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May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. Additionally we are shipping IL26 Kits (19) and IL26 Proteins (3) and many more products for this protein.
Showing 10 out of 64 products:
Human Monoclonal IL26 Primary Antibody for CyTOF, FACS - ABIN4899643
Ohnuma, Hatano, Aune, Otsuka, Iwata, Dang, Yamada, Morimoto: Regulation of pulmonary graft-versus-host disease by IL-26+CD26+CD4 T lymphocytes. in Journal of immunology (Baltimore, Md. : 1950) 2015
Human Monoclonal IL26 Primary Antibody for FACS - ABIN4896416
Anuradha, George, Hanna, Kumaran, Chandrasekaran, Nutman, Babu: Expansion of parasite-specific CD4+ and CD8+ T cells expressing IL-10 superfamily cytokine members and their regulation in human lymphatic filariasis. in PLoS neglected tropical diseases 2014
IL-26 levels are higher in synovial fluid compared to plasma in spondyloarthritis. IL-26 was identified in axial facet joints of spondyloarthritis patients. Myofibroblasts from the spondyloarthritis synovium produce large amounts of IL-26. IL-26 induces bone mineralization in human osteoblasts.
this study shows that IL-26 is a unique cationic protein more similar to a soluble pattern recognition receptor than to conventional cytokines
this study shows that single nucleotide polymorphism near IL-26 gene is associated with familial vitiligo (show MITF Antibodies) and existence of halo nevi in Estonian patients
Our study indicates that IL-26 is a potential biomarker of disease severity in pediatric asthma without signs of Th2-mediated inflammation.
IL-26 is emerging as a potentially important player in host defense and may also be a pathogenic factor in the chronic inflammatory disorders of humans. [Review]
The negative influence of IL-26 on the anti-mycobacterial activity and its constitutive presence in both serum and monocyte supernatants prompt a proposal that IL26 as a candidate gene for tuberculosis susceptibility.
IL-26 differentially modulates the infection by different enveloped viruses.
Elevated levels of IL-26 in human gastric cancer promote proliferation and survival by modulating STAT1 (show STAT1 Antibodies)/STAT3 (show STAT3 Antibodies) signaling.
IL-26 appears as a novel proinflammatory cytokine, located upstream of the proinflammatory cascade, that may constitute a promising target to treat rheumatoid arthritis and chronic inflammatory disorders.
Identify a second enhancer element positioned between IL26 and IFNG required for both IL26 and IFNG expression. One function of this enhancer is to facilitate recruitment of RNA polymerase II to promoters of both genes.
Expression analysis of IL-22 (show IL22 Antibodies), IL-26 and two IFN-gamma (show IFNG Antibodies) genes suggests an active role of these genes in immune responses in fish.
May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.
, interleukin 26