anti-Interleukin 17 Receptor A (IL17RA) Antibodies

Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. Additionally we are shipping IL17RA Proteins (41) and IL17RA Kits (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IL17RA 23765 Q96F46
IL17RA 312679  
IL17RA 16172 Q60943
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Top anti-IL17RA Antibodies at

Showing 10 out of 140 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of IL17RA using anti-IL17RA antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: human Hela whole cell lysate, Lane 2: human HepG2 whole cell lysate, Lane 3: human MCF-7 whole cell lysate.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-IL17RA antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for IL17RA at approximately 160KD. The expected band size for IL17RA is at 96KD. 100 μg 4 to 6 Days
Rat Goat Un-conjugated ELISA, WB   100 μg 6 to 7 Days
Human Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Human BXPC3 cell lysate; Primary Ab: 1.5µg/ml Rabbit Anti-Human IL17RA Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg 13 to 16 Days
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Mouse Pancreas Tissue. 100 μg 13 to 16 Days
Human Mouse Un-conjugated WB 100 μL 14 to 16 Days
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis of extracts from LOVO cells, using IL17RAantibody.The lane on the left is treated with the antigen-specific peptide. ABIN6274673 staining LOVO by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. 100 μL 11 to 12 Days
Mouse Goat Un-conjugated EIA, WB   0.1 mg 4 to 8 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse lymphoma labeled with Anti-IL-17RA/CD217 Polyclonal Antibody, Unconjugated (ABIN747908) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
Human Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg 13 to 16 Days
Mouse Rabbit Un-conjugated WB Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the detected the Mouse Il17ra protein (arrow). 400 μL 2 to 3 Days

Top referenced anti-IL17RA Antibodies

  1. Human Monoclonal IL17RA Primary Antibody for CyTOF, FACS - ABIN4900233 : Numasaki, Watanabe, Suzuki, Takahashi, Nakamura, McAllister, Hishinuma, Goto, Lotze, Kolls, Sasaki: IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)
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  2. Mouse (Murine) Polyclonal IL17RA Primary Antibody for CyTOF, FACS - ABIN4900540 : Subbarayal, Chauhan, Di Zazzo, Dana: IL-17 Augments B Cell Activation in Ocular Surface Autoimmunity. in Journal of immunology (Baltimore, Md. : 1950) 2016 (PubMed)
    Show all 8 Pubmed References

  3. Human Polyclonal IL17RA Primary Antibody for CyTOF, FACS - ABIN4900235 : Cattaruzza, Gloghini, Olivo, Di Francia, Lorenzon, De Filippi, Carbone, Colombatti, Pinto, Aldinucci et al.: Functional coexpression of Interleukin (IL)-7 and its receptor (IL-7R) on Hodgkin and Reed-Sternberg cells: Involvement of IL-7 in tumor cell growth and microenvironmental interactions of Hodgkin's ... in International journal of cancer 2009 (PubMed)
    Show all 6 Pubmed References

  4. Human Monoclonal IL17RA Primary Antibody for FACS - ABIN4897412 : Ahn, Edwards, Singh, Young, Lessey, Tayade: IL-17A Contributes to the Pathogenesis of Endometriosis by Triggering Proinflammatory Cytokines and Angiogenic Growth Factors. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Show all 4 Pubmed References

  5. Mouse (Murine) Monoclonal IL17RA Primary Antibody for CyTOF, FACS - ABIN4900207 : Ippagunta, Gangwar, Finkelstein, Vogel, Pelletier, Gingras, Redecke, Häcker: Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function. in Proceedings of the National Academy of Sciences of the United States of America 2016 (PubMed)
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  6. Human Monoclonal IL17RA Primary Antibody for IHC, IHC (p) - ABIN4324586 : Sebastian, Kannan, Norazmi, Nurul: Interleukin-17A promotes osteogenic differentiation by increasing OPG/RANKL ratio in stem cells from human exfoliated deciduous teeth (SHED). in Journal of tissue engineering and regenerative medicine 2018 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal IL17RA Primary Antibody for FACS - ABIN4897414 : Lotti, Jarrar, Pai, Hitomi, Lathia, Mace, Gantt, Sukhdeo, DeVecchio, Vasanji, Leahy, Hjelmeland, Kalady, Rich: Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A. in The Journal of experimental medicine 2013 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal IL17RA Primary Antibody for IF (p), IHC (p) - ABIN747908 : Zhang, Zhou, Chen, Yang, Shi: Identification of hub genes and pathways associated with bladder cancer based on co-expression network analysis. in Oncology letters 2017 (PubMed)

  9. Human Polyclonal IL17RA Primary Antibody for WB - ABIN6681923 : Ganesan, Rasool: Interleukin 17 regulates SHP-2 and IL-17RA/STAT-3 dependent Cyr61, IL-23 and GM-CSF expression and RANKL mediated osteoclastogenesis by fibroblast-like synoviocytes in rheumatoid arthritis. in Molecular immunology 2017 (PubMed)

More Antibodies against IL17RA Interaction Partners

Human Interleukin 17 Receptor A (IL17RA) interaction partners

  1. We identify regions R1 and R2 as novel LRI enhancers for IL17RA. In line with these findings, two SNPs within 5-8 kb of R1 are associated with psoriasis in our novel discovery cohort.

  2. The SNP rs4819554 in the promoter region of IL17RA significantly influences the response to anti-TNF drugs at week 12.

  3. Combination of polymorphisms in the NOD2, IL17RA, EPHA2 and KALRN genes could play a significant role in the development of sarcoidosis by maintaining a chronic pro-inflammatory status in macrophages

  4. The data connect increased interleukin (IL)-17A/IL-17RA signaling in autism spectrum disorder patients with enhanced oxidative inflammation in monocytes.

  5. IL-17RA is essential for mucocutaneous immunity to Candida and Staphylococcus, but otherwise largely redundant

  6. Here, we discuss the latest discoveries on the role of the IL-17A/IL-17RA axis in driving host pulmonary defence and immunopathology.

  7. High IL-17RA expression is associated with prostate cancer.

  8. Expression of these mediators was confirmed in end-stage COPD. Thus, accumulation of mast cells in COPD may contribute to vascular remodeling.

  9. cyanidin specifically recognizes an IL-17A binding site in the IL-17A receptor subunit (IL-17RA) and inhibits the IL-17A/IL-17RA interaction.

  10. SNP rs4819554 in promoter is associated with functional severity of ankylosing spondylitis

  11. It has been shown that IL-17 can be produced by enteroendocrine chromogranin A-positive cells as well as by goblet cells in the human colon.

  12. Results suggest that IL-17-IL-17R interaction in GSCs induces an autocrine/paracrine cytokine feedback loop, which may provide an important signaling component for maintenance/self-renewal of GSCs.

  13. High IL-17RA expression is associated with Intrahepatic Cholangiocarcinoma.

  14. Identified the IL17RA rs4819554 SNP as a risk factor for psoriasis.

  15. IL-17 receptor A and adenosine deaminase 2 deficiency due to deletion mutations was found in siblings with chronic mucocutaneous candidiasis and chronic systemic inflammation.

  16. In vitro, CSE stimulation significantly increased IL-17F and IL-17R in 16HBE (2.5%) and A549 (5%) while IL-17A and IL-17F in PBMC (10%). IL-17A and CSE stimulation, rather than CSE or rhIL-17A alone, increased proliferation in 16HBE and apoptosis in A549

  17. The data indicate that the genetic variants of rs2275913 in IL-17A, rs763780 in IL-17F, and rs4819554 in IL-17RA may not play a role in the pathogenesis of preeclampsia in Chinese Han women.

  18. IL17F and IL17RA polymorphisms modulate susceptibility to cerebral malaria(CM) and provide evidence that IL-17F protects against CM.

  19. Increased expression of IL-17RA plays an important role in gastric cancer progression, migration and prognosis.

  20. Both genetic variants of IL-17R (rs882643 and rs2241049) were associated with PGD. This confirms a genetic predisposition toward PGD and suggests a role of IL-17 in driving neutrophilia in PGD.

Mouse (Murine) Interleukin 17 Receptor A (IL17RA) interaction partners

  1. our results provide evidence for a novel IL-17RA-mediated mechanism that potentiates immunity to intracellular pathogens such as T. cruzi by improving adaptive CD8+ T cell responses.

  2. these findings indicate that RKIP functions as an essential modulator of the IL-17R-Act1 axis in IL-17R signaling, which promotes IL-17-induced inflammation and autoimmune neuroinflammation

  3. Study shows that miR-215 regulates the Act1/IL-17RA pathway and represses the expression of Act1 protein in oxygen glucose deprivation/reperfusion-treated N2a cells and an middle cerebral artery occlusion mouse model of ischemic stroke.

  4. study provides insight regarding a novel antiviral role for IL-17A in the genital tract, in which IL-17A improves mucosal vaccination efficacy by mediating efficient Th1 cell immunity

  5. This study describes a previously unappreciated protective role for IL-17RA signaling in regulation of the skin barrier and maintenance of skin immune homeostasis.

  6. These data show that IL-17R signaling in the lung epithelium plays a critical role in establishing chemokine gradients that are essential for mucosal immunity against pulmonary bacterial pathogens.

  7. Thus, oral epithelial cells dominantly control IL-17R-dependent responses to oropharyngeal candidiasis through regulation of BD3 expression.

  8. this study showsthat the nature of the protective memory response depends closely on the route of infection and highlights the role of IFN-gamma-and IL-17RA-mediated responses in the control of mucosal infection by Brucella

  9. IL-17RA contributes to experimental glomerulonephritis, with IL-17RA expression on both leukocytes and stromal cells being required for the full expression of nephritogenic humoral immunity.

  10. genetic deletion results in earlier onset of experimental autoimmune encephalomyelitis and worsened disease severity

  11. IL-17RA in non hematopoietic cells regulates recruitment of neutrophils to the lung during the adaptive phase of the immune response.

  12. Bronchial epithelial TLR2/IL17R signaling crosstalk is necessary for lung IL17 homeostasis and is compromised by morphine.

  13. IL-17 signaling through IL-17RA is an important driver of lung inflammation and airway hyperresponsiveness.

  14. results suggest that the p38alpha-MKP-1 signaling axis links IL-17R signaling in tissue-resident cells to autoimmune inflammation dependent on infiltrating T(H)17 cells.

  15. There were no significant differences in clinical scores and numbers of infiltrating eosinophils among IL-25KO, TSLPR KO, and wild-type mice.

  16. promotes colorectal tumorigenesis in transformed enterocytes

  17. IL-17RA signaling is critical for the development of renal pathology in autoimmune glomerulonephritis.IL-17 enhanced the production of proinflammatory cytokines and chemokines from tubular epithelial cells.

  18. Il17ra appears to be a novel modulator of monocyte phenotype and possible therapeutic target in renal fibrosis

  19. IL-17 expression is higher in C57BL/6 versus BALB/c cornea after infection and that the latter group has more MerTK+ cells.

  20. It was concluded that TLR signaling can directly stimulate the expression of IL-17RA, but not IL-17RC, in neuroglial cells, which functionally respond to IL-17A by secreting chemokines, and accelerating CD4 cell migration.

IL17RA Antigen Profile

Protein Summary

Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor\; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.

Gene names and symbols associated with IL17RA

  • interleukin 17 receptor A (IL17RA) antibody
  • interleukin 17 receptor A (Il17ra) antibody
  • AW538159 antibody
  • CANDF5 antibody
  • CD217 antibody
  • Cdw217 antibody
  • hIL-17R antibody
  • IL-17RA antibody
  • Il17r antibody
  • VDw217 antibody

Protein level used designations for IL17RA

IL-17 receptor A , interleukin-17 receptor A , IL-17RA

418158 Gallus gallus
23765 Homo sapiens
312679 Rattus norvegicus
16172 Mus musculus
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