anti-IL18BP Antibodies

Protein Summary

The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with IL18BP

• interleukin 18 binding protein (IL18BP) antibody
• interleukin 18 binding protein (Il18bp) antibody

• Igifbp antibody
• IL-18BP antibody
• IL18BP antibody
• IL18BPa antibody
• MC54L antibody

Protein level used designations for IL18BP

interleukin 18 binding protein , interferon gamma inducing factor binding protein , interferon gamma-inducing factor-binding protein , interleukin-18-binding protein , IL-18BP , MC51L-53L-54L homolog gene product , tadekinig-alfa , interleukin-18 binding protein