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The protein encoded by IL13RA2 is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex.
Showing 10 out of 113 products:
Human Polyclonal IL13RA2 Primary Antibody for BR, CyTOF - ABIN5012923
Trieu, Wen, Skinnider, Bray, Li, Claudio, Masih-Khan, Zhu, Trudel, McCart, Mak, Stewart: Soluble interleukin-13Ralpha2 decoy receptor inhibits Hodgkin's lymphoma growth in vitro and in vivo. in Cancer research 2004
Show all 15 Pubmed References
Human Monoclonal IL13RA2 Primary Antibody for IHC (fro), FACS - ABIN1383686
Joshi, Plautz, Puri: Interleukin-13 receptor alpha chain: a novel tumor-associated transmembrane protein in primary explants of human malignant gliomas. in Cancer research 2000
Show all 8 Pubmed References
Human Monoclonal IL13RA2 Primary Antibody for RNAi, ELISA - ABIN561476
Zeis, Graumann, Reynolds, Schaeren-Wiemers: Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection. in Brain : a journal of neurology 2007
Human Polyclonal IL13RA2 Primary Antibody for FACS - ABIN4896504
Biancheri, Di Sabatino, Ammoscato, Facciotti, Caprioli, Curciarello, Hoque, Ghanbari, Joe-Njoku, Giuffrida, Rovedatti, Geginat, Corazza, MacDonald: Absence of a role for interleukin-13 in inflammatory bowel disease. in European journal of immunology 2014
This study shows interleukin-13 receptor alpha 2 expression could be a useful prognostic marker for selecting patients with luminal breast cancer likely to follow a clinically aggressive course despite receiving systemic therapy.
Transgenic expression of IL15 (show IL15 Antibodies) is an appealing strategy to enhance CAR T-cell effector function. We tested this approach in our IL13Ralpha2-positive glioma model in which limited IL13Ralpha2-CAR T-cell persistence results in recurrence of antigen-positive gliomas. T cells were genetically modified with retroviral vectors encoding IL13Ralpha2-CARs or IL15 (show IL15 Antibodies) (IL13Ralpha2-CAR.IL15 T cells).
cigarette smoke extracts activate the PKA, CREB (show CREB1 Antibodies), and IL-13Ralpha2 axis in lung endothelial cells.
High expression of IL-13Ra2 is significantly associated with the growth and metastasis of glioma cells via the Scr/PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) pathway.
A negative correlation between IL-13Ra2 and IL-13 (show IL13 Antibodies) was found during early infection of human schistosomiasis, suggesting an increase in cytokine in early fibrosis.
Data indicate single-chain antibody (scFv47) as a highly selective interleukin 13 receptor subunit alpha 2 (IL13Ralpha2) targeting agent.
IL13Ralpha2 knockdown and IL-13 (show IL13 Antibodies) treatment cooperatively upregulated the metastasis suppressor tumor protein 63 (TP63 (show TP63 Antibodies)) in a STAT6 (show STAT6 Antibodies)-dependent manner.
Expression of CXCR3 (show CXCR3 Antibodies) in fibroblasts is associated with the expression of IL-13Ralpha2.
Study presents evidence that PNR (show NR2E3 Antibodies) could promote ERalpha (show ESR1 Antibodies)-negative breast cancer metastasis through activation of IL-13Ralpha2-mediated signaling pathway.
Results suggest that the physical interaction between the cytoplasmic domains of IL-13Ralpha2 and IL-4Ralpha regulates IL-4 (show IL4 Antibodies) signaling through the IL-4Ralpha-IL-13Ralpha1 receptor complex.
Upon lipopolysaccharide stimulation, macrophage Raw 264.7 cells showed elevated IL-13R-alpha-2 expression via immunofluorescence staining and increased MRI (show C7ORF49 Antibodies) probe binding via built-in TAMRA fluorescence imaging. for the first time, IL-13R-alpha-2 was investigated as a unique biomarker in the context of osteomyelitis.
overexpression of IL-13Ra2 inhibits the IL-13 (show IL13 Antibodies) induction of fibrotic markers in vitro and inhibits bleomycin-induced pulmonary fibrosis.
IL-13 (show IL13 Antibodies) contributes to the development of pulmonary hypertension via an IL-13receptor alpha2-arginase 2 (show ARG2 Antibodies)-dependent pathway.
Colitis and intestinal inflammation in IL10 (show IL10 Antibodies)(-/-) mice results from IL-13Ralpha2-mediated attenuation of IL-13 (show IL13 Antibodies) activity.
These results are consistent with a phenotype of enhanced interleukin-13 (IL-13 (show IL13 Antibodies))responsiveness and demonstrate a role for endogenous IL-13 (show IL13 Antibodies) and IL-13 (show IL13 Antibodies) alpha2 receptor in regulating immune responses in wild-type mice.
IL-13 (show IL13 Antibodies) receptor alpha2
by suppressing IFN-gamma (show IFNG Antibodies) and up-regulating the decoy IL-13 (show IL13 Antibodies) receptor, P-selectin (show SELP Antibodies) dramatically inhibits the pathologic tissue remodeling that results from chronic type 2 cytokine-mediated hepatic inflammation
TGF-beta1 (show TGFB1 Antibodies) production and fibrosis require IL-13 (show IL13 Antibodies) signaling through the IL-13alpha2 receptor
IL-10 (show IL10 Antibodies) and IL-13Ralpha2 are both required to control chronic Th2-driven pathological responses.
The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.
interleukin-13 receptor alpha 2
, interleukin-13 receptor subunit alpha-2
, IL-13 receptor alpha 2
, interleukin 13 receptor, alpha 2
, interleukin-13 receptor subunit alpha-2-like
, IL-13 receptor subunit alpha-2
, IL-13R subunit alpha-2
, cancer/testis antigen 19
, interleukin 13 binding protein
, interleukin 13 receptor alpha 2 chain
, interleukin-13-binding protein
, interleukin 13 receptor alpha chain 2