Interleukin 28B (Interferon, lambda 3) (IL28B) ELISA Kits

IL28B encodes a cytokine distantly related to type I interferons and the IL-10 family. Additionally we are shipping Interleukin 28B (Interferon, lambda 3) Antibodies (111) and Interleukin 28B (Interferon, lambda 3) Proteins (18) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
IL28B 685840  
IL28B 338374 Q8CGK6
IL28B 282617 Q8IZI9
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Top Interleukin 28B (Interferon, lambda 3) ELISA Kits at

Showing 6 out of 32 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 3.1 pg/mL 7.8 pg/mL - 500 pg/mL 96 Tests Log in to see 13 to 16 Days
Mouse 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
  96 Tests Log in to see 26 to 36 Days
  96 Tests Log in to see 31 to 41 Days
Mouse 1 pg/mL 2.5 pg/mL - 600 pg/mL   96 Tests Log in to see 5 to 8 Days
Rat 0.938 ng/mL n/a   96 Tests Log in to see 16 to 21 Days

Top referenced Interleukin 28B (Interferon, lambda 3) ELISA Kits

  1. Human IL28B ELISA Kit for Sandwich ELISA - ABIN414558 : Rallón, Soriano, Naggie, Restrepo, McHutchison, Vispo, Benito: Impact of IL28B gene polymorphisms on interferon-?3 plasma levels during pegylated interferon-?/ribavirin therapy for chronic hepatitis C in patients coinfected with HIV. in The Journal of antimicrobial chemotherapy 2012 (PubMed)
    Show all 4 Pubmed References

  2. Human IL28B ELISA Kit for Sandwich ELISA - ABIN457021 : Khairy, Fouad, Mabrouk, El-Akel, Awad, Salama, Elnegouly, Shaker: The impact of interleukin 28b gene polymorphism on the virological response to combined pegylated interferon and ribavirin therapy in chronic HCV genotype 4 infected egyptian patients using data mining analysis. in Hepatitis monthly 2013 (PubMed)
    Show all 2 Pubmed References

More ELISA Kits for Interleukin 28B (Interferon, lambda 3) Interaction Partners

Mouse (Murine) Interleukin 28B (Interferon, lambda 3) (IL28B) interaction partners

  1. results suggest that IL-28B induces more mature NK cells to defend against viruses, in addition to its direct antiviral activity

  2. IL-28B down-regulates Tregs following subunit vaccine ESAT6-Ag85B-Mpt64(190-198)-Mtb8.4-HspX vaccination but does not improve the protective immune responses.

  3. the role of IFN-lambda in IDO regulation was investigated after influenza infection of respiratory epithelial cells.

  4. Data indicate that rotavirus infection induces production of interferon-lambda (IFN-lambda) and interleukin 22 (IL-22) by intestinal epithelial cells.

  5. Acritical role of IL-28 cytokines is in controlling T cell responses in vivo through the modulation of lung CD11c(+) DC function in experimental allergic asthma.

  6. IFN-lambda is involved in development and maintenance of oral tolerance in the intestines of mice.

  7. IFN-alpha, IFN-beta, and IFN-gamma were observed in the anterior segment of injected eyes through 72 hours and mRNA levels of IFN-beta and IFN-gamma were increased in virus-infected eyes 48 to 120 hours after herpes simplex infection

  8. the duration of IFNlambda signaling to JAK/STAT is different from that of IFNalpha

  9. intranasal influenza A virus infection leads to the robust type III IFN induction in the lungs of both WT and IFNAR-/- mice

  10. IFN-lambda contributes to the control of viral infections in epithelial cells of both respiratory and gastrointestinal tracts.

  11. IFN-lambda inhibits HBV replication and blocks replication of a subgenomic and a full-length genomic HCV replicon

  12. IL-28A emerges as a key regulatory cytokine with pathogenic function in T-cell-mediated liver injury

  13. Type III interferon/IL-28 targets a specific subset of cells and contributes to the antiviral response evoked by Toll-like receptors, largely mediated by inducing an antiviral state in epithelial cells.

  14. IFN-lambda contributes to inborn resistance against viral pathogens infecting the lung but not the liver

  15. IL-28B can induce 100% protection from mortality after a lethal influenza challenge

Human Interleukin 28B (Interferon, lambda 3) (IL28B) interaction partners

  1. No association between IFNL3 genotype and response to peginterferon alfa-2a in HBeAg-positive or -negative chronic hepatitis B patients was found.

  2. When analyzing the frequency of occurrence of a polymorphic variant T>G [rs8099917] IL-28B gene in children with chronic hepatitis C and healthy children revealed no differences in the distribution of alleles.

  3. zinc can act as a potent and specific inhibitor of IFN-lambda3 signaling.

  4. IL28B and MxA gene genotypes were detected among 231 chronic hepatitis C (CHC) carriers, 428 subjects with hepatitis C virus spontaneous clearance and 662 CHC patients with pegylated IFN-alpha and ribavirin (pegIFN-alpha/RBV) treatment.

  5. Single nucleotide polymorphisms (SNPs) rs12979860 and rs8099917 (IL28B) and rs1800896, rs1800871, and rs1800872 (IL10) are related to treatment outcome, but previous studies clustered nonresponse and relapse patients.Frequency of rs12979860 and rs8099917 is different between relapsers and nonresponders, but similar between relapsers and responders

  6. only IL28B rs12979860-CT and TT genotypes seem to contribute to the occurrence of chronic HCV infection in the cohort of Uruguayan population studied. Considering that a trend towards a higher frequency of "good" response genotypes was observed in responder patients, we believe that IL28B rs12979860 genotyping could be a useful tool for predicting different therapies outcome, including in the DAA era.

  7. our data show a significant association between rs12979860 polymorphism and hematologic response to IFN-alpha in PV and in the combined cohort of PV and ET. These findings imply that inborn variations in the genes involved in inflammation are related to the outcome of IFN-alpha treatment in MPNs.

  8. The selected donor with a predictable and favourable IL-28B genotype will not confer a benefit on the recipient in the living donor liver transplantation setting.

  9. IL-28B polymorphisms may be useful predictive factors for chronic periodontitis (CP) and correlated to the susceptibility to CP infection.

  10. IL28B rs12979860 polymorphism does not influence the susceptibility to HIV-1 and the AIDS development in Moroccan patients, however, this polymorphism may affect the response to HAART treatment as measured by CD4+ T cell counts

  11. This is the first report on a diagnostic test for simultaneous genotyping of IFNL3, ABCB11, and RNF7 in Chronic hepatitis C (CHC) patients. Reliable and inexpensive, the assay should provide useful information for the clinical management of CHC, like identification of patients at risk of rapid disease progression or with high chances of response to classic therapy.

  12. Results showed that INF-lambda serum concentration was increased in Alzheimer's disease (AD) and mild cognitive impairment (MCI) carrying the IFNL3 T allele compared to healthy controls (HC). Anti-HSV-1 Ab titers were higher in AD and MCI individuals carrying the IRF7 AA genotype compared to HC. IFNL3 rs12979860 and IRF7 rs6598008 polymorphisms may modulate immune responses against HSV-1 via their effect on the IFN-lam...

  13. Regardless of viral genotype we found no association between IL28B genotype and the risk of vertical transmission of HCV. The IL28B genotype CC, which has been shown to be favourable in other settings, was not protective of vertical transmission of HCV.

  14. The authors concluded that in the Chinese population, HLA-A*02:01 and DRB1*11:01 might be associated with the host capacity to clear hepatitis C virus independent of IL28B, which suggests that the innate and adaptive immune responses both play an important role in the control of hepatitis C virus.

  15. In a cohort of patients affected by HCV chronic hepatitis with genotypes 1 and 4, the prevalence of interleukin 28B (IL28B) genotypes, the possible association between IL28B polymorphism and severity of liver damage, the role of IL28B CC as a predictor of outcome were investigated

  16. Fine-tuned by RETN SNPs, intrahepatic, multi-cellular resistin reinforced IFNL3 in eliminating HCV via immunomodulation to counteract pro-inflammation.

  17. Investigated the associations of IL-28B rs12979860 and TBX21 rs17250932, rs4794067 polymorphisms with the susceptibility to, and outcomes of, hepatitis C virus (HCV) infection; results showed no significant associations for rs12979860 polymorphisms with HCV clearance and sustained virological response

  18. IFNL3 rs4803217 SNP is a strong, independent and superior predictor of sustained virological response and relapse in HCV genotype 1 infected chronic hepatitis C patients treated with pegylated interferon alpha and ribavirin.

  19. IL-28B single nucleotide polymorphism rs8099917TT is the most frequent genotype in Cuban chronic hepatitis C patients and is associated with treatment outcome as well.

  20. Liver stiffness progression in patients with chronic hepatitis C virus correlated with the IL28B TT/CC and IL28B GG/TT genotypes.

Interleukin 28B (Interferon, lambda 3) (IL28B) Antigen Profile

Antigen Summary

This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).

Gene names and symbols associated with IL28B

  • interferon, lambda 3 (Ifnl3) antibody
  • interferon lambda 3 (IFNL3) antibody
  • interferon lambda 3 (Ifnl3) antibody
  • IFL-1 antibody
  • IL-28B antibody
  • Il28 antibody
  • IL28B antibody
  • IL28C antibody
  • INF-alpha antibody
  • INF-lambda antibody

Protein level used designations for IL28B

interleukin 28B , interleukin-29 , IFN-lambda-3 , interferon alpha , interferon lambda-3 , interleukin 28 , interleukin-28B , IFN-lambda-4 , IL-28C , cytokine Zcyto22 , interferon lambda-4 , interferon, lambda 4 , interleukin 28B (interferon, lambda 3) , interleukin 28C , interleukin-28C

685840 Rattus norvegicus
100620067 Bos taurus
338374 Mus musculus
282617 Homo sapiens
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