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anti-Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS) Antibodies

The protein encoded by IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Additionally we are shipping Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit Kits (21) and Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IGFALS 3483 P35858
IGFALS 16005 P70389
IGFALS 79438 P35859
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Top anti-Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit Antibodies at antibodies-online.com

Showing 10 out of 70 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Guinea Pig Rabbit Un-conjugated WB WB Suggested Anti-IGFALS Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-IGFALS Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of IGFALS Antibody (Center) (ABIN391690) in mouse spleen tissue, Jurkat cell line and mouse liver tissue lysates (35 µg/lane). IGFALS (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with IGFALS Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: IGFALS Antibody [NBP1-89117] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted) Immunocytochemistry/Immunofluorescence: IGFALS Antibody [NBP1-89117] - Staining of human cell line U-251 MG shows positivity in nucleus but not nucleoli. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis of extracts from COLO205 cells, using IGFALS antibody.The lane on the left is treated with the antigen-specific peptide. ABIN6275714 staining COLO205 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB Western Blot: IGFALS Antibody [NBP1-32874] - Sample (30 ug of whole cell lysate) A: H1299 B: Hela 7.5% SDS PAGE; antibody diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$727.83
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of IGFALS Antibody in mouse spleen tissue, Jurkat cell line and mouse liver tissue lysates (35ug/lane) Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with IGFALS Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details

Top referenced anti-Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit Antibodies

  1. Cow (Bovine) Polyclonal IGFALS Primary Antibody for ELISA - ABIN4223060 : Hosgood, Menashe, Shen, Yeager, Yuenger, Rajaraman, He, Chatterjee, Caporaso, Zhu, Chanock, Zheng, Lan: Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. in Carcinogenesis 2008 (PubMed)

More Antibodies against Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit Interaction Partners

Human Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS) interaction partners

  1. The aim of this study was to evaluate the potential pathogenicity of eleven IGFALS variants.

  2. Previously characterized disease-causing mutations in IGF2, IGF1R (show IGF1R Antibodies), IGF2R (show IGF2R Antibodies), or IGFALS all were found in the general population but with allele frequencies of <1:30,000.

  3. To the known phenotype of ACLSD (i.e. short stature, reduced serum levels of IGF-I and ALS, extremely low serum IGFBP-3 and disturbed ternary complex formation), the study adds reduced birth weight, head circumference and serum IGF-II.

  4. Mutations in the IGFALS and low expression level of IGFALS proteins lead to growth and development retardation. [Review]

  5. A novel homozygous mutation in IGFALS, c.380T>C (p.L127P), was identified in two siblings of a consanguineous family.

  6. Heterozygous IGFALS gene variants could be responsible for short stature in a subset of idiopathic short stature children with diminished levels of IGF-1, IGFBP-3 and ALS.

  7. These gene dosage effects demonstrate that one functional IGFALS allele is insufficient to maintain normal ALS levels, endocrine IGF-I (show IGF1 Antibodies) action, full growth potential, muscle size, and periosteal expansion.

  8. functional analysis supported a tumor-suppressive function for IGFALS in vitro.

  9. Heterozygous STAT5B mutations, with or without heterozygous IGFALS defects, may be associated with growth hormone insensitivity.

  10. low circulating IGF-I (show IGF1 Antibodies) levels due to Acid-Labile Subunit deficiency in adulthood are not associated with early development of atherosclerosis and impaired heart function.

Mouse (Murine) Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS) interaction partners

  1. the Igfals gene has a role in skeletal response of male mice to anabolic hormone therapy

  2. A modest reduction in post-natal growth in the null ALS mice and in the ALS-deficient patients was observed

Pig (Porcine) Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS) interaction partners

  1. The isolation and characterization of the IGFALS gene, including its expression profile and variations, are reported.

Cow (Bovine) Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS) interaction partners

  1. Polymorphisms in the IGFALS gene are associated with growth traits in beef cattle (Bos taurus) in China.

Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS) Antigen Profile

Protein Summary

The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with IGFALS

  • insulin like growth factor binding protein acid labile subunit (IGFALS) antibody
  • insulin like growth factor binding protein acid labile subunit L homeolog (igfals.L) antibody
  • insulin-like growth factor binding protein, acid labile subunit (Igfals) antibody
  • Albs antibody
  • Als antibody
  • mKIAA4111 antibody

Protein level used designations for IGFALS

insulin-like growth factor binding protein, acid labile subunit , insulin-like growth factor-binding protein complex acid labile subunit-like , insulin-like growth factor binding protein complex acid labile chain , insulin-like growth factor-binding protein complex acid labile subunit , insulin-like growth factor binding protein complex acid-labile subunit , insulin-like growth factor-binding protein complex acid labile chain , insulin-like growth factor binding protein, acid-labile subunit

GENE ID SPECIES
467869 Pan troglodytes
490069 Canis lupus familiaris
100101314 Xenopus laevis
100414686 Callithrix jacchus
3483 Homo sapiens
16005 Mus musculus
79438 Rattus norvegicus
397322 Sus scrofa
532494 Bos taurus
427649 Gallus gallus
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