the medial and lateral motor columns.

  3. show that the intracellular domain of Notch1, transcription factor Ets-1, and homeo box D10 (HOXD10).pre B-cell leukemia transcription factor 1(PBX1b).PREP1 activate the rat renin promoter cooperatively

  4. The three paralogous genes, Hoxa10, Hoxc10, and Hoxd10, are all expressed in the lumbar spinal cord and have distinct expression patterns

  5. Gli3 mutant limbs are characterized by a severe polydactyly and associated ectopic anterior expression of 5'Hoxd genes.

  6. Hoxc10 and Hoxd10 play key roles in establishing lumbar motoneuron columnar, divisional and motor pool identity

HOXD10 Antigen Profile

Protein Summary

This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as 'rocker-bottom foot' deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.

Gene names and symbols associated with anti-Homeobox D10 (HOXD10) Antibodies

  • homeobox D10 (HOXD10) antibody
  • homeobox D10 (Hoxd10) antibody
  • homeo box D10 (Hoxd10) antibody
  • homeobox D10 L homeolog (hoxd10.L) antibody
  • homeobox D10 (hoxd10) antibody
  • homeobox D10a (hoxd10a) antibody
  • AI385591 antibody
  • AI874987 antibody
  • hox-4.4 antibody
  • Hox-4.5 antibody
  • Hox-5.3 antibody
  • HOX-D10 antibody
  • hox4 antibody
  • hox4d antibody
  • hox4e antibody
  • hoxd-10 antibody
  • hoxd10 antibody
  • HoxD10a antibody
  • Xhoxd10 antibody
  • z-82 antibody

Protein level used designations for anti-Homeobox D10 (HOXD10) Antibodies

homeo box 4D , homeo box D10 , homeobox protein Hox-4D , homeobox protein Hox-4E , homeobox protein Hox-D10 , homeobox protein Hox-4.5 , homeobox protein Hox-5.3 , homeobox D10 , homeobox protein, Hoxd10 , homeobox protein Hox-D10-like , homeobox gene D-10 , homeobox protein Hox-C10 , homeobox protein Hox-D10a , hox-C10 , Homeobox protein Hox-D10a , homeobox protein HoxD10a

GENE ID SPECIES
3236 Homo sapiens
15430 Mus musculus
303991 Rattus norvegicus
399032 Xenopus laevis
488415 Canis lupus familiaris
540251 Bos taurus
700318 Macaca mulatta
739607 Pan troglodytes
771246 Gallus gallus
100019168 Monodelphis domestica
100038085 Xenopus (Silurana) tropicalis
100066123 Equus caballus
100174239 Pongo abelii
100408283 Callithrix jacchus
100515344 Sus scrofa
100579168 Oryctolagus cuniculus
100586307 Nomascus leucogenys
30404 Danio rerio
101065273 Takifugu rubripes
100720292 Cavia porcellus
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