anti-Interleukin 18 Receptor 1 (IL18R1) Antibodies

The protein encoded by IL18R1 is a cytokine receptor that belongs to the interleukin 1 receptor family. Additionally we are shipping IL18R1 Proteins (28) and IL18R1 Kits (16) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IL18R1 8809 Q13478
IL18R1 16182 Q61098
IL18R1 301365  
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Top anti-IL18R1 Antibodies at antibodies-online.com

Showing 10 out of 161 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-IL18R1 Antibody Titration:  0.2-1 ug/ml  Positive Control:  PANC1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated CyTOF, FACS, ICC, IHC, Neut IL-18 R alpha/IL-1 R5 in Human PBMCs. IL-18 R alpha/IL-1 R5 was detected in immersion fixed human peripheral blood mononuclear cells (PBMCs) using 10 ug/mL Mouse Anti-Human IL-18 R alpha/IL-1 R5 Mono-clonal Antibody. IFN-gamma Secretion Induced by IL-18/IL-1F4 and Neutrali-zation by IL-18 R alpha/IL-1 R5 Antibody. In the presence of Recombinant Human TNF-alpha (20 ng/mL 100 μg Log in to see 8 to 9 Days
$329.96
Details
Human Goat Un-conjugated CyTOF, FACS, IHC, Neut, WB IFN-gamma Secretion Induced by IL-18/IL-1F4 and Neutralization by Human IL-18 R alpha/IL-1 R5 Antibody. Recombinant Human IL-18/IL-1F4 stimulates IFN-gamma secretion in the KG-1 human acute myelogenous leukemia cell line, in a dose-dependent manner (orange line), as measured by the Human IFN-gamma Quantikine ELISA Kit. The ND50 is typically 0.1-0.4 ug/mL. IL-18 R alpha/IL-1 R5 in Human Skin. IL-18 R alpha/IL-1 R5 was detected in immersion fixed frozen sections of human skin using Goat Anti-Human IL-18 R alpha/IL-1 R5 Antigen Affinity-purified Polyclonal Antibody. Specific labeling was localized to the plasma membrane of keratinocytes. 100 μg Log in to see 8 to 9 Days
$435.05
Details
Human Mouse Un-conjugated FACS 0.1 mg Log in to see 6 to 8 Days
$368.50
Details
Human Mouse PE FACS Detection of IL-18 R alpha/IL-1 R5 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) treated with 10 ng/mL Recombinant Human IL-2. 100 Tests Log in to see 8 to 9 Days
$342.39
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Mouse Cerebrum lysate; Primary Ab: 1.5µg/ml Rabbit Anti-Mouse IL18R1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Log in to see 15 to 18 Days
$342.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Mouse Stomach lysate; Primary Ab: 2µg/ml Rabbit Anti-Mouse IL18R1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Log in to see 13 to 16 Days
$342.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB Western blot analysis of extracts of A549 , using IL18R1antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6277318 staining Hela by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 16 Days
$366.77
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details

Top referenced anti-IL18R1 Antibodies

  1. Human Monoclonal IL18R1 Primary Antibody for CyTOF, FACS - ABIN4899497 : Tucci, Quatraro, Lombardi, Pellegrino, Dammacco, Silvestris: Glomerular accumulation of plasmacytoid dendritic cells in active lupus nephritis: role of interleukin-18. in Arthritis and rheumatism 2008 (PubMed)
    Show all 8 Pubmed References

  2. Human Monoclonal IL18R1 Primary Antibody for FACS - ABIN4896210 : Wu, Sakorafas, Miller, McCarthy, Scesney, Dixon, Ghayur: IL-18 receptor beta-induced changes in the presentation of IL-18 binding sites affect ligand binding and signal transduction. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 5 Pubmed References

  3. Human Polyclonal IL18R1 Primary Antibody for CyTOF, FACS - ABIN4899499 : Dusseaux, Martin, Serriari, Péguillet, Premel, Louis, Milder, Le Bourhis, Soudais, Treiner, Lantz: Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells. in Blood 2011 (PubMed)
    Show all 5 Pubmed References

  4. Human Monoclonal IL18R1 Primary Antibody for FACS - ABIN1383920 : Vermot-Desroches, Subiger, Guenot, Sergent, Bonnin, Wijdenes: Monoclonal antibodies specific for the IL-18 receptor. in Cellular immunology 2005 (PubMed)

More Antibodies against IL18R1 Interaction Partners

Cow (Bovine) Interleukin 18 Receptor 1 (IL18R1) interaction partners

  1. These results suggest that BAPC-1 is a stem/progenitor cell line and modulates the immuno-endocrine function of the anterior pituitary cells through its production of interleukin-18 and the IL-18 receptor.

Human Interleukin 18 Receptor 1 (IL18R1) interaction partners

  1. asthma is very likely to be determined by balance of IL-18/IL-18BP/IL-18R expression in inflammatory cells.

  2. IL-18, IL-18R and IL-18BP expression in eosinophil are involved in the inflammatory reaction of asthma.

  3. IL18R1 rs1035130 may be associated with schizophrenia.

  4. some SNPs of ST2-IL18R1-IL18RAP gene cluster might increase the risk of susceptibility of Graves' disease (GD) and Hashimoto's thyroiditis (HT) in Chinese Han population.

  5. IL-18 and IL-18R polymorphisms may contribute to the development and lymph node metastasis of PTC.

  6. strong evidence that IL-18 and IL18Ralpha have important functions in the pathogenesis of allergic asthma

  7. Human memory IL-18Ralpha and DR3 CD4+ T cells may contribute to antigen-independent innate responses at barrier surfaces.

  8. PDGFB and IL18R1 represent plausible candidates for studying the pathophysiology of these disorders in the context of TLR4 activation

  9. The architecture of the IL-18 receptor second domain (D2) is unique among the other IL-1R family members, which presumably distinguishes them from the IL-1 receptors that exhibit a more promiscuous ligand recognition mode.

  10. polymorphisms in the interleukin 18 receptor 1 gene and tuberculosis susceptibility among Chinese

  11. IL-37 requires the receptors IL-18Ralpha and IL-1R8 to carry out its multifaceted anti-inflammatory program upon innate signal transduction.

  12. There was no association between the rs917997 in IL18R gene and rs187238 in IL18 gene polymorphisms and risk for non-Hodgkin's malignant lymphomas in Novosibirsk population.

  13. IL-18, IL-18BP, and IL-18R may have roles in the pathogenesis of epithelial ovarian carcinoma

  14. IL-18R downregulates IFN-alpha production by activation-induced splicing of IL-18Ralpha into 2 isoforms: the full-length receptor (IL-18Ralpha1) and a novel, truncated variant (IL-18Ralpha2), a competitive molecular decoy inhibiting canonical IL-18Ralpha1/IL-18Rbeta signaling.

  15. structural basis for the specific recognition of IL-18 by its alpha receptor

  16. results demonstrate clear functional consequences of the rs917997 risk polymorphism; this polymorphism leads to a loss-of-function through decreased IL-18RAP, IL-18R1, and IL-1R1 protein expression, which impairs autocrine IL-18 and IL-1 signaling

  17. increased levels of soluble IL-18Ralpha complex in serum may also exert an antagonistic effect in vivo and play an important role in the inflammatory process in allergic asthma.

  18. Association between single nucleotide polymorphisms in the IL18R1, IL18 and interferon-gamma genes and smallpox vaccine induced adaptive immunity.

  19. Our study reveals the important role of IL12/IL18-mediated transcriptional regulation of IFN-gamma production in leprosy.

  20. Genetic variation in the promoter region of IL18, but not IL18R1, may be associated with knee osteoarthritis.

Mouse (Murine) Interleukin 18 Receptor 1 (IL18R1) interaction partners

  1. asthma is very likely to be determined by balance of IL-18/IL-18BP/IL-18R expression in inflammatory cells.

  2. IL-1R signaling licenses effector cytokine production by memory CD4 T cells

  3. IL-18R-immunoreactive neurons were present in layers II, III and VI of the retrosplenial cortex in 2-week-old mice, whereas they were sparsely observed in only layer III in 3-week-old mice. No IL-18R-ir neurons were present in 4- and 5-week-old mice. In older than 6-week-old mice, many IL-18R-ir neurons were present in layers V and VI.

  4. IL-18Ralpha-mediated signaling pathway plays critical role in CD4+ T cells and antigen-presenting cells response in LPS-induced acute kidney injury.

  5. These findings establish the T-cell intrinsic IL-18R/MyD88 pathway as a crucial element for induction of cognate Th1 responses against an important human pathogen.

  6. These observations suggest that IL-18 exerts direct effects upon the GnRH neuron via IL-18Ralpha and acts on GnRH neurons through an autocrine or paracrine pathway.

  7. Despite these findings however, IL-18Ralpha-deficient CD4(+) T cells induced comparable intestinal pathology to WT CD4(+) T cells. These findings suggest that IL-18-dependent cytokine induced activation of CD4(+) T cells is not critical for the development of T-cell-mediated colitis.

  8. strong evidence that IL-18 and IL18Ralpha have important functions in the pathogenesis of allergic asthma

  9. IL-37 requires IL-18Ralpha and SIGIRR/IL-1R8 to diminish allergic airway inflammation in mice

  10. This study identifies NCC as an IL18-binding protein that collaborates with IL18r in cell signaling, inflammatory molecule expression, and experimental atherogenesis.

  11. IL-37 requires the receptors IL-18Ralpha and IL-1R8 to carry out its multifaceted anti-inflammatory program upon innate signal transduction.

  12. data reveal that IL-18Ralpha has an anti-inflammatory effect in IRI-induced AKI. Above all, IL-18 enhanced the inflammatory mechanisms and the apoptosis of TECs through the Fas/FasL pathway by blocking IL-18Ralpha

  13. compared IL-18Ralpha knockout with wild-type mice in cisplatin-induced acute kidney injury and found deteriorated kidney function, tubular damage, and increased accumulation of leukocytes

  14. The presence or absence of IL-18 receptor alpha signals governs pathogenic versus protective immunity in a model of Ehrlichia-induced immunopathology.

  15. We identified low activity and high anxiety-like behaviors in Il18r1(-/-) mice, whereas Il18(-/-) mice displayed little anxiety-like behavior.

  16. These data suggest a role for IL-1F family members in psoriasis.

  17. the IL-1R and IL-18R/MyD88 pathways are required in distinctly different cells during the sensitization phase of contact hypersensitivity

  18. review of structure, function and tissue distribution of IL-18R [review]

  19. IL-18R alpha and IL-17-producing T helper cells are required for autoimmune central nervous system inflammation.

  20. IL-18Ralpha gene expression is regulated by estrogen and progesterone and that the uterine IL-18 system is involved in the regulation of uterine functions in a paracrine manner

IL18R1 Antigen Profile

Protein Summary

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q.

Gene names and symbols associated with IL18R1

  • interleukin 18 receptor 1 (IL18R1) antibody
  • interleukin 18 receptor 1 (Il18r1) antibody
  • CD218a antibody
  • CDw218a antibody
  • IL-1Rrp antibody
  • IL-18Ra antibody
  • Il1rrp antibody
  • IL18R1 antibody
  • IL18RA antibody
  • Il18ralpha antibody

Protein level used designations for IL18R1

IL-18 receptor alpha , interleukin-18 receptor 1 , interleukin 18 receptor 1 , interleukin-18 receptor 1-like , CD218 antigen-like family member A , IL-18R-1 , IL-18R1 , IL1 receptor-related protein , IL1R-rp , cytokine receptor , IL-1Rrp , interleukin 1 receptor related protein

GENE ID SPECIES
407221 Bos taurus
418717 Gallus gallus
459463 Pan troglodytes
493938 Felis catus
611438 Canis lupus familiaris
100303768 Oryctolagus cuniculus
100476694 Ailuropoda melanoleuca
8809 Homo sapiens
16182 Mus musculus
301365 Rattus norvegicus
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