anti-Homeobox D10 (HOXD10) Antibodies

HOXD10 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. Additionally we are shipping HOXD10 Proteins (12) and HOXD10 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HOXD10 3236 P28358
HOXD10 15430 P28359
HOXD10 303991  
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Top anti-HOXD10 Antibodies at antibodies-online.com

Showing 10 out of 78 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-HOXD10 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  PANC1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN308427 (0.2 µg/mL) staining of Human Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN308427 (3.8 µg/mL) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Log in to see 6 to 7 Days
$429.62
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from K562/RAW264.7 cells, using HOXD10 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of HOXD10 Antibody (C-term) in mouse liver tissue lysates (35ug/lane). This demonstrates the HOXD10 antibody detected the HOXD10 protein (arrow). Western blot analysis of HOXD10 Antibody (C-term) in Zebrafish brain tissue lysates (35ug/lane). This demonstrates the HOXD10 antibody detected the HOXD10 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Bat Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 11 to 14 Days
$484.00
Details
Mouse Rabbit Un-conjugated WB HOXD10 Antibody (C-term) (ABIN656539) western blot analysis in mouse liver tissue lysates (35 µg/lane). This demonstrates the HOXD10 antibody detected the HOXD10 protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated IHC (p), WB Mouse Hoxd10 Antibody (Center) (ABIN658230) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the Hoxd10 antibody detected the Hoxd10 protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Cow Goat Un-conjugated IHC (p), WB   0.1 mg Log in to see 8 to 11 Days
$462.00
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis of HoxD10 using K562 whole cell lysates ABIN6272322 staining K562 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. 100 μL Log in to see 11 to 12 Days
$390.77
Details

Top referenced anti-HOXD10 Antibodies

  1. Human Polyclonal HOXD10 Primary Antibody for ELISA, IHC - ABIN451732 : Myers, Charboneau, Cheung, Hanks, Boudreau: Sustained expression of homeobox D10 inhibits angiogenesis. in The American journal of pathology 2002 (PubMed)

  2. Human Polyclonal HOXD10 Primary Antibody for IHC (p), WB - ABIN658230 : Yang, Zhou, Mi, Ma, Fan, Ning, Wang, Wei, Zhao, Li: HOXD10 acts as a tumor-suppressive factor via inhibition of the RHOC/AKT/MAPK pathway in human cholangiocellular carcinoma. in Oncology reports 2015 (PubMed)

More Antibodies against HOXD10 Interaction Partners

Human Homeobox D10 (HOXD10) interaction partners

  1. Results show that HOXD10 promoter is hypermethylated in papillary thyroid cancer (PTC (show F9 Antibodies)) tissues and its mRNA expression decreased. Moreover, the hypermethylation of HOXD10 was associated with invasion of the primary tumor. Further data provide evidence that the epigenetic suppression of the HOXD10 gene may play a role in the tumorigenesis of PTC (show F9 Antibodies).

  2. Results show that HOXD10 is frequently methylated in human hepatocellular carcinoma (HCC (show FAM126A Antibodies)), and the expression of HOXD10 is regulated by promoter region methylation. HOXD10 suppresses HCC (show FAM126A Antibodies) cell growth both in vitro and in vivo. HOXD10 suppresses human HCC (show FAM126A Antibodies) by inhibiting ERK (show EPHB2 Antibodies) signaling.

  3. our data suggest that the loss of HoxD10 function is common and may thus result in a progressive phenotype in PCa (show FLVCR1 Antibodies). HoxD10 may function as a biomarker that differentiates patients with BCR (show BCR Antibodies) disease from the ones that are not after radical prostatectomy, implicating its potential as a therapeutic target.

  4. Knock down of the dickkopf (show DKK1 Antibodies) WNT (show WNT2 Antibodies) signaling pathway inhibitor 2 (DKK2 (show DKK2 Antibodies)) resulted in a significant suppression of HOXD10, HOXD11 (show HOXD11 Antibodies) and HOXD13 (show HOXD13 Antibodies) while over-expression of DKK2 (show DKK2 Antibodies) and stimulation with factors of the WNT (show WNT2 Antibodies) signaling pathway.

  5. By treating LECs with VEGF (show VEGFA Antibodies)-C156S and analyzing subsequent changes in gene expression, we identified several 'immediate early (show JUN Antibodies)' transcription factors that showed a rapid transient upregulation VEGFR-3 (show FLT4 Antibodies) stimulation. these results reveal an important and unanticipated role of HOXD10 in the regulation of VEGFR-3 (show FLT4 Antibodies) signaling in lymphatic endothelial cells, and in the control of lymphangiogenesis and permeability.

  6. Knockdown of HOXD10 in renal cells also resulted in increased resistance to colistin cytotoxicity.

  7. High expression of HOXD10 is associated with laryngeal squamous cell carcinoma.

  8. Low HOXD10 promotes migration and invasion in gastric cancer.

  9. These results suggested that HOXD10 may be a putative suppressor gene and can act as a prognostic marker and potentially a novel therapeutic target for cholangiocellular carcinoma.

  10. miR (show MLXIP Antibodies)-23a was upregulated in glioma. This overexpression promoted glioma cell invasion, probably by modulating MMP-14 (show MMP14 Antibodies) via directly inhibiting the expression of HOXD10.

Mouse (Murine) Homeobox D10 (HOXD10) interaction partners

  1. The organization and distribution of lumbar motor neurons was examined in the spinal cords of Hoxd10/Hoxa10 (show HOXA10 Antibodies) double mutant animals. Double mutant mice have decreased numbers of lumbar motor neurons in both the medial and lateral motor columns.

  2. show that the intracellular domain of Notch1 (show NOTCH1 Antibodies), transcription factor Ets (show ETV7 Antibodies)-1 (show ETS1 Antibodies), and homeo box D10 (HOXD10).pre B-cell leukemia transcription factor 1(PBX1b (show PBX1 Antibodies)).PREP1 activate the rat renin (show REN Antibodies) promoter cooperatively

  3. The three paralogous genes, Hoxa10 (show HOXA10 Antibodies), Hoxc10 (show HOXC10 Antibodies), and Hoxd10, are all expressed in the lumbar spinal cord and have distinct expression patterns

  4. Gli3 (show GLI3 Antibodies) mutant limbs are characterized by a severe polydactyly and associated ectopic anterior expression of 5'Hoxd genes.

  5. Hoxc10 (show HOXC10 Antibodies) and Hoxd10 play key roles in establishing lumbar motoneuron columnar, divisional and motor pool identity

HOXD10 Antigen Profile

Protein Summary

This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as 'rocker-bottom foot' deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.

Gene names and symbols associated with anti-Homeobox D10 (HOXD10) Antibodies

  • homeobox D10 (HOXD10) antibody
  • homeobox D10 (Hoxd10) antibody
  • homeo box D10 (Hoxd10) antibody
  • homeobox D10 L homeolog (hoxd10.L) antibody
  • homeobox D10 (hoxd10) antibody
  • homeobox D10a (hoxd10a) antibody
  • AI385591 antibody
  • AI874987 antibody
  • hox-4.4 antibody
  • Hox-4.5 antibody
  • Hox-5.3 antibody
  • HOX-D10 antibody
  • hox4 antibody
  • hox4d antibody
  • hox4e antibody
  • hoxd-10 antibody
  • hoxd10 antibody
  • HoxD10a antibody
  • Xhoxd10 antibody
  • z-82 antibody

Protein level used designations for anti-Homeobox D10 (HOXD10) Antibodies

homeo box 4D , homeo box D10 , homeobox protein Hox-4D , homeobox protein Hox-4E , homeobox protein Hox-D10 , homeobox protein Hox-4.5 , homeobox protein Hox-5.3 , homeobox D10 , homeobox protein, Hoxd10 , homeobox protein Hox-D10-like , homeobox gene D-10 , homeobox protein Hox-C10 , homeobox protein Hox-D10a , hox-C10 , Homeobox protein Hox-D10a , homeobox protein HoxD10a

GENE ID SPECIES
3236 Homo sapiens
15430 Mus musculus
303991 Rattus norvegicus
399032 Xenopus laevis
488415 Canis lupus familiaris
540251 Bos taurus
700318 Macaca mulatta
739607 Pan troglodytes
771246 Gallus gallus
100019168 Monodelphis domestica
100038085 Xenopus (Silurana) tropicalis
100066123 Equus caballus
100174239 Pongo abelii
100408283 Callithrix jacchus
100515344 Sus scrofa
100579168 Oryctolagus cuniculus
100586307 Nomascus leucogenys
30404 Danio rerio
101065273 Takifugu rubripes
100720292 Cavia porcellus
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