Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
IL28B encodes a cytokine distantly related to type I interferons and the IL-10 family. Additionally we are shipping Interleukin 28B (Interferon, lambda 3) Antibodies (113) and Interleukin 28B (Interferon, lambda 3) Proteins (14) and many more products for this protein.
Showing 6 out of 28 products:
Human IL28B ELISA Kit for Sandwich ELISA - ABIN414558
Rallón, Soriano, Naggie, Restrepo, McHutchison, Vispo, Benito: Impact of IL28B gene polymorphisms on interferon-?3 plasma levels during pegylated interferon-?/ribavirin therapy for chronic hepatitis C in patients coinfected with HIV. in The Journal of antimicrobial chemotherapy 2012
Show all 4 Pubmed References
Human IL28B ELISA Kit for Sandwich ELISA - ABIN457021
Khairy, Fouad, Mabrouk, El-Akel, Awad, Salama, Elnegouly, Shaker: The impact of interleukin 28b gene polymorphism on the virological response to combined pegylated interferon and ribavirin therapy in chronic HCV genotype 4 infected egyptian patients using data mining analysis. in Hepatitis monthly 2013
Show all 2 Pubmed References
results suggest that IL-28B induces more mature NK cells to defend against viruses, in addition to its direct antiviral activity
IL-28B down-regulates Tregs following subunit vaccine ESAT6-Ag85B-Mpt64(190-198)-Mtb8.4-HspX (show HSP ELISA Kits) vaccination but does not improve the protective immune responses.
the role of IFN-lambda in IDO (show IDO1 ELISA Kits) regulation was investigated after influenza infection of respiratory epithelial cells.
Data indicate that rotavirus infection induces production of interferon (show IFNA ELISA Kits)-lambda (IFN-lambda) and interleukin 22 (IL-22 (show IL22 ELISA Kits)) by intestinal epithelial cells.
Acritical role of IL-28 cytokines is in controlling T cell responses in vivo through the modulation of lung CD11c (show ITGAX ELISA Kits)(+) DC function in experimental allergic asthma.
IFN-alpha (show IFNA ELISA Kits), IFN-beta (show IFNB1 ELISA Kits), and IFN-gamma (show IFNG ELISA Kits) were observed in the anterior segment of injected eyes through 72 hours and mRNA levels of IFN-beta (show IFNB1 ELISA Kits) and IFN-gamma (show IFNG ELISA Kits) were increased in virus-infected eyes 48 to 120 hours after herpes simplex infection
the duration of IFNlambda signaling to JAK (show JAK3 ELISA Kits)/STAT (show STAT1 ELISA Kits) is different from that of IFNalpha
intranasal influenza A virus infection leads to the robust type III IFN induction in the lungs of both WT and IFNAR (show IFNAR1 ELISA Kits)-/- mice
IL-28A (show IL28A ELISA Kits) emerges as a key regulatory cytokine with pathogenic function in T-cell-mediated liver injury
Type III interferon (show IFNA ELISA Kits)/IL-28 targets a specific subset of cells and contributes to the antiviral response evoked by Toll (show TLR4 ELISA Kits)-like receptors, largely mediated by inducing an antiviral state in epithelial cells.
The authors concluded that in the Chinese population, HLA-A*02:01 and DRB1 (show RBM45 ELISA Kits)*11:01 might be associated with the host capacity to clear hepatitis C virus independent of IL28B, which suggests that the innate and adaptive immune responses both play an important role in the control of hepatitis C virus.
In a cohort of patients affected by HCV chronic hepatitis with genotypes 1 and 4, the prevalence of interleukin 28B (IL28B) genotypes, the possible association between IL28B polymorphism and severity of liver damage, the role of IL28B CC as a predictor of outcome were investigated
Fine-tuned by RETN (show RETN ELISA Kits) SNPs, intrahepatic, multi-cellular resistin (show RETN ELISA Kits) reinforced IFNL3 in eliminating HCV via immunomodulation to counteract pro-inflammation.
Investigated the associations of IL-28B rs12979860 and TBX21 rs17250932, rs4794067 polymorphisms with the susceptibility to, and outcomes of, hepatitis C virus (HCV) infection; results showed no significant associations for rs12979860 polymorphisms with HCV clearance and sustained virological response
IFNL3 rs4803217 SNP is a strong, independent and superior predictor of sustained virological response and relapse in HCV genotype 1 infected chronic hepatitis C patients treated with pegylated interferon alpha (show IFNA ELISA Kits) and ribavirin.
IL-28B single nucleotide polymorphism rs8099917TT is the most frequent genotype in Cuban chronic hepatitis C patients and is associated with treatment outcome as well.
Liver stiffness progression in patients with chronic hepatitis C virus correlated with the IL28B TT/CC and IL28B GG/TT genotypes.
IL28B (rs8099917 and rs12979860) and IL10 (show IL10 ELISA Kits) (rs1800896) polymorphisms alone, or in combination, are good predictors of therapeutic response in hepatitis C virus-3a patients.
In this study, limit of detection (LD), costs and turnaround time of these methods were compared in 350 subjects. As for IL28B rs12979860 polymorphisms, 348/350 (99.4%) samples were consistent among the five methods, while results for 2/350 (0.57%) samples were concordant by ZNAs and PCR-sequencing, and discordant by other methods
Of the 1084 patients with the IL-28 genotype, 59.4% had hepatitis C virus genotype 1 (HCV-1) infection; 85.6% had the TT genotype. Patients with advanced liver fibrosis had an older age, a lower platelet count, a higher [alpha]-fetoprotein level, a higher alanine aminotransferase (show ALT ELISA Kits) level, a higher incidence of diabetes, and a higher frequency of rs8099917 non-TT genotype carriage.
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
, interferon alpha
, interferon lambda-3
, interleukin 28
, cytokine Zcyto22
, interferon lambda-4
, interferon, lambda 4
, interleukin 28B (interferon, lambda 3)
, interleukin 28C