anti-Interleukin 27 (IL27) Antibodies

The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. Additionally we are shipping IL27 Kits (54) and IL27 Proteins (26) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IL27 246778 Q8NEV9
IL27 365368  
IL27 246779 Q8K3I6
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Top anti-IL27 Antibodies at antibodies-online.com

Showing 10 out of 164 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Biotin WB Western Blot of Biotin Conjugated Rabbit anti-IL-27/p28 antibody. Lane 1: Mouse IL-27/p28. Lane 2: None. Load: 50 ng per lane. Primary antibody: None. Secondary antibody: Biotin rabbit secondary antibody at 1:1,000 for 60 min at RT. Block: ABIN925618 for 30 min at RT. Predicted/Observed size: 24 kDa, 24 kDa for Mouse IL-27/p28. Other band(s): None. 100 μg Log in to see 5 to 7 Days
$583.50
Details
Mouse Rat Un-conjugated WB Anti-IL-27/p28 antibody in western blot shows detection of recombinant mouse IL-27/p28. Recombinant protein (0.1 µg) was loaded on to an SDS-PAGE gel, and after separation, transferred to nitrocellulose. The expected band is approximately 26 kDa in size. The membrane was blocked with 1% BSA in TBST for 30 min at RT, followed by incubation with  Anti-IL-27/p28 antibody diluted 1:1,000 in 1% BSA in TBST overnight at 4°C. After washes, the blot was reacted with secondary antibody HRP Goat anti-Rabbit IgG antibody diluted 1:40,000 in blocking buffer  for 30 min at RT. Data was collected using Bio-Rad 4000 MP imaging system. 100 μg Log in to see 5 to 7 Days
$583.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB 50 μg Log in to see 11 to 14 Days
$727.83
Details
Mouse Rabbit Un-conjugated WB Detection of recombinant IL27/p28 protein by  anti-Mouse IL-27/p28 antibody. Recombinant mouse IL27/p28 was loaded on to an SDS-PAGE gel at 0.25 µg and after separation, transferred to nitrocellulose. The membrane was blocked with 1% BSA in TBST for 30 min at RT, followed by incubation with primary antibody diluted 1:1,000 in 1% BSA in TBST overnight at 4°C. After washes, the blot was reacted with secondary antibody HRP Goat anti-Rabbit IgG antibody diluted 1:40,000 in blocking buffer  for 30 min at RT. Data was collected using Bio-Rad 4000 MP imaging system. 100 μg Log in to see 5 to 7 Days
$583.50
Details
Mouse Rat Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
$639.83
Details
Mouse Rabbit Un-conjugated WB IL27 Antibody (Center) (ABIN658144) western blot analysis in mouse liver tissue lysates (35 µg/lane). This demonstrates the IL27 antibody detected the IL27 protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of Mouse lung tissue lysate, using IL27 Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6277619 at 1/100 staining Human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Log in to see 11 to 12 Days
$390.77
Details
Mouse Rabbit HRP WB Recombinant mouse IL27/p28 was loaded at 0.25 µg. The blot was blocked with 1% BSA in TBST for 30 min at RT. Blot was incubated with HRP rabbit anti-Mouse IL-27/p28 in 1% BSA/TBST at 1:5,000 for 30 min at RT. Data was collected using Bio-Rad 4000 MP. 100 μg Log in to see 5 to 7 Days
$583.50
Details

Top referenced anti-IL27 Antibodies

  1. Mouse (Murine) Monoclonal IL27 Primary Antibody for ICS, Neut - ABIN2689756 : Hall, Silver, Hunter: The immunobiology of IL-27. in Advances in immunology 2012 (PubMed)
    Show all 7 Pubmed References

  2. Mouse (Murine) Monoclonal IL27 Primary Antibody for FACS - ABIN4896017 : Yoshida, Yoshimi, Yoshii, Kim, Dey, Xiong, Munasinghe, Yazawa, ODonovan, Maximova, Sharma, Zhu, Wang, Morse, Ozato: The transcription factor IRF8 activates integrin-mediated TGF-β signaling and promotes neuroinflammation. in Immunity 2014 (PubMed)

  3. Mouse (Murine) Polyclonal IL27 Primary Antibody for WB - ABIN1043831 : Pflanz, Timans, Cheung, Rosales, Kanzler, Gilbert, Hibbert, Churakova, Travis, Vaisberg, Blumenschein, Mattson, Wagner, To, Zurawski, McClanahan, Gorman, Bazan, de Waal Malefyt, Rennick, Kastelein: IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. in Immunity 2002 (PubMed)

  4. Mouse (Murine) Monoclonal IL27 Primary Antibody for WB - ABIN1043835 : Murugaiyan, Mittal, Weiner: Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-gamma limits IL-17-mediated autoimmune inflammation. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)

  5. Human Monoclonal IL27 Primary Antibody for CyTOF, FACS - ABIN4900122 : Seyerl, Kirchberger, Majdic, Seipelt, Jindra, Schrauf, Stöckl: Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC. in European journal of immunology 2010 (PubMed)

More Antibodies against IL27 Interaction Partners

Human Interleukin 27 (IL27) interaction partners

  1. our results showed that SNP rs153109 displayed significant associations with dilated cardiomyopathy in Chinese Han population, whereas no differences in genotype or allele frequencies were found between dilated cardiomyopathy patients and controls at SNP rs17855750.

  2. Human Immunodeficiency virus type-1 myeloid derived suppressor cells inhibit cytomegalovirus inflammation through IL-27 and B7-H4 (show VTCN1 Antibodies).

  3. IL-27 enhances the potential of reactive oxygen species generation from monocyte-derived macrophages and dendritic cells by induction of p47(phox).

  4. IL-27 has a unique ability to directly act on hematopoietic stem cells and promote their expansion and differentiation into myeloid progenitors in hematologic neoplasms and malaria. (Review)

  5. IL-27 rs153109 and rs17855750 Polymorphisms are associated with Risk and Response to Therapy in Acute Lymphoblastic Leukemia.

  6. IL-27 was down-regulated in the malignant Middle Cerebral Artery Infarction.

  7. IL-27 may be involved in the development of coronary artery lesions in acute Kawasaki disease.

  8. Hepatitis B virus infection can lead to overexpression of interleukin-27 gene in liver transplant patients.

  9. this study indicates that IL-27 secreted by cervical carcinoma cells restricts the angiogenesis in a paracrine manner in the pathogenesis of cervical cancer

  10. IL-27 signaling (IL-27 and its receptor) may be involved in the pathogenesis of HIV infection and immune reconstitution in HIV/AIDS patients who underwent HAART. IL-27 may exert effects through regulating Th1 (show TH1L Antibodies) / Th2 ratio.

Mouse (Murine) Interleukin 27 (IL27) interaction partners

  1. IL-27 has a unique ability to directly act on hematopoietic stem cells and promote their expansion and differentiation into myeloid progenitors in hematologic neoplasms and malaria. (Review)

  2. Mechanistic studies have identified that hyperlipidemia induces IL-27 production in a TLR4 (show TLR4 Antibodies)-dependent manner, likely via downregulating LXR (show NR1H3 Antibodies) expression in dendritic cells. In this case, mice lacking IL-27 do not develop enhanced antibody responses.

  3. IFN-gamma (show IFNG Antibodies) induces IL-30 production which suppresses IFN-gamma (show IFNG Antibodies) mediated liver inflammation.

  4. IL-27 signaling in Foxp3 (show FOXP3 Antibodies)(+) Tregs essential for Tregs to control autoimmune inflammation in the central nervous system

  5. this study indicates that IL-27 secreted by cervical carcinoma cells restricts the angiogenesis in a paracrine manner in the pathogenesis of cervical cancer

  6. this study has revealed an important role of thymic dendritic cells-derived IL-27 in the regulation of the phenotypic maturation of CD4 (show CD4 Antibodies)(+) single positive thymocytes.

  7. TTP (show ZFP36 Antibodies), encoded by Zfp36 (show ZFP36 Antibodies), degrades p28 (show GSTO1 Antibodies) to inhibit IL-27 production by macrophages and is thereby a negative regulator of the antitumour response.

  8. these data infer that endopeptidase mediated gliadin degradation by macrophages and concomitant IL-27 production drive differentiation of splenic gliadin-specific Tr1 (show TXNRD1 Antibodies)-like cells in celiac disease

  9. endogenous levels of IL-27 affected the oncogenic properties of mutant p53 (show TP53 Antibodies) in vivo in a Li-Fraumeni mouse model. Lack of IL-27 signaling led to shortened survival times and increased incidence of osteosarcomas.

  10. Interleukin-27 is upregulated centrally and peripherally after intracerebral hemorrhage. Interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least partly, the induction of lactoferrin (show LTF Antibodies).

Pig (Porcine) Interleukin 27 (IL27) interaction partners

  1. The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).

IL27 Antigen Profile

Protein Summary

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Gene names and symbols associated with anti-Interleukin 27 (IL27) Antibodies

  • interleukin 27 (IL27) antibody
  • interleukin 27 (Il27) antibody
  • IL-27 antibody
  • IL-27A antibody
  • IL-27p28 antibody
  • IL27 antibody
  • IL27A antibody
  • IL27p28 antibody
  • Il30 antibody
  • p28 antibody
  • RGD1561420 antibody

Protein level used designations for anti-Interleukin 27 (IL27) Antibodies

IL-27 p28 subunit , IL-27 subunit alpha , IL-27-A , IL27-A , interleukin 30 , interleukin-27 subunit alpha , interluekin 27 , interleukin 27 , interleukin 27 p28 subunit , p28

GENE ID SPECIES
246778 Homo sapiens
365368 Rattus norvegicus
607880 Canis lupus familiaris
614927 Bos taurus
737725 Pan troglodytes
246779 Mus musculus
493187 Sus scrofa
100349321 Oryctolagus cuniculus
100724612 Cavia porcellus
101122495 Ovis aries
101093822 Felis catus
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