anti-Immunoglobulin (CD79A) Binding Protein 1 (IGBP1) Antibodies

The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Additionally we are shipping Immunoglobulin (CD79A) Binding Protein 1 Proteins (8) and Immunoglobulin (CD79A) Binding Protein 1 Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IGBP1 3476 P78318
IGBP1 58845 O08836
IGBP1 18518 Q61249
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Top anti-Immunoglobulin (CD79A) Binding Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 61 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated EIA, WB IGBP1 Antibody (Center) western blot analysis in HepG2 cell line lysates (35µg/lane).This demonstrates the IGBP1 antibody detected the IGBP1 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Human Mouse Un-conjugated FACS, IF HEK293T cells transfected with either RC200387 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-IGBP1 antibody (ABIN2453823), and then analyzed by flow cytometry. Anti-IGBP1 mouse monoclonal antibody (ABIN2453823) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IGBP1 (RC200387). 100 μL 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti CD79A/IGBP-1 Polyclonal Antibody, Unconjugated (ABIN727578) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat lung tissue labeled with Anti-IGBP1 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL 3 to 7 Days
$329.45
Details
Human Rabbit Un-conjugated WB Western blot analysis in HepG2 cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details
Human Mouse Un-conjugated WB Western Blot analysis of IGBP1 expression in transfected 293T cell line by IGBP1 MaxPab polyclonal antibody.Lane 1: IGBP1 transfected lysate(37.29 KDa).Lane 2: Non-transfected lysate. IGBP1 MaxPab polyclonal antibody. Western Blot analysis of IGBP1 expression in human pancreas. 50 μL 11 to 12 Days
$440.00
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL 14 to 21 Days
$428.45
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL 14 to 21 Days
$428.45
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL 14 to 21 Days
$428.45
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL 14 to 21 Days
$428.45
Details
Human Rabbit Cy5.5 IF (p)   100 μL 14 to 21 Days
$428.45
Details

Top referenced anti-Immunoglobulin (CD79A) Binding Protein 1 Antibodies

  1. Human Polyclonal IGBP1 Primary Antibody for IP, WB - ABIN151932 : LeNoue-Newton, Watkins, Zou, Germane, McCorvey, Wadzinski, Spiller: The E3 ubiquitin ligase- and protein phosphatase 2A (PP2A)-binding domains of the Alpha4 protein are both required for Alpha4 to inhibit PP2A degradation. in The Journal of biological chemistry 2011 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal IGBP1 Primary Antibody for IF (p), IHC (p) - ABIN727578 : Luo, Wei, Wang, Wang: Paternal bisphenol a diet changes prefrontal cortex proteome and provokes behavioral dysfunction in male offspring. in Chemosphere 2017 (PubMed)

  3. Human Polyclonal IGBP1 Primary Antibody for ICC, IF - ABIN4321453 : Lee, Kwon, Ghang, Lim, Kim, Hong, Lee, Yoo, Kim: Immunoglobulin Binding Protein 1 as a Potential Urine Biomarker in Patients with Lupus Nephritis. in International journal of molecular sciences 2019 (PubMed)

More Antibodies against Immunoglobulin (CD79A) Binding Protein 1 Interaction Partners

Human Immunoglobulin (CD79A) Binding Protein 1 (IGBP1) interaction partners

  1. Knockdown of Alpha4 preferentially impacts the expression of PP4c and PP6c compared to expression levels of PP2Ac.

  2. Data show that loss of epithelial membrane protein 2 (EMP2) is involved in sphingosylphosphorylcholine (SPC)-induced phosphorylation of keratin 8 (K8) via ubiquitination of protein phosphatase 2 (PP2A) through alpha4 phosphoprotein by caveolin-1 (cav-1).

  3. MID1 catalyzes the ubiquitination of protein phosphatase 2A and mutations within its Bbox1 domain disrupt polyubiquitination of alpha4 but not of PP2Ac in X-linked Opitz syndrome.

  4. alpha4 is an important regulatory molecule of apoptosis and Bcl-xL phosphorylation induced by BCR crosslinking.

  5. the alpha4 N-terminus binding to endogenous PP2Ac and PABP, and the C-terminus to EDD, is reported.

  6. A potential important role of alpha4 in control of cell migration and/or invasion via the regulation of E-cadherin expression in bladder urothelial carcinoma.

  7. The structure of alpha45 reveals two distinct surfaces, one that can interact with a negatively charged surface, which is present on PP2A, and one that interacts with the Bbox1 domain of MID1.

  8. alpha4 is highly expressed in carcinogen-transformed human cells and primary human cancers.

  9. both the C-terminal Mid1-binding domain and the PP2Ac-binding determinants are required for Alpha4-mediated protection of PP2Ac from polyubiquitination and degradation.

  10. IGBP-1 is expressed universally in advanced lung adenocarcinomas, and its overexpression is significantly related to outcome.

  11. Data show that in addition to PP2Ac, alpha4 interacts with EDD and PABP, suggesting its involvement in multiple steps in the mTOR pathway that leads to translation initiation and cell-cycle progression.

  12. Alpha 4, a regulatory subunit of PP2-type phosphatases and a key component of the rapamycin-sensitive signaling pathway, has been indentified as a strong interactor of both MID1 and MID2.

  13. alpha4 C-terminal deletion mutants at 222 (alpha4Delta222), 236 (alpha4Delta236) & 254 (alpha4Delta254) were expressed. alpha4Delta222 & alpha4Delta236 possess a higher content of alpha-helix, indicating that C-terminal region is less structured.

  14. a new role for mTOR and alpha4/PP2Ac in the control of STAT1 nuclear content, and the expression of interferon-gamma-sensitive genes involved in immunity and apoptosis.

Mouse (Murine) Immunoglobulin (CD79A) Binding Protein 1 (IGBP1) interaction partners

  1. Report the significance and altered activity of the type 2A protein phosphatase-alpha4 complex in healthy and hypertrophied myocardium.

  2. both the C-terminal Mid1-binding domain and the PP2Ac-binding determinants are required for Alpha4-mediated protection of PP2Ac from polyubiquitination and degradation.

  3. results show that alpha4, a noncatalytic subunit of protein phosphatase 2A, is required to repress apoptosis in murine cells

  4. alpha4 expression differentially increased or decreased phosphorylation of endogenous phosphoproteins, consistent with opposing effects on PP2A and PP6

  5. Alpha4 (Igbp1) plays a required role in regulating the assembly and maintenance of adaptive PP2A phosphatase complexes.

Immunoglobulin (CD79A) Binding Protein 1 (IGBP1) Antigen Profile

Protein Summary

The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways.

Gene names and symbols associated with IGBP1

  • immunoglobulin binding protein 1 (IGBP1) antibody
  • immunoglobulin binding protein 1 (Igbp1) antibody
  • immunoglobulin (CD79A) binding protein 1 (igbp1) antibody
  • immunoglobulin (CD79A) binding protein 1 (Igbp1) antibody
  • immunoglobulin (CD79A) binding protein 1 L homeolog (igbp1.L) antibody
  • immunoglobulin (CD79A) binding protein 1 (IGBP1) antibody
  • AI115586 antibody
  • AI662457 antibody
  • ALPHA-4 antibody
  • AW208785 antibody
  • C81413 antibody
  • fc70b08 antibody
  • fi33h08 antibody
  • ibp1 antibody
  • IGBP1 antibody
  • MGC83250 antibody
  • MGC147560 antibody
  • p52 antibody
  • Pc52 antibody
  • Tap42 antibody
  • wu:fc70b08 antibody
  • wu:fi33h08 antibody
  • zgc:55347 antibody

Protein level used designations for IGBP1

B cell signal transduction molecule alpha 4 , B-cell signal transduction molecule alpha 4 , CD79a-binding protein 1 , bA351K23.1 (immunoglobulin binding protein 1 (CD79A) ) , immunoglobulin-binding protein 1 , protein alpha-4 , protein phosphatase 2/4/6 regulatory subunit , protein phosphatase 2A, regulatory subunit alpha-4 , renal carcinoma antigen NY-REN-16 , alpha4 phosphoprotein , immunoglobulin binding protein 1 , alpha 4 , lymphocyte signal transduction molecule alpha 4 , phosphoprotein, component, 52 kDa , immunoglobulin (CD79A) binding protein 1

GENE ID SPECIES
3476 Homo sapiens
58845 Rattus norvegicus
406843 Danio rerio
480950 Canis lupus familiaris
18518 Mus musculus
414701 Xenopus laevis
694632 Macaca mulatta
779894 Xenopus (Silurana) tropicalis
100296883 Bos taurus
100154214 Sus scrofa
100733701 Cavia porcellus
768951 Gallus gallus
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